Results 1 to 10 of about 49,835 (287)

Impact of immunophenotyping on management of acute leukemias

Haematologica, 1999
BACKGROUND AND OBJECTIVE: The diagnosis of acute leukemias (AL) requires a multiparametric approach in order to apply risk-adapted therapeutic protocols and appreciate the potential outcome of any given patient.
MC Bene, M Bernier, G Castoldi, GC Faure, W Knapp, WD Ludwig, E Matutes, A Orfao, M van't Veer   +8 more
doaj   +1 more source

Immunological Markers of Cardiovascular Pathology in Older Patients

Biomedicines
Background: The aging process is accompanied by changes in the immunological status of a person. Immunosenescence is considered a significant cause of the development of cardiovascular diseases (CVD) in elderly people.
Akbota Bugibayeva, Almagul Kurmanova, Kuat Abzaliyev, Symbat Abzaliyeva, Gaukhar Kurmanova, Diana Sundetova, Merei Abdykassymova, Raushan Bitemirova, Ulzas Sagalbayeva, Karashash Absatarova, Madina Suleimenova   +10 more
doaj   +1 more source

Microglia immunophenotyping in gliomas

Oncology Letters, 2017
Microglia, once assimilated to peripheral macrophages, in gliomas has long been discussed and currently it is hypothesized to play a pro-tumor role in tumor progression. Uncertain between M1 and M2 polarization, it exchanges signals with glioma cells to create an immunosuppressive microenvironment and stimulates cell proliferation and migration.
Annovazzi, Laura, Mellai, Marta, Bovio, Enrica, Mazzetti, Samanta, Pollo, Bianca, Schiffer, Davide   +5 more
openaire   +3 more sources

HLA-E/Mtb specific CD4+ and CD8+ T cells have a memory phenotype in individuals with TB infection

Frontiers in Immunology
IntroductionTuberculosis (TB) is the deadliest infectious disease worldwide and novel vaccines are urgently needed. HLA-E is a virtually monomorphic antigen presentation molecule and is not downregulated upon HIV co-infection.
Linda Voogd, Catherine Riou, Catherine Riou, Thomas J. Scriba, Marjolein van Wolfswinkel, Krista E. van Meijgaarden, Kees L. M. C. Franken, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Tom H. M. Ottenhoff, Simone A. Joosten   +12 more
doaj   +1 more source

Extremely low viral reservoir in treated chronically HIV-1-infected individuals

EBioMedicine, 2020
Background: Small viral reservoirs are found predominantly in HIV-1 controllers and individuals treated during acute/early HIV-1 infection. However, other HIV+ individuals could naturally also harbour low viral reservoirs.
Cristina Gálvez, Victor Urrea, Judith Dalmau, Montse Jimenez, Bonaventura Clotet, Valérie Monceaux, Nicolas Huot, Lorna Leal, Victoria González-Soler, Maria González-Cao, Michaela Müller-Trutwin, Asier Sáez-Cirión, Felipe García, Julià Blanco, Javier Martinez-Picado, Maria Salgado   +15 more
doaj   +1 more source

P601: TP53 ANALYSIS AND REPORTING IN CHRONIC LYMPHOCYTIC LEUKAEMIA: ARE LABORATORIES IN COMPLIANCE WITH THE EUROPEAN RESEARCH INITIATIVE ON CLL (ERIC) RECOMMENDATIONS?

HemaSphere, 2022
A. Cartwright, S. Scott, L. Whitby
doaj   +1 more source

PB1854: NEXT GENERATION SEQUENCING APPROACHES IN CHRONIC LYMPHOCYTIC LEUKAEMIA: FINDINGS FROM EXTERNAL QUALITY ASSESSMENT

HemaSphere, 2022
A. Cartwright, H. Whitehouse, D. Travis, H. J. Clouston, S. Scott, L. Whitby   +5 more
doaj   +1 more source

Preservation of functionality, immunophenotype, and recovery of HIV RNA from PBMCs cryopreserved for more than 20 years

Frontiers in Immunology
BackgroundMany research laboratories have long-term repositories of cryopreserved peripheral blood mononuclear cells (PBMC), which are costly to maintain but are of uncertain utility for immunological studies after decades in storage.
Wayne B. Dyer, Wayne B. Dyer, Kazuo Suzuki, Angelique Levert, Mitchell Starr, Andrew R. Lloyd, John J. Zaunders   +6 more
doaj   +1 more source

Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease

Frontiers in Immunology, 2017
Chronic graft-versus-host disease (cGVHD) is a debilitating complication arising in around half of all patients treated with an allogeneic hematopoietic stem cell transplantation. Even though treatment of severe cGVHD has improved during recent years, it
Arwen Stikvoort, Yang Chen, Emelie Rådestad, Johan Törlén, Johan Törlén, Tadepally Lakshmikanth, Andreas Björklund, Jaromir Mikes, Adnane Achour, Adnane Achour, Jens Gertow, Berit Sundberg, Mats Remberger, Mikael Sundin, Mikael Sundin, Jonas Mattsson, Jonas Mattsson, Petter Brodin, Petter Brodin, Michael Uhlin, Michael Uhlin, Michael Uhlin   +21 more
doaj   +1 more source

Role of immunophenotypes in carcinoma breast

International Journal of Applied and Basic Medical Research, 2018
Nottingham's modification of Bloom-Richardson histopathological grading system (NGS) for carcinoma breast is a time-tested prognostic indicator; however, of lately, breast cancer has been evaluated through molecular techniques, particularly assessing the gene expression profiling and establishing molecular or immunophenotypes.
Shukla, Samarth, Acharya, Sourya, Vagha, Sunita, Dawande, Pratibha, Tamhane, Ankita   +4 more
openaire   +2 more sources