Results 221 to 230 of about 276,175 (315)

Lymphatic system in the brain. [PDF]

Ann Med Surg (Lond), 2022
Khan S, Abdulla E, Rahman MM.
europepmc   +1 more source

First-in-human Use of a Microsurgical Robotic System for Central Lymphatic Reconstruction

, 2023
Lisanne Grünherz, Andrea Weinzierl, Gilbert Puippe, Donata von Reibnitz, Carlotta Barbon, Marcel Schneider, Pietro Giovanoli, Christian A. Gutschow, Nicole Lindenblatt   +8 more
openalex   +1 more source

Foundation Model‐Enabled Multimodal Deep Learning for Prognostic Prediction in Colorectal Cancer with Incomplete Modalities: A Multi‐Institutional Retrospective Study

Advanced Science, EarlyView.
FLARE, a multimodal AI framework, combines pathology slides, radiology scans, and clinical reports to predict colorectal cancer outcomes, even when some tests are missing. Evaluated retrospectively in 1679 patients from four medical centers, it consistently achieved the best prognostic accuracy and clearly separated high‐ and low‐risk groups.
Linhao Qu, Chengsheng Zhang, Yingyong Hou, Feng Tang, Weiqi Sheng, Dan Huang, Zhijian Song   +6 more
wiley   +1 more source

To explore the targeting of toluidine blue: low molecular dextran-40 to the lymphatic system and its effect assessment. [PDF]

Sci Rep
Liu F, Sui Y, Yang M, Wan S, Li W, Shang W, Cui J.   +6 more
europepmc   +1 more source

Progress on Brain and Ocular Lymphatic System. [PDF]

Biomed Res Int, 2022
Xu Y, Cheng L, Yuan L, Yi Q, Xiao L, Chen H.   +5 more
europepmc   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Integrated gross and microanatomical analysis of the periportal lymphatic system in human liver. [PDF]

J Hepatobiliary Pancreat Sci
Mitsuhashi Y, Shimoda H, Umemura K, Kagiya T, Sato K, Narita H, Chiba T, Ishido K, Kimura N, Hakamada K.   +9 more
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

Functional and Clinical Relevance of the Crosstalk between the Glymphatic System and the Lymphatic System. [PDF]

Curr Neuropharmacol
Khabibov M, Garifullin A, Sadreeva A, Fernandez MF, Kashaev M, Topchu I, Kharin L, Boumber Y.   +7 more
europepmc   +1 more source