Clinical study of T lymphocyte subsets and several biological indicators in children with transient synovitis. [PDF]
Wang Y +7 more
europepmc +1 more source
Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Bifidobacterium ameliorates lupus nephritis and modulates aberrant differentiation of lymphocyte subsets. [PDF]
Wu L +6 more
europepmc +1 more source
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li +14 more
wiley +1 more source
Preoperative peripheral blood lymphocyte subsets integrated with geriatric nutritional risk index for prognostic assessment in elderly colorectal carcinoma patients. [PDF]
Wang Y, Hao Y, Jia H.
europepmc +1 more source
Geriatric asthmatics exhibit more comorbidities, poorer lung function, higher neutrophil ratios, and elevated CRP levels. ABSTRACT Objective The research analyzed the clinical characteristics of geriatric and nongeriatric asthma cases, aiming to provide new insights into the diagnosis and management of geriatric asthma for clinicians.
Mengxia Gu +4 more
wiley +1 more source
Reference Values for Extended Lymphocyte Subsets in Korean Children: A Multicenter Study Using the EuroFlow PIDOT Panel. [PDF]
Shin KH, Choi HW, Lim J, Kang ES.
europepmc +1 more source
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura +9 more
wiley +1 more source
Significant alterations in peripheral lymphocyte subsets and immune-related protein profiles in patients with periprosthetic joint infection. [PDF]
Li Z +7 more
europepmc +1 more source
ABSTRACT Background Deficient mismatch repair/microsatellite instability‐High (dMMR/MSI‐H) colorectal cancer (CRC) generally confers a favorable survival yet is paradoxically enriched for poorly differentiated (Por) histology, which is linked to aggressive behavior.
Tomoyuki Momma +9 more
wiley +1 more source

