Results 201 to 210 of about 745,482 (386)

Anaplastic large cell lymphoma: clinicopathological and immunohistochemical study of 20 cases classified according to the 2016 revision of the World Health Organization classification of lymphoid neoplasms [PDF]

, 2018
Diana Brisa Sevilla-Lizcano, Carlos Ortiz‐Hidalgo   +1 more
openalex   +1 more source

Supplementary Table from Post-transplant Malignancies Show Reduced T-cell Abundance and Tertiary Lymphoid Structures as Correlates of Impaired Cancer Immunosurveillance

, 2023
Rabi R. Datta, Simon Schran, Oana‐Diana Persa, Claire Aguilar, Martin Thelen, Jonas Lehmann, María A. García-Márquez, Kerstin Wennhold, Ella Preugszat, Peter Zentis, Michael S. von Bergwelt‐Baildon, Alexander Quaas, Christiane J. Bruns, Christine Kurschat, Cornelia Mauch, Heike Löser, Dirk L. Stippel, Hans Schlößer   +17 more
openalex   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Cyclin D1/PRAD1/BCL‐1 alternative transcript [B] protein product in B‐lymphoid malignancies with t(11;14)(q13;q32) translocation [PDF]

, 1999
Yoshitaka Hosokawa, Tatsuroh Joh, Yumiko Maeda, Andrew Arnold, Masao Seto   +4 more
openalex   +1 more source

203 Immune-mesenchymal crosstalk contribute to the expansion of autoreactive plasma cells in the tertiary lymphoid structures in Hidradenitis Suppurativa [PDF]

, 2023
W. Yu, John Barrett, Michelle Lin, Meaghan Marohn, Jason Devlin, A. Harrera, Juliana Remark, James G. Krueger, Kelly V. Ruggles, Sergei B. Koralov, Ernest S. Chiu, Ping Lu   +11 more
openalex   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Pulmonary Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue Associated with Granulomatous Inflammation in a Child with Chromosome 22q11.2 Deletion Syndrome (DiGeorge Syndrome)

, 2012
Tawatchai Pongpruttipan, James Cook, Miguel Reyes‐Múgica, Jonathan E. Spahr, Steven H. Swerdlow   +4 more
openalex   +2 more sources

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Histomolecular Features of a Rare Subtype of Pleomorphic Adenoma Characterised by Abundant Lymphoid Stroma and HMGA2 Rearrangements. [PDF]

Head Neck Pathol
Alsugair Z, Momenkhan S, Donzel M, Descotes F, Pissaloux D, Paindavoine S, Houlier A, Tirode F, Alix E, Mauduit C, Lopez J, Traverse-Glehen A, Céruse P, Philouze P, Champagnac A, Costes-Martineau V, Kikuchi Y, Uozaki H, Vaz E, Castain C, Benzerdjeb N.   +20 more
europepmc   +1 more source