Optimizing Lymphocyte Detection in Breast Cancer Whole Slide Imaging through Data-Centric Strategies [PDF]
arXivEfficient and precise quantification of lymphocytes in histopathology slides is imperative for the characterization of the tumor microenvironment and immunotherapy response insights. We developed a data-centric optimization pipeline that attain great lymphocyte detection performance using an off-the-shelf YOLOv5 model, without any architectural ...
arxiv
eXclusive Autoencoder (XAE) for Nucleus Detection and Classification on Hematoxylin and Eosin (H&E) Stained Histopathological Images [PDF]
arXiv, 2018 In this paper, we introduced a novel feature extraction approach, named exclusive autoencoder (XAE), which is a supervised version of autoencoder (AE), able to largely improve the performance of nucleus detection and classification on hematoxylin and eosin (H&E) histopathological images.
arxiv
Cytochemical Studies of Glycogen Content of Lymphocytes in Lymphocytic Proliferations [PDF]
, 1958 W. J. Mitus +3 more
openalex +1 more source
Utilizing Automated Breast Cancer Detection to Identify Spatial Distributions of Tumor Infiltrating Lymphocytes in Invasive Breast Cancer [PDF]
arXiv, 2019 Quantitative assessment of Tumor-TIL spatial relationships is increasingly important in both basic science and clinical aspects of breast cancer research. We have developed and evaluated convolutional neural network (CNN) analysis pipelines to generate combined maps of cancer regions and tumor infiltrating lymphocytes (TILs) in routine diagnostic ...
arxiv
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
THE LYMPHOCYTE IN NATURAL AND INDUCED RESISTANCE TO TRANSPLANTED CANCER [PDF]
, 1920 James B. Murphy, Waro Nakahara
openalex +1 more source
Studies of Phagocytic Activity of Lymphocytes [PDF]
, 1957 B. J. Koszewski +2 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie +4 more
wiley +1 more source
Frontiers in ImmunologyBackgroundThe use of next-generation sequencing in inborn errors of immunity (IEI) has considerably increased the identification of novel gene variants, many of which are identified in patients without the described clinical phenotype or with variants of
Lucía del Pino Molina +11 more
doaj +1 more source
Antibody in Lymphocytes from Hyperimmunized Rabbits [PDF]
, 1951 Allan J. Erslev
openalex +1 more source