Results 251 to 260 of about 85,022 (329)

Prediction of B/T Subtype and ETV6–RUNX1 Translocation in Pediatric Acute Lymphoblastic Leukemia by Deep Learning Analysis of Giemsa‐Stained Whole Slide Images of Bone Marrow Aspirates

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Accurate determination of B/T‐cell lineage and the presence of the ETV6–RUNX1 translocation is critical for diagnosing acute lymphoblastic leukemia (ALL), as these factors influence treatment decisions and outcomes. However, these diagnostic processes often rely on advanced tools unavailable in low‐resource settings, creating a need
Arkadi Piven, Gil Shamai, Sarah Elitzur, Galit Pinto Berger, Yoav Binenbaum, Ron Kimmel, Ronit Elhasid   +6 more
wiley   +1 more source

Case Report: A rare pediatric case of B-cell lymphoblastic lymphoma presenting as an isolated renal mass with <i>EWSR1::FLI1</i> translocation and germline <i>CHEK2</i> variant. [PDF]

Front Pediatr
Daniels KP, Nichols KE, Pandey AS, Gheorghe G, Helmig S, Garrett K, Bag AK, Inaba H, Ribeiro R.   +8 more
europepmc   +1 more source

How I Approach Ethical Considerations for Pediatric Phase I CAR T‐Cell Trials

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Phase I trials of chimeric antigen receptor (CAR) T cells have shown remarkable promise in pediatric B‐cell malignancies. Such outcomes have shifted expectations for other phase I CAR T‐cell trials to have high response rates. The juxtaposition of high expectations, uncertain outcomes, and potential for life‐threatening toxicities raises ...
Sarah W. Peters, Sara K. Silbert, Elizabeth M. Holland, Annette Rid, Rayne H. Rouce, Christine Grady, Nirali N. Shah   +6 more
wiley   +1 more source

Retrospective analysis of clinical and molecular characteristics as prognostic factors in adult T-cell lymphoblastic lymphoma. [PDF]

Am J Cancer Res
Ma L, Wang J, Zhao J, Zheng M, Wen X, Su L.   +5 more
europepmc   +1 more source

Long‐Term Projections of Childhood Cancer Incidence and Prevalence in Ontario, Canada Until 2040

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background The prevalence of childhood cancer continues to rise due to increases in cancer incidence and advances in treatment, leading to better survival. We generated epidemiologic projections for childhood cancer, by cancer type, in Ontario, Canada, until 2040.
Alexandra Moskalewicz, Sumit Gupta, Petros Pechlivanoglou, Paul C. Nathan   +3 more
wiley   +1 more source

B-cell lymphoblastic lymphoma patient presenting with life threatening ruptured mycotic aneurysm of internal iliac artery. [PDF]

Radiol Case Rep
Malik M, Naveed MA, Asif MA, Siddique K, Kanwal U.   +4 more
europepmc   +1 more source

Effects of a Low Versus Moderate–High Intense Exercise Program on Innate Immune Recovery, Fitness, and Quality of Life During Pediatric Allo‐HSCT—The ANIMAL Exploratory Randomized Controlled Trial

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Objectives Pediatric cancer patients undergoing allogeneic hematopoietic stem cell transplantation (allo‐HSCT) are severely immunosuppressed leading to a high risk for life‐threatening infections. This trial investigates the effects of exercise during allo‐HSCT on immune cell recovery and patient‐related outcomes (DRKS00019865). Methods Twenty‐
Ronja Beller, Sabrina B. Bennstein, Dirk Reinhardt, Gabriele Gauß, Carolina Chamorra Vina, Helmut Hanenberg, Markus Uhrberg, Miriam Götte   +7 more
wiley   +1 more source

High-Dose Methotrexate in Children and Young Adults With ALL and Lymphoblastic Lymphoma: Results of the Randomized Phase III Study UKALL 2011. [PDF]

J Clin Oncol
Kirkwood AA, Goulden N, Moppett J, Samarasinghe S, Hough R, Rowntree C, Lawson S, Kearns P, Lawson A, Vora A.   +9 more
europepmc   +1 more source

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

Venetoclax combination with Cladribine, idarubicin, Cytarabine for relapsed T-Cell acute lymphoblastic leukemia/lymphoblastic lymphoma treatment: A case report and literature review. [PDF]

Leuk Res Rep
Yahia AE, Motabi I, Alsakkaf AA, Alzahrani K, Alsuhaibani LM, Albtoosh B, AlBathi AK, Alrajhi AM.   +7 more
europepmc   +1 more source