Results 121 to 130 of about 273,500 (290)

Investigating the Role of the Central Lymphatic System in the Pathogenesis of Neurodegenerative Diseases

Guoji laonian yixue zazhi
The central lymphatic system comprises the glymphatic system, which is present throughout the brain, and the cerebrospinal fluid drainage route, which includes meningeal lymphatic vessels, cranial nerves, and cervical lymphatic channels. The primary role
Xian Zhang, Peng Liu, Libo Zou
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

The emerging role of biomaterial applications in cerebral lymphatic surgical interventions: A narrative review

Biomaterials and Biosystems
The cerebral lymphatic system plays a critical role in central nervous system (CNS) homeostasis through fluid regulation, toxin clearance, and immune modulation.
Mark Jessup, Nicholas J. Iglesias, Kashyap K. Tadisina, Kyle Xu, Juan Mella-Catinchi, Leonard Pinchuk, Devinder Singh, David T. Tse, Vasudev Vivekanand Nayak, Paulo G. Coelho   +9 more
doaj   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Meningeal Lymphatic and Glymphatic Structures in a Pelagic Delphinid (Delphinus delphis)

Animals
The glymphatic system, an analog of the peripheral lymphatic system in the brain, and the meningeal lymphatic system are critical to central nervous system health.
Olivia N. Jackson, Tiffany F. Keenan, Nathan P. Nelson-Maney, Sentiel A. Rommel, William A. McLellan, D. Ann Pabst, Alexander M. Costidis, Kathleen M. Caron, Dawn N. Kernagis, David S. Rotstein, Victoria G. Thayer, Craig A. Harms, Marina A. Piscitelli-Doshkov, Paul Doshkov, Lorian E. Schweikert, Kara E. Yopak, Molly Braun, Michael S. Tift   +17 more
doaj   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Lower Extremity Lymphatic Flow/Drainage Assessment by Indocyanine Green Fluorescent Lymphography in Heart Failure Patients

JACC: Basic to Translational Science
Summary: The purpose of this study was to present a protocol for visualizing lymphatic flow in patients with heart failure (HF) by using indocyanine green fluorescence lymphography.
Barbara Ponikowska, MD, Jan Biegus, MD, PhD, Marat Fudim, MD, MHS, Gracjan Iwanek, MD, Mateusz Guzik, MD, Roman Przybylski, MD, PhD, Andrzej Szuba, MD, PhD, Angelika Chachaj, MD, PhD, Robert Zymliński, MD, PhD   +8 more
doaj   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Analysis of norepinephrine-regulated cerebral lymphatic drainage by the second near-infrared region in vivo imaging

APL Photonics
The cerebral lymphatic drainage plays an important role in the occurrence and development of central nervous system diseases. Recent studies have shown that cerebral lymphatic drainage is regulated by circadian rhythm and anesthesia state; however, the ...
Xi Li, Tianhao Yang, Zhongyang Zhang, Shengnan Wu, Zhen Yuan, Feifan Zhou   +5 more
doaj   +1 more source

Therapeutic approaches to CNS diseases via the meningeal lymphatic and glymphatic system: prospects and challenges

Frontiers in Cell and Developmental Biology
The brain has traditionally been considered an “immune-privileged” organ lacking a lymphatic system. However, recent studies have challenged this view by identifying the presence of the glymphatic system and meningeal lymphatic vessels (MLVs).
Rui Zhang, Jiuhong Li, Xueying Li, Si Zhang   +3 more
doaj   +1 more source