Results 231 to 240 of about 63,047 (307)

A Data‐Driven Redefinition of Early Relapse in Pediatric T Cell Acute Lymphoblastic Leukemia: Evidence for Progression of Disease 15 Months

open access: yesMed Research, Volume 2, Issue 2, Page 227-235, June 2026.
Data‐driven redefinition of early relapse in pediatric T‐ALL using hazard modeling, cumulative incidence, and time‐dependent HR across 1533 patients in three independent cohorts identifies 15 months as the optimal threshold. By integrating temporal risk metrics and external validation, this study provides evidence for POD ≤ 15 months as a data‐driven ...
Na Zhang   +6 more
wiley   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong   +4 more
wiley   +1 more source

Adult TWIST2‐high B‐ALL confirms metabolic association but reveals molecular heterogeneity

open access: yes
HemaSphere, Volume 10, Issue 6, June 2026.
Wencke Walter   +3 more
wiley   +1 more source

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu   +3 more
wiley   +1 more source

A rare case of precursor B-cell lymphoblastic lymphoma of the orbit in a child.

open access: yesOman J Ophthalmol
Jange RG   +5 more
europepmc   +1 more source

Development and validation of a nutrition risk screening for patients with childhood cancer in Brazil (NUTRICCAN)

open access: yesNutrition in Clinical Practice, Volume 41, Issue 3, Page 768-778, June 2026.
Abstract Background Diagnosing malnutrition in patients with pediatric cancer is challenging because tumor masses can interfere with anthropometric measurements. STRONGkids considers cancer a general risk factor, whereas Screening Tool for Childhood Cancer (SCAN) classifies patients as at risk or not, potentially missing those who need nutrition ...
Cristiane Ferreira Marçon   +2 more
wiley   +1 more source

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