Results 211 to 220 of about 270,921 (246)

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

Isocitrate Dehydrogenase (IDH) Mutations in Hematological Malignancies: Epidemiology, Mechanisms, and Therapeutic Strategies

MedComm – Future Medicine, Volume 5, Issue 3, September 2026.
IDH mutation is an important event in hematological malignancies. This review systematically integrates the basic mechanism of IDH mutations and combines it with the clinical translation of related research progress. It also discusses the application strategies of IDH inhibitors and feasible research directions, with the aim of providing a theoretical ...
Jinkun Xu, Haiying Bai, Lijuan Hu
wiley   +1 more source

Immune Checkpoint Inhibitors in Cancer Therapy: Clinical Landscape, Resistance Mechanisms, and Therapeutic Innovations

MedComm – Oncology, Volume 5, Issue 3, September 2026.
The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

The Journal of Pathology, Volume 270, Issue 1, Page 23-39, September 2026.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +1 more source

Differential in vivo tyrosine kinase inhibitor sensitivities of pediatric ABL‐class Ph‐like B‐acute lymphoblastic leukemia

HemaSphere, Volume 10, Issue 9, September 2026.
Ritul Sharma, Jackson K. Dardis, Huong Anh Mai, Camilo Arenas Merizalde, Cesca van de Ven, Diego A. Bárcenas López, Shubhmita Bhatnagar, Andishe Attarbaschi, Judith M. Boer, Monique L. den Boer, Sarah K. Tasian   +10 more
wiley   +1 more source

Not Too Young to Understand: Meaning Making From the Perspectives of School‐Aged Children With Cancer—A Scoping Review

Psycho-Oncology, Volume 35, Issue 9, September 2026.
ABSTRACT Background Meaning making is increasingly recognized as an important determinant of psychosocial adjustment in adult oncology. However, how school‐aged children make meaning of cancer and how developmental, relational, and sociocultural influences shape this process remain insufficiently characterized, particularly because frameworks are ...
Yixuan Wang, Cheng Jin, Jennifer Currin‐McCulloch, David MacPhee, Abby R. Rosenberg, Yijia Yang, Zhenrong Su, Peichen Liu, Jiameng Wang, Sydney Pryor   +9 more
wiley   +1 more source

A rare case of precursor B-cell lymphoblastic lymphoma of the orbit in a child.

Oman J Ophthalmol
Jange RG, Koka K, Krishnakumar S, Jayaraman D, Scott JX, Mukherjee B.   +5 more
europepmc   +1 more source

A case series of B-Lymphoblastic lymphoma with C-MYC rearrangement in children: diagnostic and therapeutic challenges. [PDF]

Ann Hematol
Yang X, Duan Y, Zhou C, Zhang N, Bai X, Jin L, Huang S, Zhang M.   +7 more
europepmc   +1 more source

Identification of favorable subgroups of pediatric high‐hyperdiploid acute lymphoblastic leukemia—A retrospective multinational study

HemaSphere, Volume 10, Issue 9, September 2026.
Andishe Attarbaschi, Amir Enshaei, Saskia Sonnenberg, Chloé Arfeuille, Draga Barbaric, Lena Behrman, Anke Bergmann, Nicole Bodmer, Judith M. Boer, Myriam Campbell, Gunnar Cario, Hélène Cavé, Lydia Champezou, Sarah Elitzur, Gabriele Escherich, Hester A. de Groot‐Kruseman, Monique L. den Boer, Csongor Kiss, Jelena Lazic, Anja Möricke, Hannah Muhle, Karin Nebral, Rob Pieters, Pierre Rohrlich, Martin Schrappe, Lucie Srámková, Ajay Vora, Emese Zsigrai, Arndt Borkhardt, Martin Zimmermann, Anthony V. Moorman, International Berlin‐Frankfurt‐Münster (i‐BFM) Study Group   +31 more
wiley   +1 more source

Catastrophic asparaginase-induced cerebral and systemic thrombosis in a young female with T-cell lymphoblastic lymphoma: A case report & literature review. [PDF]

Leuk Res Rep
Ahmed SAI, AlHanbali AS.
europepmc   +1 more source