Results 241 to 250 of about 99,740,226 (294)

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Transcriptomics-guided serum podoplanin and interpretable machine learning for early risk stratification of necrotizing enterocolitis in preterm infants. [PDF]

Front Immunol
Peng H, Liu X, Li Y, Zhou M, Bian J, Huang Y, Hu Z, Sun W, Zhu X.   +8 more
europepmc   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source

Clinical Impact of the C-Reactive Protein-Albumin-Lymphocyte Index as a Prognostic Biomarker in Patients With Recurrent Pancreatic Cancer. [PDF]

In Vivo
Sakamoto T, Urakami K, Uehira K, Yoshida J, Kishino M, Morimoto M, Murakami Y, Miyatani K, Shishido Y, Kihara K, Yamamoto M, Matsunaga T, Fujiwara Y.   +12 more
europepmc   +1 more source

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

Advanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang, Miaoyu Li, Tiantian Li, Xiaojie Zang, Haiyang Shi, Yaru Liu, Chengcheng Zhang, Jianxin Zhao, Qixiao Zhai, Wei Chen, Fengwei Tian   +10 more
wiley   +1 more source

Association between systemic inflammation and long-term mortality in emergency department patients with severe hypertension. [PDF]

Clinics (Sao Paulo)
Yoo B, Kim BS, Kim HJ, Shin JH.
europepmc   +1 more source

The C-reactive protein-albumin-lymphocyte index is associated with ventricular functional improvement and long-term outcomes after cardiac resynchronization therapy. [PDF]

Front Nutr
Zhang R, Duan Q, Lv X, Liu Y, Chen W, Yan Z, Liu J, Wang S, Zhao D, Zhao Q, Zhang W.   +10 more
europepmc   +1 more source

Lower Admission CALLY Index Is Associated with Contrast-Associated Acute Kidney Injury in Patients with STEMI Undergoing Primary PCI. [PDF]

Medicina (Kaunas)
Eynel E, Yılmaz D, Nyyazov A, Eynel E, Kocayiğit I, Aksoy MNM.   +5 more
europepmc   +1 more source

Prognostic value of systemic inflammatory markers in patients with malignancy-associated pulmonary thromboembolism: A retrospective observational study. [PDF]

Medicine (Baltimore)
Arslan Aksu E, Özdemir L, Gegin S, Özdemir B.   +3 more
europepmc   +1 more source

Systemic Inflammation and Colorectal Cancer: Assessing the Role of Reverse Causality. [PDF]

Cancers (Basel)
Safizadeh F, Gwenzi T, Mandic M, Hoffmeister M, Brenner H.   +4 more
europepmc   +1 more source