Background Dasatinib, which is used to treat treating chronic myeloid leukemia, induces increases in blood lymphocytes during the treatment. In addition, neutrophil–lymphocyte count ratio (NLR) is associated with the related to development of chronic ...
Hirokazu Nakayama +3 more
doaj +1 more source
Predictive value of lymphocytopenia and the neutrophil-lymphocyte count ratio for severe imported malaria [PDF]
Background: Lymphocytopenia has frequently been described in patients with malaria, but studies on its association with disease severity have yielded conflicting results. The neutrophil/lymphocyte count ratio (NLCR) has been introduced as a parameter for
De Mendonça Melo, M. (Mariana) +7 more
core +1 more source
Relative lymphocyte count as an indicator of 3-year mortality in elderly people with severe COPD
Background Prognostic stratification of elderly patients with chronic obstructive pulmonary disease (COPD) is difficult due to the wide inter-individual variability in the course of the disease.
Domenico Acanfora +11 more
doaj +1 more source
Leucocytes, especially neutrophils featuring pro- and anti-cancerous characteristics, are involved in nearly every stage of tumorigenesis. Phenotypic and functional differences among mature and immature neutrophil fractions are well reported, and their ...
Rana Zeeshan Haider +3 more
doaj +1 more source
Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting [PDF]
Background: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior ...
Buchan, Keith G. +9 more
core +1 more source
Performance Evaluation of High Fluorescence Lymphocyte Count: Comparability to Atypical Lymphocyte Count and Clinical Significance [PDF]
To investigate the association between high-fluorescence lymphocyte cell (HFLC) and atypical lymphocyte (AL) counts, and to determine the clinical significance of HFLC.We compared automated HFLC and microscopic AL counts and analyzed the findings. Patient clinical data for each specimen were reviewed.A total of 320 blood specimens were included.
Chaicharoen Tantanate, Cherdsak Klinbua
openaire +2 more sources
CD4+ T-Lymphocyte Count/CD8+ T-Lymphocyte Count Ratio: Surrogate for HIV Infection in Infants? [PDF]
Early diagnosis and treatment is necessary to prevent HIV-infected infants progressing to AIDS. Antibody testing is not confirmatory before the age of 18 months and PCR not widely available in resource-poor settings. We studied the accuracy of CD4(+) T-lymphocyte count, CD4% and CD4/CD8 ratio as surrogate markers of infant HIV infection.Two hundred and
Navaneethapandian, P. G. D. +5 more
openaire +3 more sources
Effect of dimethyl fumarate on lymphocyte subsets in patients with relapsing multiple sclerosis
Background In patients treated with dimethyl fumarate, absolute lymphocyte count decline typically occurs during the first year and then plateaus; early drops have been associated with the development of severe prolonged lymphopenia.
Guy Buckle +15 more
doaj +1 more source
CD4 LYMPHOCYTE IN HIV / AIDS BEFORE AND AFTER ANTIRETROVIRAL THERAPY
: Human Immunodefficiency Virus (HIV) is a virus that decreases the human immunity system, therefore the infected people become susceptible to any kind of infections.
Rangsang Bagus Prabowo +2 more
doaj +1 more source
Immune compromise in HIV-1/HTLV-1 coinfection with paradoxical resolution of CD4 lymphocytosis during antiretroviral therapy: a case report [PDF]
Human immunodeficiency virus type-1 (HIV-1) and human T lymphotropic virus type-1 (HTLV-1) infections have complex effects on adaptive immunity, with specific tropism for, but contrasting effects on, CD4 T lymphocytes: depletion with HIV-1, proliferation
Bangham, C +6 more
core +2 more sources

