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Trends in Immunology, 2012
Lymphoid organs are integral parts of all vertebrate adaptive immune systems. Primary lymphoid tissues exhibit a remarkable functional dichotomy: T cells develop in specialized thymopoietic tissues located in the pharynx, whereas B cells develop in distinct areas of general hematopoietic areas, such as the kidney or bone marrow.
Boehm, Thomas+2 more
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Lymphoid organs are integral parts of all vertebrate adaptive immune systems. Primary lymphoid tissues exhibit a remarkable functional dichotomy: T cells develop in specialized thymopoietic tissues located in the pharynx, whereas B cells develop in distinct areas of general hematopoietic areas, such as the kidney or bone marrow.
Boehm, Thomas+2 more
openaire +5 more sources
1974
The role of the respiratory tract in the defense against potential pathogens has been a subject of interest to microbiologists, virologists and immunologists for many years. The description of the secretory IgA system, common to mucosal surfaces throughout the body, has extended the interests of immunologists in the mechanisms of mucosal resistance (1).
R. L. Clancy+3 more
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The role of the respiratory tract in the defense against potential pathogens has been a subject of interest to microbiologists, virologists and immunologists for many years. The description of the secretory IgA system, common to mucosal surfaces throughout the body, has extended the interests of immunologists in the mechanisms of mucosal resistance (1).
R. L. Clancy+3 more
openaire +2 more sources
1987
The cells of the lymphoid tissues primarily involved in the generation of specific immune responses are the lymphocytes. As well as the lymphocytes, cells of the monocyte-macrophage series, which are collectively called accessory cells (ACs) are essential for generation of both cellular and humoral (antibody) responses.
Ian J. Forbes, Anthony S-Y. Leong
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The cells of the lymphoid tissues primarily involved in the generation of specific immune responses are the lymphocytes. As well as the lymphocytes, cells of the monocyte-macrophage series, which are collectively called accessory cells (ACs) are essential for generation of both cellular and humoral (antibody) responses.
Ian J. Forbes, Anthony S-Y. Leong
openaire +2 more sources
T cell immunity in lymphoid and non-lymphoid tissues
Current Opinion in Immunology, 2002Immune responses to infection or effective vaccination generally result in the development of memory lymphocytes capable of mounting a rapid response to secondary infection. Since most infections initiate in non-lymphoid tissues, defense at these sites may be important for protection.
Leo Lefrançois, David Masopust
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Macrophage heterogeneity in lymphoid tissues
Seminars in Immunopathology, 2013Macrophages in lymphoid organs exhibit a wide variety of phenotypes and functions. These cells excel in the removal of apoptotic cells that arise during the generation of immune cells and are thereby essential for the prevention of auto-immune responses.
den Haan, J.M.M., Martinez-Pomares, L.
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Nasal lymphoid tissue in the rat
Cell And Tissue Research, 1989The structure and organization of paired lymphoid tissue in the nasal mucosa, situated in the transitional zone on both sides of the septal opening of the pharyngeal duct, of conventionally-housed rats was examined by light microscopy and scanning and transmission electron microscopy.
J.P. Bruijntjes+3 more
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Trends in Immunology
To surveil an organ for pathogens, lymphoid structures need to sample antigens locally. The full set of lymphoid structures involved in surveilling for brain-tropic pathogens has not been defined. Through comprehensive imaging of the mouse meninges, a new study by Fitzpatrick et al. describes dural-associated lymphoid tissue (DALT) and its contribution
Nikhita Kirthivasan, Jason G. Cyster
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To surveil an organ for pathogens, lymphoid structures need to sample antigens locally. The full set of lymphoid structures involved in surveilling for brain-tropic pathogens has not been defined. Through comprehensive imaging of the mouse meninges, a new study by Fitzpatrick et al. describes dural-associated lymphoid tissue (DALT) and its contribution
Nikhita Kirthivasan, Jason G. Cyster
openaire +2 more sources
Nephrin in human lymphoid tissues
Cellular and Molecular Life Sciences CMLS, 2006When nephrin, the protein product of NPHS1, was cloned, it was proposed to be specific for the kidney glomerular podocytes. Recently, however, new reports have emerged verifying additional nephrin expression sites, particularly the insulin-producing beta cells of the pancreas, as well as the central nervous system. In this study, we demonstrate nephrin
Eva Åström+6 more
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Hematopoietic and Lymphoid Tissues
2012The hematopoietic and lymphoid tissues are found throughout the body and function to produce red blood cells, platelets, and white blood cells including inflammatory cells that react to various stimuli, such as infectious agents, traumatic injury, and other various conditions.
Michael Linden+2 more
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