Results 141 to 150 of about 1,230,088 (370)

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, Volume 15, Issue 5, Page 867-884, May 2025.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

FATE OF THE LYMPHOCYTE [PDF]

, 1921
C. H. Bunting, John H. Huston
openalex   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, Volume 15, Issue 5, Page 754-762, May 2025.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Technical challenges of intracellular flow cytometry-based assays as a functional complement to diagnosis of signaling defects of inborn errors of immunity: PI3K pathway as a case of study

Frontiers in Immunology
BackgroundThe use of next-generation sequencing in inborn errors of immunity (IEI) has considerably increased the identification of novel gene variants, many of which are identified in patients without the described clinical phenotype or with variants of
Lucía del Pino Molina, Keren Reche Yebra, Yolanda Soto Serrano, Álvaro Clemente Bernal, Carmen L. Avendaño-Monje, J. Gonzalo Ocejo-Vinyals, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, Rebeca Rodríguez Pena, Eduardo López Granados, Eduardo López Granados, Eduardo López Granados   +11 more
doaj   +1 more source

THE LYMPHOCYTE IN NATURAL AND INDUCED RESISTANCE TO TRANSPLANTED CANCER [PDF]

, 1920
James B. Murphy, Waro Nakahara
openalex   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, Volume 15, Issue 5, Page 836-855, May 2025.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Studies of Phagocytic Activity of Lymphocytes [PDF]

, 1957
B. J. Koszewski, C. W. EMERICK, D. R. DICUS   +2 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Functional insights of an uncommon hypomorphic variant in IL2RG as a monogenic cause of CVID-like disease with antibody deficiency and T CD4 lymphopenia

Frontiers in Immunology
BackgroundOver the last decade, the identification of hypomorphic variants in patients previously diagnosed with Common Variable Immunodeficiency (CVID) has led to the association of milder phenotypes with variants of the IL2RG gene that are usually ...
Andrea González-Torbay, Andrea González-Torbay, Keren Reche-Yebra, Álvaro Clemente-Bernal, Yolanda Soto Serrano, Luz Yadira Bravo-Gallego, Luz Yadira Bravo-Gallego, Almudena Fernández López, Almudena Fernández López, Rebeca Rodríguez-Pena, Rebeca Rodríguez-Pena, Rebeca Rodríguez-Pena, María Bravo García-Morato, María Bravo García-Morato, María Bravo García-Morato, Eduardo López-Granados, Eduardo López-Granados, Eduardo López-Granados, Lucía del Pino-Molina, Lucía del Pino-Molina   +19 more
doaj   +1 more source

Antibody in Lymphocytes from Hyperimmunized Rabbits [PDF]

, 1951
Allan J. Erslev
openalex   +1 more source