Results 111 to 120 of about 333,907 (356)
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host [PDF]
Purpose: In patients with colorectal cancer (CRC), a high-density local inflammatory infiltrate response is associated with improved survival, whereas elevated systemic inflammatory responses are associated with poor survival.
Clark, Jennifer +7 more
core +1 more source
Let us think about lymphocyte counts! [PDF]
In this issue of our journal, our colleagues Juliane Morando, Sergio Costa Fortier, Ricardo Pasquini, Jose Zanis Neto and Carmem Maria Sales Bonfim from the Bone Marrow Transplantation Unit of the Hospital de Clinicas, Universidade Federal do Parana describe an interesting retrospective study of 137 under 21-year-old acute leukemia patients accumulated
openaire +6 more sources
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
Few laboratories in resource-constrained countries can afford to perform laboratory-monitoring tests required for the management of HIV therapy. The initiation of an antiretroviral therapy is based on CD4+ count less than 350 cells/mm3according to the ...
Onuigwe, F.U., Alimi, R., Balarabe, I., Uko, E., Uchechukwu, N.J., Erhabor, O.
doaj
To examine the association between lymphocyte count trajectories and clinical outcomes in patients with spontaneous intracerebral hemorrhage (ICH) using data from the MIMIC-IV database.
Zongren Zhao +3 more
doaj +1 more source
Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico +8 more
core +1 more source

