Results 61 to 70 of about 944,351 (214)
Cell Reports, 2018 Summary: Wiskott-Aldrich syndrome protein (WASp) is a main cytoskeletal regulator in B cells. WASp-interacting protein (WIP) binds to and stabilizes WASp but also interacts with actin.
Selina Jessica Keppler +8 more
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In-vitro demonstration of cell-mediated immunity to vaccinia virus in man [PDF]
, 1975 Cell mediated immunity to vaccinia virus in man was studied by lymphocyte transformation. Vaccinia antigen, propagated on BHK-21 and Vero cells, could be used successfully for in-vitro testing after partial purification as well as crude infectious ...
Koszinowski, Ulrich H. +2 more
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Dynamic reorganisation of intermediate filaments coordinates early B-cell activation
Life Science Alliance, 2018 This study examines the role of vimentin, a type III intermediate filament, in B-cell function using a combination of in vitro and in vivo assays, including super-resolution microscopic techniques.
Carlson Tsui +7 more
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Nature Communications, 2020 Epigenetic information is transmitted from mother to daughter cells through mitosis. Here, the authors isolate native chromosomes from metaphase-arrested cells and perform LC-MS/MS to identify chromosome-bound proteins in pluripotent stem cells during ...
Dounia Djeghloul +19 more
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Preserved cellular immunity in smoldering acute leukemia [PDF]
, 1976 "Smoldering acute leukemia", a variant of acute myelogenous leukemia, has been recognized with frequent incidence in recent years. This is chracterized by benign clinical course, poor physical findings, leukopenia and mild anemia in the ...
Toki, Hironobu
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New Insights into Epigenetic Regulation of T Cell Differentiation
Cells, 2021 Immature CD4− CD8− thymocytes progress through several developmental steps in the thymus, ultimately emerging as mature CD4+ (helper) or CD8+ (cytotoxic) T cells.
Avik Dutta +2 more
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Cell Reports, 2015 Jarid2 is part of the Polycomb Repressor complex 2 (PRC2) responsible for genome-wide H3K27me3 deposition. Unlike other PRC2-deficient embryonic stem cells (ESCs), however, Jarid2-deficient ESCs show a severe differentiation block, altered colony ...
David Landeira +13 more
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Frontiers in Immunology, 2023 IntroductionInborn errors of immunity (IEI) are an expanding group of rare diseases whose field has been boosted by next-generation sequencing (NGS), revealing several new entities, accelerating routine diagnoses, expanding the number of atypical ...
L. del Pino-Molina +17 more
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CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors [PDF]
, 1988 The ability of memory T lymphocytes derived from latently infected mice to control murine cytomegalovirus disease in the immunocompromised host was studied by adoptive transfer experiments.
Jonjic, Stipan +4 more
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Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes [PDF]
, 1990 Although the relative contribution of different immune effector functions to clearing tissues of cytomegalovirus is controversial, the contribution of CD8+ T lymphocytes has generally been accepted as essential. In this report, we show that under certain
Jonjic, Stipan +4 more
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