Results 101 to 110 of about 328,983 (310)

Quantifying tumour-infiltrating lymphocyte subsets : a practical immuno-histochemical method [PDF]

, 2007
Background: Efficient histological quantification of tumour-infiltrating T and B lymphocyte (TIL) subsets in archival tissues would greatly facilitate investigations of the role of TIL in human cancer biology. We sought to develop such a method. Methods:
Alison J. Gray, Bland, Brey, David I. Stott, Guillery, Hussein, Hussein, James J. Going, Liyanage, Matkowskyj, Mufson, Paula M. Loughlin, Poynton, Royet, Ruifrok, Sangwine, Timothy G. Cooke, von Bartheld, W. David George, Willimsky   +19 more
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Safety monitoring of the newer disease modifying therapies in multiple sclerosis patients in Mater Dei hospital [PDF]

, 2016
Patients with highly active Multiple Sclerosis can be started on the newer pharmaceutical agents, Dimethyl Fumarate or Fingolimod. Safety monitoring recommended includes regular blood analysis and also ophthalmic tests and MRI scans in the case of ...
Aquilina, Josanne, Zammit, Daniela
core  

The effect of pegbovigrastim on circulating neutrophil count in dairy cattle : a randomized controlled trial [PDF]

, 2018
Previous research in various species has shown that granulocyte-colony stimulating factor stimulates the production and release of neutrophils from bone marrow.
Bogado Pascottini, Osvaldo Américo, Carrier, J, LeBlanc, SJ, Van Schyndel, SJ   +3 more
core   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Analisis Kuantitas dan Hitung Jenis Leukosit pada Petugas Radiologi di Balai Besar Kesehatan Paru Masyarakat (Bbkpm) Makassar [PDF]

, 2017
The Radiology Officer is one of the groups that has a risk to the danger of radiation exposure and it caused of the healthy in the certain level. Then, it could cause the Chronis disease until with the death.
Armah, Z. (Zulfian), Naim, N. (Nurlia), Suciyani, S. (Suciyani)   +2 more
core  

Safety and immunogenicity of H1/IC31®, an adjuvanted TB subunit vaccine, in HIV-infected adults with CD4+ lymphocyte counts greater than 350 cells/mm3: a phase II, multi-centre, double-blind, randomized, placebo-controlled trial. [PDF]

, 2014
BACKGROUND: Novel tuberculosis vaccines should be safe, immunogenic, and effective in various population groups, including HIV-infected individuals. In this phase II multi-centre, double-blind, placebo-controlled trial, the safety and immunogenicity of ...
Andersen, Peter, Bang, Peter, Beattie, Trevor, Churchyard, Gavin J., Daubenberger, Claudia, Fielding, Katherine L., Gardiner, Nicolene, Hanekom, Willem A., Hoff, Søren T., Hughes, Elisabeth J., Jeffery, Hannah, Kagina, Benjamin M., Katsoulis, Lynn, Kromann, Ingrid, Landay, Alan, Lenz, Nicole, Mfinanga, Elirehema, Pohl, Christian, Reither, Klaus, Said, Khadija, Scriba, Thomas J.   +20 more
core   +5 more sources

Let us think about lymphocyte counts! [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2012
In this issue of our journal, our colleagues Juliane Morando, Sergio Costa Fortier, Ricardo Pasquini, Jose Zanis Neto and Carmem Maria Sales Bonfim from the Bone Marrow Transplantation Unit of the Hospital de Clinicas, Universidade Federal do Parana describe an interesting retrospective study of 137 under 21-year-old acute leukemia patients accumulated
openaire   +6 more sources

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Monitoring trends in the absolute lymphocyte count and the neutrophil-to-lymphocyte ratio in patients with breast cancer receiving eribulin

BMC Cancer
Background Studies have shown that the absolute lymphocyte count (ALC) and the neutrophil-to-lymphocyte ratio (NLR) are related to the outcomes in patients with breast cancer receiving specific chemotherapies.
Meng-Xia Su, Hsiang-Wen Lin, Hanh T. H. Nguyen, Tien-Chao Lin, Chih-Jung Chen, Hwei-Chung Wang, Chen-Teng Wu, Yao-Chung Wu, Geng-Yan He, Liang-Chih Liu, Chih-Hao Huang   +10 more
doaj   +1 more source