Results 101 to 110 of about 18,325,039 (298)
Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
Advanced Materials, EarlyView.As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source
Seventh meeting of the Global Alliance to Eliminate Lymphatic Filariasis: reaching the vision by scaling up, scaling down, and reaching out [PDF]
, 2014 This report summarizes the 7th meeting of the Global Alliance to Eliminate Lymphatic Filariasis (GAELF), Washington DC, November 18–19, 2012. The theme, “A Future Free of Lymphatic Filariasis: Reaching the Vision by Scaling Up, Scaling Down and Reaching ...
Global Alliance, Eliminate Lymphatic Filariasis +4 more
core +1 more source
Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy
Advanced Materials, EarlyView.MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo +9 more
wiley +1 more source
, 2019 Albeit often neglected, the lymphatic system serves multiple functions to the cardiovascular system, the most relevant being volume homeostasis. In this chapter we describe the anatomy and physiology of lymphatic vessels: while sharing many aspects with ...
Rockson, Stanley G. +5 more
core +1 more source
Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic
Advanced Robotics Research, EarlyView.Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang +5 more
wiley +1 more source
Lymph Drainage of the Mammary Glands in Female Cats [PDF]
, 2006 The mammary gland is a common site of neoplasms in the female cat. All the malignant tumors metastasize to a lesser or a greater extent through the lymphatic system.
Sautet, Jean, Raharison, Fidiniaina
core +1 more source
Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges
Advanced Robotics Research, EarlyView.Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
Advanced Science, EarlyView.A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
NPG Asia MaterialsThe human cutaneous lymphatic system strictly controls lymphatic functions by coordinating with skin cells. The lymphatic system plays important roles in removing cell waste, residual proteins, various antigens, and immune cells from tissues to maintain ...
Minseop Kim +12 more
doaj +1 more source