LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Correlation Between CD38<sup>+</sup> Cell Levels and Pulmonary Tuberculosis Complicated with Diabetes Mellitus: A Retrospective Analysis Based on Lymphocyte Subsets and Clinical Features. [PDF]
Wang Y, Mao W, Xu L, Xu W.
europepmc +1 more source
Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source
KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao +9 more
wiley +1 more source
Comparison of the prognostic value of different inflammation-based scores in patients with hepatocellular carcinoma after Lenvatinib therapy. [PDF]
Wu WJ +7 more
europepmc +1 more source
Systemic inflammatory markers in gastric ulcer: Leveraging routine blood tests. [PDF]
Zhang JW.
europepmc +1 more source
Clinical analysis of the onset characteristics and inducing factors of atypical renal tuberculosis. [PDF]
Li C, Liu J, Zhu G, Wang Q, Li W.
europepmc +1 more source
Relationship Between Lymphocyte-Associated Inflammatory Markers and Post-Stroke Cognitive Impairment
Qianying Hu +8 more
openalex +2 more sources

