Results 41 to 50 of about 171,634 (197)

Adventitial lymphatics of internal carotid artery in healthy and atherosclerotic vessels.

Folia Histochemica et Cytobiologica, 2009
<strong>OBJECTIVES</strong><br />Presence of lymphatics in adventitia of major arteries remains controversial. Presence of lymphatics in adventitia of internal carotid artery was not documented and its relation to atherosclerosis was ...
Ryszard Andrzejak, Piotr Ziółkowski, Dariusz Patrzałek, Marzena Podhorska, Piotr Dziegiel, Dariusz Janczak, Katarzyna Drozdz, Andrzej Szuba   +7 more
doaj   +1 more source

Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain

eLife, 2022
The discovery of meningeal lymphatic vessels that drain the CNS has prompted new insights into how immune responses develop in the brain. In this study, we examined how T cell responses against CNS-derived antigen develop in the context of infection.
Michael A Kovacs, Maureen N Cowan, Isaac W Babcock, Lydia A Sibley, Katherine Still, Samantha J Batista, Sydney A Labuzan, Ish Sethi, Tajie H Harris   +8 more
doaj   +1 more source

A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo [PDF]

, 2012
In vivo imaging has revolutionized understanding of the spatiotemporal complexity that subserves the generation of successful effector and regulatory immune responses.
Andrea J. White, Butcher, Cardillo, Carragher, Catherine M. Rush, Celli, de Boer, Eric J. Jenkinson, Farr, Fulmer, Gianluca Grassia, Girard, Graham Anderson, Gunn, Hillebrands, Huang, Iain B. McInnes, Itano, James M. Brewer, Karen J. Bryson, Kono, Lane, Leishman, Luther, McNagny, Millington, Pasquale Maffia, Paul Garside, Proudman, Robert A. Benson, Schneider, Smith, Stutzmann, Sumen, Tammela, Tomei, Vivienne B. Gibson, White, Worbs, Yoshida, Zinselmeyer   +40 more
core   +2 more sources

Dermal Lymphatic Capillaries Do Not Obey Murray's Law

Frontiers in Cardiovascular Medicine, 2022
Lymphatic vessels serve as a major conduit for the transport of interstitial fluid, immune cells, lipids and drugs. Therefore, increased knowledge about their development and function is relevant to clinical issues ranging from chronic inflammation and ...
Anne M. Talkington, Anne M. Talkington, Reema B. Davis, Nicholas C. Datto, Emma R. Goodwin, Laura A. Miller, Kathleen M. Caron   +6 more
doaj   +1 more source

Perspective: Pathological transdifferentiation—a novel therapeutic target for cardiovascular diseases and chronic inflammation

Frontiers in Cardiovascular Medicine
Pathological transdifferentiation, where differentiated cells aberrantly transform into other cell types that exacerbate disease rather than promote healing, represents a novel and significant concept.
William Y. Yang, Mohammed Ben Issa, Fatma Saaoud, Keman Xu, Ying Shao, Yifan Lu, Waleska Dornas, Ramon Cueto, Xiaohua Jiang, Xiaohua Jiang, Hong Wang, Xiaofeng Yang, Xiaofeng Yang   +12 more
doaj   +1 more source

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development [PDF]

, 2011
The C-type lectin receptor CLEC-2 signals through a pathway that is critically dependent on the tyrosine kinase Syk. We show that homozygous loss of either protein results in defects in brain vascular and lymphatic development, lung inflation and ...
Abramoff, Abtahian, Alice Y. Pollitt, Aparicio-Vergara, Bertozzi, Bohmer, Brenda A. Finney, Caetano Reis e Sousa, Carramolino, Caton, Cecile Bénézech, Chagraoui, Cheng, Christou, Clausen, Colonna, Craig E. Hughes, Cueni, de Boer, Diego Mourao-Sa, Edina Schweighoffer, Francesca Barone, Gerard B. Nash, Gustafsson, Hodivala-Dilke, Hughes, Hughes, Humphreys, Ichise, Kate L. Lowe, Kaufmann, Kerrigan, Leyre Navarro-Núñez, Makinen, Martin-Villar, May, Mocsai, Mourao-Sa, Navarro, Navarro, Nicholas Smithers, Nieswandt, Pardridge, Ramirez, Saijo, Schacht, Sebzda, Spalton, Stacey A. Langan, Steve P. Watson, Steve Sheardown, Suzuki-Inoue, Suzuki-Inoue, Suzuki-Inoue, Suzuki-Inoue, Tammela, Tang, Tiedt, Tober, Turner, Uhrin, Victor L. J. Tybulewicz, Warburton, Watson, Williams, Xie, Xu   +66 more
core   +2 more sources

Renal Lymphatics: Anatomy, Physiology, and Clinical Implications

Frontiers in Physiology, 2019
Renal lymphatics are abundant in the cortex of the normal kidney but have been largely neglected in discussions around renal diseases. They originate in the substance of the renal lobule as blind-ended initial capillaries, and can either follow the main ...
P. Russell, Jiwon Hong, J. Windsor, M. Itkin, A. Phillips   +4 more
semanticscholar   +1 more source

Mesenteric Lymphatic Alterations Observed During DSS Induced Intestinal Inflammation Are Driven in a TLR4-PAMP/DAMP Discriminative Manner

Frontiers in Immunology, 2019
Background: Inflammatory bowel disease (IBD) is characterized by both acute and chronic phase inflammation of the gastro-intestinal (GI) tract that affect a large and growing number of people worldwide with little to no effective treatments.
Matthew Stephens, Shan Liao, Pierre-Yves von der Weid   +2 more
doaj   +1 more source

Zebrafish facial lymphatics develop through sequential addition of venous and non‐venous progenitors

EMBO Reports, 2019
Lymphatic vessels are known to be derived from veins; however, recent lineage‐tracing experiments propose that specific lymphatic networks may originate from both venous and non‐venous sources.
Tiffany C Y Eng, Wenxuan Chen, K. Okuda, June P Misa, Y. Padberg, Kathryn E. Crosier, P. Crosier, C. Hall, S. Schulte-Merker, Benjamin M. Hogan, J. Astin   +10 more
semanticscholar   +1 more source

Sphingosine-1-phosphate promotes the persistence of activated CD4 T cells in inflamed sites [PDF]

, 2017
Inflammation can be protective or pathogenic depending on context and timeframe. Acute inflammation, including the accumulation of CD4 T cells, accompanies protective immune responses to pathogens, but the presence of activated CD4 T cells at sites of ...
Ammit, Barnden, Brinkmann, Brown, Chimen, Cyster, Debes, Faust, Firestein, Fu, Garrod, Gibson, Han, Hochreiter-Hufford, Hugues, Jo, Karuppuchamy, Kitano, Ledgerwood, Liao, Limaye, Lindquist, Mackay, Mackay, Mammoto, Masopust, Matloubian, Matsuura, McInnes, Means, Mempel, Mendoza, Murphy, Nowarski, Olivera, Priceman, Pyne, Sawicka, Skon, Smith, Spangrude, Tarrason, Teijeira, Tsunemi, Veres, Wang, Wang   +46 more
core   +3 more sources