Results 31 to 40 of about 1,723,798 (355)

The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases

open access: yesAnnals of Laboratory Medicine, 2019
The platelet-to-lymphocyte ratio (PLR) has emerged as an informative marker revealing shifts in platelet and lymphocyte counts due to acute inflammatory and prothrombotic states.
A. Gasparyan   +4 more
semanticscholar   +1 more source

A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo [PDF]

open access: yes, 2012
In vivo imaging has revolutionized understanding of the spatiotemporal complexity that subserves the generation of successful effector and regulatory immune responses.
Andrea J. White   +40 more
core   +2 more sources

Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor [PDF]

open access: yes, 2018
derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focussed on
A Augello   +69 more
core   +2 more sources

What is the normal value of the neutrophil-to-lymphocyte ratio?

open access: yesBMC Research Notes, 2017
Neutrophil-to-lymphocyte ratio (NLR) has proven its prognostic value in cardiovascular diseases, infections, inflammatory diseases and in several types of cancers. However, no cut-off has been proposed on the basis of reference values coming from healthy
P. Forget   +5 more
semanticscholar   +1 more source

A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study [PDF]

open access: yes, 2006
Objective: The objective of the trial was to evaluate in a pilot setting the safety and efficacy of interleukin-2 (IL-2) therapy when used without concomitant antiretroviral therapy as a treatment for HIV infection.
Abrams   +44 more
core   +2 more sources

Initiation of HIV therapy [PDF]

open access: yes, 2010
In this paper, we numerically show that the dynamics of the HIV system is sensitive to both the initial condition and the system parameters. These phenomena imply that the system is chaotic and exhibits a bifurcation behavior.
BINGO WING-KUEN LING   +2 more
core   +1 more source

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity

open access: yeseLife, 2018
Wiskott-Aldrich syndrome (WAS) is an immune pathology associated with mutations in WAS protein (WASp) or in WASp interacting protein (WIP). Together with the small GTPase Cdc42 and other effectors, these proteins participate in the remodelling of the ...
Marianne Burbage   +8 more
doaj   +1 more source

The effects of splenic irradiation on lymphocyte subpopulations in chronic B-lymphocytic leukemia [PDF]

open access: yes, 1988
We describe the effect of splenic irradiation (SI) (0,5–1 Gy weekly) on lymphocyte subpopulations for 7 patients with progressive B chronic B-lymphocytic leukemia (B-CLL).
Aabo   +24 more
core   +3 more sources

Coordinating Cytoskeleton and Molecular Traffic in T Cell Migration, Activation, and Effector Functions

open access: yesFrontiers in Cell and Developmental Biology, 2020
Dynamic localization of receptors and signaling molecules at the plasma membrane and within intracellular vesicular compartments is crucial for T lymphocyte sensing environmental cues, triggering membrane receptors, recruiting signaling molecules, and ...
Marta Mastrogiovanni   +4 more
doaj   +1 more source

Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint

open access: yesCell Reports, 2021
Summary: T lymphocyte differentiation in the steady state is characterized by high cellular turnover whereby thymocytes do not self-renew. However, if deprived of competent progenitors, the thymus can temporarily maintain thymopoiesis autonomously.
Rafael A. Paiva   +6 more
doaj   +1 more source

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