Central Dysmyelination in SSADH‐Deficient Humans and Mice
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer+11 more
wiley +1 more source
Total Blood Lymphocyte Count Alteration During and after Pregnancy
Objective: To investigate the impact of gestational changes on blood lymphocyte count in healthy pregnancies. Study Design: This retrospective study is consisted of 108 consecutive normal pregnancies who delivered at our department in December 2015 ...
Gökçen Örgül+4 more
doaj +1 more source
Using CD4 lymphocyte count to predict survival with HIV infection [PDF]
V Harindra
openalex +1 more source
Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report
ABSTRACT HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who experienced worsening spastic paraparesis and neurogenic bladder dysfunction.
Jiahui Zeng+5 more
wiley +1 more source
Absolute lymphocyte and neutrophil counts in neonatal ischemic brain injury
Objectives: This study aimed to identify differences in absolute neutrophils, lymphocytes, and neutrophil-to-lymphocyte ratio between neonates with two forms of ischemic brain injury, hypoxic-ischemic encephalopathy, and acute ischemic stroke, compared ...
Jessica M Povroznik+3 more
doaj +1 more source
CD4 and total lymphocyte counts as predictors of HIV disease progression [PDF]
Frank A. Post, Robin Wood, Gary Maartens
openalex +1 more source
Time trends and predictors of gout remission over six years
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah+5 more
wiley +1 more source
Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog. [PDF]
BackgroundEvolution of indolent to aggressive lymphoma has been described in dogs but is difficult to distinguish from the de novo development of a second, clonally distinct lymphoma.
Bienzle, Dorothee+6 more
core +1 more source
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang+8 more
wiley +1 more source
CD4 Lymphocyte Counts and Mortality in AIDS Patients Requiring Mechanical Ventilator Support due to Pneumocystis carinii Pneumonia [PDF]
Sunil D. Kumar, Bruce P. Krieger
openalex +1 more source