Results 121 to 130 of about 22,436,913 (372)

Neurotrophic keratitis in a patient with disseminated lymphangiomatosis. [PDF]

, 2009
INTRODUCTION: Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat.
Charukamnoetkanok, Puwat, Knickelbein, Jared E, Stefko, Susan T   +2 more
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

FUNCTIONS OF THE LYMPHATIC SYSTEM. [PDF]

The Lancet
n ...
openaire   +2 more sources

Hematologic and lymphatic disorders associated with chimeric antigen receptor T-cell therapy: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database

BMC Cancer
Background As the application of Chimeric Antigen Receptor T-cell (CAR-T) therapy in cancer treatment becomes increasingly widespread, associated hematologic and lymphatic system adverse events pose significant challenges to its clinical use.
Zhenpo Zhang, Jingping Zheng, Yankun Liang, Qimin Wu, Chufeng Ding, Lin Ma, Ling Su   +6 more
doaj   +1 more source

Constitution of the Lymphatic System [PDF]

, 2012
The lymphatic system consists of two types segments – general (systemic or periarterial) and special (own, intervalvular). The segments organize all the system’s reactions in response to its environmental influences.
Valeriy M. Petrenko, PhD, ScD
core  

Dosing pole recommendations for lymphatic filariasis elimination: A height-weight quantile regression modeling approach [PDF]

, 2019
BACKGROUND: The World Health Organization (WHO) currently recommends height or age-based dosing as alternatives to weight-based dosing for mass drug administration lymphatic filariasis (LF) elimination programs.
Dubray, Christine, Fischer, Peter U, Goss, Charles W, Hardy, Myra, Jambulingam, Purushothaman, King, Christopher L, Laman, Moses, Lemoine, Jean Frantz, O\u27Brian, Katiuscia, Robinson, Leanne J, Samuela, Josaia, Schechtman, Kenneth B, Subramanian, Swaminathan, Supali, Taniawati, Weil, Gary J   +14 more
core   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Assessing the presence of Wuchereria bancrofti in vector and human populations from urban communities in Conakry, Guinea [PDF]

, 2015
The Global Programme to Eliminate Lymphatic Filariasis was launched in 2000 with the goal of interrupting transmission of lymphatic filariasis (LF) through multiple rounds of mass drug administration (MDA).
Boakye, Daniel A., Bockarie, Moses J., Dadzie, Samuel K., de Souza, Dziedzom K., Diakité, Lamia, Goepogui, Andre, King, Sandra A., Kouassi, Bernard L., Koudou, Benjamin G., Mamadou, Baldé S., Narh, Charles A., Utzinger, Jürg   +11 more
core   +3 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li, Grace M. Aldrovandi, Hye Ryun Yu, Hye-Ra Lee, Jae U. Jung, Peter Palese, Pinghui Feng, Shou-Jiang Gao, Un Yung Choi, Young-Kwon Hong   +9 more
core   +3 more sources