Results 1 to 10 of about 75,449 (297)
Immunophenotyping: Analytical approaches and role in preclinical development of nanomedicines
Advanced Drug Delivery Reviews, 2022 Pharmaceutical products can activate immune cells, suppress their function, or change the immune responses to traditional immunologically active agonists such as those present in microbes. Therefore, the assessment of immunostimulation, immunosuppression,
Marina Dobrovolskaia
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Frontiers in Immunology, 2023 Various autoimmune diseases are characterized by distinct cell subset distributions and activation profiles of peripheral blood mononuclear cells (PBMCs). PBMCs can therefore serve as an ideal biomarker material, which is easily accessible and allows for
Teresa Preglej +5 more
doaj +2 more sources
OMIP‐044: 28‐color immunophenotyping of the human dendritic cell compartment
Cytometry Part A: the Journal of the International Society for Analytical Cytology, 2018 This work describes the first 30-parameter immunophenotyping of the human dendritic cell (DC) compartment using fluorescent-based flow cytometry. The optimized panel allows for simultaneous detection of 21 myeloid-centric markers distinguishing all ...
Florian Mair, Martin Prlic
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Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium [PDF]
Scientific Reports, 2016 AbstractStandardization of immunophenotyping requires careful attention to reagents, sample handling, instrument setup, and data analysis, and is essential for successful cross-study and cross-center comparison of data. Experts developed five standardized, eight-color panels for identification of major immune cell subsets in peripheral blood.
Greg Finak +33 more
openaire +6 more sources
Journal of Immunological Methods, 2018 Variability induced by delayed cell processing and cell cryopreservation presents unique challenges for immunophenotyping in large population studies. We conducted a pilot study to evaluate the effect of delayed cell processing and cryopreservation on ...
Eileen Crimmins +2 more
exaly +2 more sources
Standardizing immunophenotyping for the Human Immunology Project
Nature Reviews Immunology, 2012 The heterogeneity in the healthy human immune system, and the immunological changes that portend various diseases, have been only partially described. Their comprehensive elucidation has been termed the 'Human Immunology Project'.
Jp Mccoy +2 more
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A Practical Cryopreservation and Staining Protocol for Immunophenotyping in Population Studies
Current Protocols in Cytometry, 2018 Large population‐based cohort studies, through their prospective collection of a broad range of health information, represent an invaluable resource for novel insights into the pathogenesis of human diseases.
Eileen Crimmins +2 more
exaly +2 more sources
Application and interpretation of immunophenotyping data in safety and risk assessment
Frontiers in ToxicologyThe use of immunophenotyping during immunotoxicity investigations was first popularized in the 1980 s and has since become more integrated into diagnostic and non-clinical assessments.
Michael I Luster
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Microglia immunophenotyping in gliomas
Oncology Letters, 2017 Microglia, once assimilated to peripheral macrophages, in gliomas has long been discussed and currently it is hypothesized to play a pro-tumor role in tumor progression. Uncertain between M1 and M2 polarization, it exchanges signals with glioma cells to create an immunosuppressive microenvironment and stimulates cell proliferation and migration.
Annovazzi, Laura +5 more
openaire +4 more sources
Citation: 'immunophenotyping' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13309 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests
Herold NC, Zubair M, Mitra P.
europepmc +2 more sources