Results 21 to 30 of about 104,618 (343)

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. [PDF]

, 2017
T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Coles, Marc, Debes, Gudrun F., Detmar, Michael, Frei, Thomas, Halin, Cornelia, Hunter, Morgan C., Melero, Ignacio, Proulx, Steven T, Rouzaut, Ana, Russo, Erica, Teijeira, Alvaro   +10 more
core   +3 more sources

Focus on the Lymphatic Route to Optimize Drug Delivery in Cardiovascular Medicine

Pharmaceutics, 2021
While oral agents have been the gold standard for cardiovascular disease therapy, the new generation of treatments is switching to other administration options that offer reduced dosing frequency and more efficacy.
Nolwenn Tessier, Fatma Moawad, Nada Amri, Davide Brambilla, Catherine Martel   +4 more
doaj   +1 more source

Magnetic resonance imaging of cerebrospinal fluid outflow after low-rate lateral ventricle infusion in mice

JCI Insight, 2022
The anatomical routes for the clearance of cerebrospinal fluid (CSF) remain incompletely understood. However, recent evidence has given strong support for routes leading to lymphatic vessels. A current debate centers upon the routes through which CSF can
Yann Decker, Jonas Krämer, Li Xin, Andreas Müller, Anja Scheller, Klaus Fassbender, Steven T. Proulx   +6 more
doaj   +1 more source

Three-dimensional imaging of vascular development in the mouse epididymis

eLife, 2023
Long considered an accessory tubule of the male reproductive system, the epididymis is proving to be a key determinant of male fertility. In addition to its secretory role in ensuring functional maturation and survival of spermatozoa, the epididymis has ...
Christelle Damon-Soubeyrand, Antonino Bongiovanni, Areski Chorfa, Chantal Goubely, Nelly Pirot, Luc Pardanaud, Laurence Piboin-Fragner, Caroline Vachias, Stephanie Bravard, Rachel Guiton, Jean-Leon Thomas, Fabrice Saez, Ayhan Kocer, Meryem Tardivel, Joël R Drevet, Joelle Henry-Berger   +15 more
doaj   +1 more source

Differential regulation of lymphatic junctional morphology and the potential effects on cardiovascular diseases

Frontiers in Physiology, 2023
The lymphatic vasculature provides an essential route to drain fluid, macromolecules, and immune cells from the interstitium as lymph, returning it to the bloodstream where the thoracic duct meets the subclavian vein.
Amanda M. Peluzzo, Meriem Bkhache, Long Nguyen Hoang Do, Michael V. Autieri, Xiaolei Liu   +4 more
doaj   +1 more source

Heartbreak hotel: a convergence in cardiac regeneration [PDF]

, 2016
In February 2016, the Company of Biologists hosted an intimate gathering of leading international researchers at the forefront of experimental cardiovascular regeneration, with its emphasis on ‘Transdifferentiation and Tissue Plasticity in Cardiovascular
Schneider, MD
core   +1 more source

A new paradigm in intracellular immunology: Mitochondria emerging as leading immune organelles

Redox Biology
Mitochondria, traditionally recognized as cellular 'powerhouses' due to their pivotal role in energy production, have emerged as multifunctional organelles at the intersection of bioenergetics, metabolic signaling, and immunity.
Keman Xu, Fatma Saaoud, Ying Shao, Yifan Lu, Qiaoxi Yang, Xiaohua Jiang, Hong Wang, Xiaofeng Yang   +7 more
doaj   +1 more source

Co-localization of lymphoid aggregates and lymphatic networks in nose- (NALT) and lacrimal duct-associated lymphoid tissue (LDALT) of mice

BMC Immunology, 2018
Background The lymphatic vascular pattern in the head of mice has rarely been studied, due to problems of sectioning and immunostaining of complex bony structures.
Melanie Lohrberg, Reinhard Pabst, Jörg Wilting   +2 more
doaj   +1 more source

Adventitial lymphatics of internal carotid artery in healthy and atherosclerotic vessels.

Folia Histochemica et Cytobiologica, 2009
<strong>OBJECTIVES</strong><br />Presence of lymphatics in adventitia of major arteries remains controversial. Presence of lymphatics in adventitia of internal carotid artery was not documented and its relation to atherosclerosis was ...
Ryszard Andrzejak, Piotr Ziółkowski, Dariusz Patrzałek, Marzena Podhorska, Piotr Dziegiel, Dariusz Janczak, Katarzyna Drozdz, Andrzej Szuba   +7 more
doaj   +1 more source

The lymphatic system in alcohol-associated liver disease [PDF]

Clinical and Molecular Hepatology, 2020
The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood.
Reiichiro Kondo, Yasuko Iwakiri
doaj   +1 more source