Results 91 to 100 of about 81,713 (355)

Morphological characterization of canine retrobulbar lymphoma [PDF]

open access: yesOpen Veterinary Journal, 2018
This report characterized seven cases of canine retrobulbar lymphoma that have been diagnosed during 2008 to 2014 by immunophenotyping of CD3 and Pax5. Classification of lymphoma were performed according to the revised WHO guidelines.
Natthanet Sritrakoon   +4 more
doaj   +1 more source

Modeling and Simulation to Inform Apixaban Dosing in Pediatrics With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Treated With Asparaginase

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Apixaban could be a potential treatment option for the prevention of venous thromboembolism (VTE) in children with acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LL). This analysis describes an updated two‐compartment population pharmacokinetic (PPK) model that characterizes the PK variability of apixaban in pediatric patients with ALL ...
Praneeth Jarugula   +14 more
wiley   +1 more source

Pediatric lymphoma may develop by "one-step" cell transformation of a lymphoid cell [PDF]

open access: yesarXiv, 2018
Lymphomas are a large group of neoplasms developed from lymphoid cells (LCs) in lymph nodes (LNs) or lymphoid tissues (LTs). Some forms of lymphomas, including Burkitt lymphoma (BL), ALK+ anaplastic large cell lymphoma (ALK+-ALCL), and T-cell lymphoblastic lymphoma/leukemia (T-LBL), occur mainly in children and teenagers.
arxiv  

Outcome of children and adolescents with lymphoblastic lymphoma [PDF]

open access: yesRevista da Associação Médica Brasileira, 2015
Summary Introduction: lymphoblastic lymphoma (LBL) is the second most common subtype of non-Hodgkin lymphoma in children. The aim of this study was to characterize the clinical course of children and adolescents with LBL treated at a tertiary center. Methods: this is a retrospective cohort study of 27 patients aged 16 years or younger with LBL admitted
Oliveira, Maria Christina Lopes Araújo   +5 more
openaire   +9 more sources

ESR1 Variants and Subcontinental Genomic Ancestry: Insights from the 1000 Genomes Project and Native American Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The ESR1 gene is relevant in breast cancer treatments in the pharmacogenetics context. However, Native, African, and mixed populations are known to be underrepresented in genomic studies. This is particularly important given that the difference in variants' frequencies among different populations can lead to population‐specific clinical implications ...
Mariana M. Scudeler   +11 more
wiley   +1 more source

Gum hypertrophy - an unusual presenting feature in a case of precursor T-cell acute lymphoblastic leukemia

open access: yesTurkish Journal of Hematology, 2008
Acute lymphoblastic leukemia/lymphoma, the malignant transformation of T-cell or B-cell precursors, is the most common diagnosis in pediatric oncology. Precursor T-cell acute lymphoblastic leukemia/lymphoma commonly affects adolescents, and is associated
Lingappa Appaji   +5 more
doaj  

Acute lymphoblastic leukemia may develop as a result of rapid transformation of a lymphoblast triggered by repeated bone-remodeling during bone-growth [PDF]

open access: yesarXiv, 2018
Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are two major forms of leukemia that arise from lymphoid cells (LCs). ALL occurs mostly in children and CLL occurs mainly in old people. However, the Philadelphia-chromosome-positive ALL (Ph+-ALL) and the Ph-like ALL occur in both children and adults.
arxiv  

Convolutional neural network with a hybrid loss function for fully automated segmentation of lymphoma lesions in FDG PET images [PDF]

open access: yesarXiv, 2022
Segmentation of lymphoma lesions is challenging due to their varied sizes and locations in whole-body PET scans. This work presents a fully-automated segmentation technique using a multi-center dataset of diffuse large B-cell lymphoma (DLBCL) with heterogeneous characteristics.
arxiv  

Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen   +12 more
wiley   +1 more source

Pulmonary function is a strong predictor of 2‐year overall survival and non‐relapse mortality after allogenic hematopoietic cell transplantation

open access: yesEuropean Journal of Haematology, Volume 110, Issue 1, Page 50-59, January 2023., 2023
Abstract Objectives The purpose of the study was to assess the validity of the hematopoietic cell transplantation‐specific comorbidity index (HCT‐CI) and of pulmonary comorbidity prior to HCT in terms of predicting non‐relapse mortality (NRM) and overall survival (OS).
Frederikke Schierbeck   +7 more
wiley   +1 more source

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