Results 101 to 110 of about 63,047 (307)

Genistein inhibited proliferation and induced apoptosis in acute lymphoblastic leukemia, lymphoma and multiple myeloma cells in vitro

, 2011
Genistein is one of the major isoflavones in soy products. It has been reported that genistein has apoptotic effects on certain hematological malignancies.
Li, Yuan, Lynn T. Frame, Karlene A. Hoo, Hoo, Karlene A., Nicholas D'Cunha, Cobos, Everardo, Frame, Lynn T., Cunha, Nicholas D', Wang Li, Everardo Cobos, Li, Wang, Yuan Li   +11 more
core   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

International Journal of Cancer, EarlyView.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley, Liesbet J. Van Eycken, Meredith E. Giuliani, Brian A. Rous, Shao Hui Huang, Hisao Asamura, Mary K. Gospodarowicz, Anne W. Lee, Brian O'Sullivan   +8 more
wiley   +1 more source

A case report of secondary B-cell acute lymphoblastic leukemia treated with a combination of FLT3 inhibitor and decitabine

Frontiers in Oncology
Secondary acute lymphoblastic leukemia (s-ALL) refers to acute lymphoblastic leukemia that occurs after a previous malignant tumor, including therapy-related acute lymphoblastic leukemia (t-ALL) and prior malignant tumor acute lymphoblastic leukemia (pm ...
Mengci Hu, Wenzhe Li, Pan Li, Jie Tan, Ya Wang, Ya Wang   +5 more
doaj   +1 more source

Epigenetic Activation of SOX11 in Lymphoid Neoplasms by Histone Modifications [PDF]

, 2011
Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem ...
Amador Virginia, Ott, G. (German), Royo Cristina, Palomero, J. (Jara), Agirre, Xabier, Salaverria Frigola, Itziar, Manel Esteller, Román-Gómez, José, Esteller, Manel, Balazs Balint, Andreas Rosenwald, Xargay-Torrent Silvia, Martín-Guerrero Idoia, Rosenwald, Andreas, Campo, E. (Elías), Pedro Jares, Royo Moreno, Cristina, Royo, Cristina, Hernández, Luis, Vegliante Maria Carmela, Rosenwald Andreas, Siebert, Reiner, Siebert Reiner, Martin-Guerrero, I. (Idoia), Balint, B. (Balazs), Jares, P. (Pedro), Calasanz María José, Prosper Felipe, Esteller Manel, Palomero Jara, Reiner Siebert, Agirre Xabier, Calasanz, María José, Bea Silvia, Roman-Gomez José, Vegliante, M.C. (Maria Carmela), Campo Elias, Silvia Bea, Lujambio, A. (Amaya), Beà Bobet, Sílvia M., Jose Calasanz, Maria, Roman-Gomez, J. (José), Vegliante, Maria Carmela, Maria Carmela Vegliante, María José Calasanz, Balint Balazs, Luis Hernandez, Enjuanes Anna, Enjuanes, A. (Anna), Felipe Prosper, Balint, Balazs, Martin-Subero, J.I. (Jose Ignacio), Salaverria, Itziar, Richter, Julia, Martín Guerrero, Idoia, Ott, German, Jares Gerboles, Pedro, Xargay-Torrent, S. (Silvia), Martín-Subero José I., Amaia Lujambio, Cristina Royo, José Roman-Gomez, José I Martín-Subero, Maria Carmela Vegliante, Martin-Guerrero, Idoia, Anna Enjuanes, Carmela Vegliante, Maria, Salaverria-Lete, I. (Itziar), Richter, J. (Julia), Esteller, M. (Manel), Martin-Subero, Jose I., Richter Julia, Bea, Silvia, Rosenwald, A. (Andreas), Xargay-Torrent, Silvia, Jares Pedro, Royo, C. (Cristina), Prosper-Cardoso, F. (Felipe), Campo Güerri, Elias, José I. Martín-Subero, Campo, Elias, Idoia Martín-Guerrero, Ott German, Calasanz-Abinzano, M.J. (Maria Jose), Lujambio, Amaia, Hernandez, L. (Luis), Palomero, Jara, Silvia Xargay-Torrent, Jares, Pedro, Hernandez Luis, Lujambio Amaia, Virginia Amador, German Ott, Jara Palomero, Bea, S. (Silvia), Elias Campo, Amador, V. (Virginia), Xargay i Torrent, Sílvia, Julia Richter, Salaverria Itziar, Siebert, R. (Reiner), Amador, Virginia, Enjuanes, Anna, Aguirre-Ena, X. (Xabier), Itziar Salaverria, Prosper, Felipe, Xabier Agirre   +106 more
core   +1 more source

Maternal Thyroid Diseases, Medication Use and Childhood Cancer Risks in Offspring: A Population‐Based Cohort Study in Denmark

International Journal of Cancer, EarlyView.
Thyroid diseases are common among women of reproductive age and may be related to childhood cancer, but the evidence is inconsistent. This study of childhood cancer with maternal thyroid diseases and medication use in a population‐based case‐control study using Danish registries found positive associations between maternal goiter and overall cancer ...
Chuanjie Deng, Kosuke Inoue, Chai Saechao, Johnni Hansen, Beate Ritz, Julia E. Heck   +5 more
wiley   +1 more source

Analysis of non-Hodgkin's lymphoma by conventional cytogenetics and fluorescence in-situ hybridisation. [PDF]

, 1995
Cytogenetic analysis was performed on 40 non-Hodgkin's lymphoma (NHQ node biopsies. Chromosomes X, 3 and 12 were the most frequently gained; of the much rarer monosomies, loss of chromosome 13 was most common.
Hammond, David William, Hammond, D.W.
core  

Post‐Translational Modifications of Key Proteins in Hematologic Malignancies: Carcinogenic Mechanisms, Biomarker Potential, and New Therapeutic Strategies

iLABMED, EarlyView.
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han, Chaowei Zhang, Weiyi Yao, Qing Hong, Xinyu Tang, Yanan Zhu, Na Chen   +6 more
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Pediatric T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma therapy

, 2009
T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in childhood are recognized to be two different pathologies with different biological basis and are treated according to different pediatric ...
R. Rondelli, PESSION, ANDREA, MASETTI, RICCARDO   +2 more
core   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source