Results 261 to 270 of about 375,061 (357)

OMIP‐115: High‐Dimensional Phenotypic Characterization of Human Natural Killer Cells for Therapeutic Use

open access: yesCytometry Part A, EarlyView.
ABSTRACT This 29‐color flow cytometry panel was developed and optimized for in‐depth characterization of human peripheral blood NK cells for preclinical development and monitoring of NK cell therapies. The panel includes markers associated with NK cell differentiation, cytotoxicity, tissue residency, as well as NK cell dysfunction.
Emil Birch Christensen   +4 more
wiley   +1 more source

Frequency and stability of populations of CD4+ and CD4+CD25+Foxp3+CD127lo Treg in healthy adults defined by cytometry using monoclonal antibodies to T cell associated molecules

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Monitoring subpopulations of CD4+ T cells in blood, especially regulatory CD4+CD25+Foxp3+CD127loT cells, has the potential to identify tolerance to transplants and defects that cause autoimmunity. CD45RA is expressed by naïve/resting CD4+, not by activated cells.
Nirupama D. Verma   +7 more
wiley   +1 more source

A 20‐color 21‐antigen flow cytometric assay for disease monitoring of T‐cell lymphoblastic leukemia

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract T‐lineage acute lymphoblastic leukemia (T‐ALL) is an aggressive neoplasm of immature T cells. Flow cytometry plays a critical role in the diagnosis and management of the disease. It is used to establish the abnormal immature T‐cell phenotype and to distinguish the early T‐cell precursor (ETP)‐ALL from more mature types at diagnosis.
Qi Gao   +8 more
wiley   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

Langerhans Cells: Sentinels of Skin Associated Lymphoid Tissue

open access: bronze, 1980
Galen B. Toews   +2 more
openalex   +1 more source

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