Results 91 to 100 of about 22,605,370 (372)

Developmental and pathological lymphangiogenesis: from models to human disease [PDF]

, 2018
The lymphatic vascular system, the body's second vascular system present in vertebrates, has emerged in recent years as a crucial player in normal and pathological processes.
Maby-El Hajjami, Hélène, Petrova, Tatiana   +1 more
core  

The Lymphatic System in Obesity, Insulin Resistance, and Cardiovascular Diseases

Frontiers in Physiology, 2019
Obesity, insulin resistance, dyslipidemia, and hypertension are fundamental clinical manifestations of the metabolic syndrome. Studies over the last few decades have implicated chronic inflammation and microvascular remodeling in the development of ...
Xinguo Jiang, W. Tian, M. Nicolls, S. Rockson   +3 more
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Lymphatic endothelial sphingosine 1-phosphate receptor 1 enhances macrophage clearance via lymphatic system following myocardial infarction

Frontiers in Cardiovascular Medicine, 2022
Lymphatic endothelial cell homeostasis plays important roles in normal physiological cardiac functions, and its dysfunction significantly influences pathological cardiac remodeling after myocardial infarction (MI). Our results revealed that sphingosine 1-
Qinyu Li, Caixia Zhou, Kang Zhao, Yunhao Duan, Jinnan Yue, Xiuxiang Liu, Jinjin Wu, Shengqiong Deng   +7 more
doaj   +1 more source

Spatio-temporal Models of Lymphangiogenesis in Wound Healing

, 2016
Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries.
A Bianchi, A Castiglioni, A Christiansen, A Friedman, A Gosiewska, A Louveau, A Mantovani, A Saaristo, A Stéphanou, AB Sutton, AI Papaioannou, AJ Macdonald, AJ Singer, Arianna Bianchi, AV Benest, AW Taylor, AY Sheikh, B Greenwood, B Kaminska, B Whitehurst, BE Farrell, BM Berg van den, C Cao, C Heppell, C Norrmen, CA Cobbold, CH Cho, CL Helm, CT Ambrose, D Ludwig, DJ Grainger, DR Brown, E Hormbrey, E Mendoza, EK Rofstad, ETT Withington, F Krombach, F Mac Gabhann, G Crescenzo De, G Müller, G Oliver, GF Pierce, GJ Goodhill, H Brem, H Kaur, H Staden von, HA Levine, HM Byrne, HM Byrne, HV Waugh, I Barkefors, I Choi, I Nunes, I Zachary, J Asai, J Goldman, J Posnett, JA Flegg, JC Zhuang, JD Shields, JF Douglas, JJL Velázquez, JJL Velázquez, JM Rutkowski, JM Rutkowski, Jonathan A. Sherratt, JP Yang, K Maruyama, K Weber-Matthiesen, KC Boardman, KE Murphy, Kevin J. Painter, KN Margaris, L Edelstein, L Yang, LM Wakefield, M Fischer, M Hyytiäinen, M Lohela, M Oi, M Scianna, M Shi, MAJ Chaplain, ME Fleury, ME Swift, MH Witte, MTGT May, N Khalil, N Khalil, N Li Jeon, NP Reddy, NV Mantzaris, P Drew, P Galie, PN Bernatchez, R Boulton, R Huggenberger, RC Ji, RC Schugart, RH Adams, RS Sweat, RT Tranquillo, S Kiriakidis, S Lee, S Monstrey, S Podgrabinska, S Zimny, SJ Lunt, SM Wahl, T Miura, T Roose, T Tammela, TG Simonsen, TL Haas, VPKH Nguyen, WJ Jeffcoate, Y Cao, Y Zheng   +117 more
core   +1 more source

Lymphangiography to treat postoperative lymphatic leakage: a technical review. [PDF]

, 2014
In addition to imaging the lymphatics and detecting various types of lymphatic leakage, lymphangiography is a therapeutic option for patients with chylothorax, chylous ascites, and lymphatic fistula.
Kim, Soo Hwan, Ko, Heung Kyu, Lee, Edward Wolfgang, Park, Jihong, Shin, Ji Hoon, Sung, Kyu-Bo   +5 more
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

The interstitial compartment as a therapeutic target in heart failure

Frontiers in Cardiovascular Medicine, 2022
Congestion is the single most important contributor to heart failure (HF) decompensation. Most of the excess volume in patients with HF resides in the interstitial compartment.
Doron Aronson
doaj   +1 more source

Role of Lymphatic Vessels in Tumor Immunity: Passive Conduits or Active Participants? [PDF]

, 2018
Research in lymphatic biology and cancer immunology may soon intersect as emerging evidence implicates the lymphatics in the progression of chronic inflammation and autoimmunity as well as in tumor metastasis and immune escape. Like the blood vasculature,
Lund, Amanda, Swartz, Melody
core  

The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination [PDF]

, 2012
Background: Neglected tropical diseases (NTDs) are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2·7 billion people globally living on less than US$2 per day.
A Alemu, A Aseffa, A Deressa, A Haileamlak, A Yami, Abraham Aseffa, AD Bryceson, Ahmed Ali, AM Dorkenoo, Asrat Hailu, AZ Zein, B Erko, B Erko, B Liese, B Yakob, BA Boatin, C Bogh, C Hanson, C Prasittisuk, C Sikorski, Central Statistical Agency [Ethiopia], ICF International, D Fekadu, DG Addiss, DH Molyneux, DH Molyneux, DR ten Eyck, E Litt, E Negera, E Negera, E Ruiz-Tiben, E Yimer, EW Price, F Demissie, F Tekola, FMOH, FMOH, FMoH, G Davey, G Davey, G Davey, G Mengistu, G Tefera, Gail Davey, GS Smith, H Birrie, H Kloos, H Kloos, J Alvar, J Alvar, JH Kolaczinski, JH Kolaczinski, JO Gyapong, K Bogel, KA Grépin, Kadu Meribo, Kebede Deribe, L Erosie, L Jemaneh, M Fekadu, M Fekadu, M Herrero, MA Brady, MC Baker, Ministry of Health, MJ Burton, MJ Taylor, N Kebede, NB Kabatereine, P Steinmann, PJ Hotez, PJ Hotez, PJ Hotez, PJ Hotez, PJ Hotez, PM Emerson, R ter Horst, RL Pullan, RW Ashford, S Bashaye, S Brooker, S Brooker, S Cairncross, S Negash, SG Gundersen, T Wondimagegnehu, Teshome Gebre, The Carter Center, W Shiferaw, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, Y Berhane, Z Tadesse, ZA Zein   +103 more
core   +2 more sources