Results 1 to 10 of about 582,774 (269)
Frontiers in Immunology, 2023 IntroductionMHC class II molecules are essential for appropriate immune responses against pathogens but are also implicated in pathological responses in autoimmune diseases and transplant rejection.
Camilla Wibrand +12 more
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The Oncologist, 1999 Abstract Mechanisms in Hematology is a book with an accompanying interactive CD-ROM designed to assemble basic concepts that underlie clinical understanding and progress. It is presented as a concise text with a series of diagrams that distill diffuse information into a compact form.
L G, Israels, E D, Israels
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Generation of High Quality Memory B Cells
Frontiers in Immunology, 2022 Protection against pathogen re-infection is mediated, in large part, by two humoral cellular compartments, namely, long-lived plasma cells and memory B cells.
Takeshi Inoue +4 more
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Assessing the impact of an antigen-specific antibody response on atherosclerosis development in mice
STAR Protocols, 2023 Summary: The antibody immune response plays a critical role in atherosclerosis. Here, we present a protocol for assessing the impact of an antigen-specific germinal center antibody response on atherosclerosis development, using a pro-atherogenic mouse ...
Alberto Del Monte-Monge +3 more
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Antigen presentation by B cells enables epitope spreading across an MHC barrier
Nature Communications, 2023 Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus erythematosus (SLE)
Cecilia Fahlquist-Hagert +22 more
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Cell polarity regulators, multifunctional organizers of lymphocyte activation and function
Biomedical Journal, 2022 Cell polarity regulators are ubiquitous, evolutionary conserved multifunctional proteins. They contain a variety of protein–protein interaction domains endowing them the capacity to interact with cytoskeleton structures, membrane components and multiple ...
Marta Mastrogiovanni +2 more
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Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5
Cell Reports, 2020 Summary: The germinal center (GC) response is critical for generating high-affinity humoral immunity and immunological memory, which forms the basis of successful immunization. Control of the GC response is thought to require follicular regulatory T (Tfr)
Ine Vanderleyden +8 more
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Cell Reports, 2017 Adenomatous polyposis coli (APC) is a polarity regulator and tumor suppressor associated with familial adenomatous polyposis and colorectal cancer development.
Sonia Agüera-González +9 more
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Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination
Frontiers in Immunology, 2021 A functional adaptive immune system must generate enormously diverse antigen receptor (AgR) repertoires from a limited number of AgR genes, using a common mechanism, V(D)J recombination.
Carolyn H. Rogers +2 more
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Neutrophil-to-Lymphocyte, Platelet-to-Lymphocyte and Monocyte-to-Lymphocyte Ratio in Bipolar Disorder [PDF]
Brain Sciences, 2021 Background: Several inflammatory hypotheses have been suggested to explain the etiopathogenesis of bipolar disorder (BD) and its different phases. Neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), and monocyte-to-lymphocyte (MLR) ratios have been proposed as potential peripheral biomarkers of mood episodes.
Laura Fusar-Poli +8 more
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