A diagnostic prediction model was established based on the clinical characteristics of multicenter children with Kawasaki disease in Xinjiang. [PDF]
Niu M +13 more
europepmc +1 more source
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source
Monitoring immune cell dynamics for potential prognostic biomarker of sepsis. [PDF]
Ma H +5 more
europepmc +1 more source
Immune Predictors of Radiotherapy Outcomes in Cervical Cancer
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang +8 more
wiley +1 more source
Comment on Kumarasamy et al. Prognostic Utility of Platelet-Lymphocyte Ratio, Neutrophil-Lymphocyte Ratio and Monocyte-Lymphocyte Ratio in Head and Neck Cancers: A Detailed PRISMA Compliant Systematic Review and Meta-Analysis. <i>Cancers</i> 2021, <i>13</i>, 4166. [PDF]
Tatsis D, Louizakis A, Cheva A.
europepmc +1 more source
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen +22 more
wiley +1 more source
Complete blood counts and their derived inflammatory markers with anal fistulas in male children: A retrospective case-control study. [PDF]
Ma HF +6 more
europepmc +1 more source
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han +10 more
wiley +1 more source
Prognostic Value of Inflammatory Biomarkers for Mortality in Intensive Care Patients with Acute Pulmonary Embolism: A Retrospective Observational Study. [PDF]
Zhou M +5 more
europepmc +1 more source

