Results 21 to 30 of about 1,057,574 (234)

Fluorescent Tracers for In Vivo Imaging of Lymphatic Targets

Frontiers in Pharmacology, 2022
The lymphatic system continues to gain importance in a range of conditions, and therefore, imaging of lymphatic vessels is becoming more widespread for research, diagnosis, and treatment. Fluorescent lymphatic imaging offers advantages over other methods
P. S. Russell, P. S. Russell, R. Velivolu, R. Velivolu, V. E. Maldonado Zimbrón, V. E. Maldonado Zimbrón, J. Hong, J. Hong, J. Hong, I. Kavianinia, I. Kavianinia, A. J. R. Hickey, A. J. R. Hickey, J. A. Windsor, J. A. Windsor, A. R. J. Phillips, A. R. J. Phillips, A. R. J. Phillips   +17 more
doaj   +1 more source

Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]

, 2014
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise, Chuva de Sousa Lopes, Susana Marina, de Koning, Eelco JP, de Melo Bernardo, Ana, Mummery, Christine L, Roost, Matthias S, van Iperen, Liesbeth   +6 more
core   +1 more source

Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment

Cell Death and Differentiation, 2020
Clinical response to immunotherapy is closely associated with the immunosuppressive tumour microenvironment (TME), and influenced by the dynamic interaction between tumour cells and lymphatic endothelial cells (LECs).
Chenfei Zhou, Yanmei Zhang, Ruiming Yan, Lei Huang, A. Mellor, Yang Yang, Xiaojing Chen, Wenfei Wei, Xiangguang Wu, Lan Yu, Luojiao Liang, Dan Zhang, Sha Wu, Wei Wang   +13 more
semanticscholar   +1 more source

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker, Gelinsky, Michael, Hanke, Thomas, Hartmann, Sonja, Heinemann, Sascha, Heiss, Christian, Kampschulte, Marian, Kauschke, Vivien, Kautz, Armin R., Kilian, Olaf, Langheinrich, Alexander, Lips, Katrin Susanne, Ray, Seemun, Schnabelrauch, Matthias, Schnettler, Reinhard, Schumacher, Matthias, Thormann, Ulrich   +16 more
core   +2 more sources

Subdural haematomas drain into the extracranial lymphatic system through the meningeal lymphatic vessels

Acta Neuropathologica Communications, 2020
Subdural haematomas (SDHs) are characterized by rapidly or gradually accumulated haematomas between the arachnoid and dura mater. The mechanism of haematoma clearance has not been clearly elucidated until now.
Xuanhui Liu, Chuang Gao, Jiangyuan Yuan, Tangtang Xiang, Zhitao Gong, Hongliang Luo, Weiwei Jiang, Yiming Song, Jinhao Huang, W. Quan, Dong Wang, Ye Tian, X. Ge, P. Lei, Jian-ning Zhang, Rongcai Jiang   +15 more
semanticscholar   +1 more source

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling

bioRxiv, 2020
During the growth of lymphatic vessels (lymphangiogenesis), lymphatic endothelial cells (LECs) at the growing front sprout by forming filopodia. Those tip cells are not exposed to circulating lymph, as they are not lumenized. In contrast, LECs that trail
Xin Geng, K. Yanagida, R. Akwii, Dongwon Choi, Li-Jun Chen, Y. Ho, B. Cha, Md Riaj Mahamud, Karen Berman de Ruiz, H. Ichise, Hong Chen, Joshua D. Wythe, Constantinos M Mikelis, T. Hla, R. Srinivasan   +14 more
semanticscholar   +1 more source

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Frontiers in Cell and Developmental Biology, 2023
Complex lymphatic anomalies (CLAs) are sporadically occurring diseases caused by the maldevelopment of lymphatic vessels. We and others recently reported that somatic activating mutations in KRAS can cause CLAs.
Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger, Michael T. Dellinger   +7 more
doaj   +1 more source

High relative density of lymphatic vessels predicts poor survival in tongue squamous cell carcinoma [PDF]

, 2016
Tongue cancer has a poor prognosis due to its early metastasis via lymphatic vessels. The present study aimed at evaluating lymphatic vessel density, relative density of lymphatic vessel, and diameter of lymphatic vessels and its predictive role in ...
Huhtala, Heini, Laranne, Jussi, Lemstrom, Karl, Paavonen, Timo, Pohjola, Konsta, Rautiainen, Markus, Renkonen, Risto, Seppälä, Miia, Toppila-Salmi, Sanna   +8 more
core   +1 more source

Lymphatic Vessels and Their Surroundings: How Local Physical Factors Affect Lymph Flow

Biology, 2020
Simple Summary Lymphatic vessels are responsible for the drainage of liquids, solutes, and cells from interstitial spaces and serosal cavities. Their task is fundamental in order to avoid fluid accumulation leading to tissue swelling and edema.
E. Solari, C. Marcozzi, D. Negrini, A. Moriondo   +3 more
semanticscholar   +1 more source

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis. [PDF]

, 2013
Lymphatic vessels transport fluid, antigens, and immune cells to the lymph nodes to orchestrate adaptive immunity and maintain peripheral tolerance. Lymphangiogenesis has been associated with inflammation, cancer metastasis, autoimmunity, tolerance and ...
Golab, J., Kilarski, W.W., Muchowicz, A., Mężyk-Kopeć, R., Nowak-Sliwinska, P., Swartz, M.A., Wachowska, M.   +6 more
core   +1 more source