Results 281 to 290 of about 375,831 (354)

Peste des petits ruminants virus virulence is associated with an early inflammatory profile in the tonsils and cell cycle arrest in lymphoid tissue. [PDF]

Microbiol Spectr
Eloiflin R-J, Grau-Roma L, Lasserre V, Python S, Talker S, Totte P, García-Nicolás O, Summerfield A, Bataille A.   +8 more
europepmc   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

Primary thyroid mucosa-associated lymphoid tissue marginal zone lymphoma in a 46-year-old female: a case report. [PDF]

Gland Surg
Yang J, Jiao L, Du G, Jiang S.
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Comprehensive analysis of imaging and pathological features in 20 cases of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma: a retrospective study. [PDF]

J Thorac Dis
Zhao R, Dong Y, Kong J.
europepmc   +1 more source

Generation and functional analysis of melanoma antigen‐specific CD8+ T cells derived from S/MAR vector‐transfected human induced pluripotent stem cells

International Journal of Cancer, EarlyView.
What's New? Adoptive cell therapy (ACT) with tumor antigen‐specific CD8+ T cells has shown success in clinical trials treating patients with advanced or metastatic melanoma. Here, the authors established protocols for generating CD8+ T cells from human induced pluripotent stem cells (hiPSCs) expressing a melanoma‐specific T cell receptor (TCR) or ...
Juliane Poelchen, Sandra Pardo, Daniel Novak, Qian Sun, Tamara Steinfass, Marlene Vierthaler, Özge Cicek Sener, Karol Granados Blanco, Yiman Wang, Jan Peter Nicolay, Pierre Guermonprez, Richard Harbottle, Viktor Umansky, Jochen Utikal   +13 more
wiley   +1 more source

¹⁸F-FDG PET/CT findings in a mucosa-associated lymphoid tissue lymphoma patient coexisting with primary myelofibrosis. [PDF]

Am J Nucl Med Mol Imaging
Han Y, Wu R, Zhang Y, Zhang X, Gao Z.
europepmc   +1 more source

Tumor desialylation surpasses anti‐PD‐L1 checkpoint therapy in restoring anti‐tumor immunity in a murine model for colorectal cancer

International Journal of Cancer, EarlyView.
What's New? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila, Tao Zhang, Victor Lorrain, Eelco Keuning, Laraib Amir Ali, Cora Chadick, Sara García‐García, Louis Boon, Noortje de Haan, Juan J. García‐Vallejo, Yvette van Kooyk, Sandra J. van Vliet   +11 more
wiley   +1 more source

Primary hepatic mucosa-associated lymphoid tissue lymphoma: a case report and literature review. [PDF]

Front Oncol
He T, Zou J.
europepmc   +1 more source

Clinicopathological Characteristics of Extranodal Marginal Zone Lymphoma of the Mucosa Associated Lymphoid Tissue (MALT-Lymphoma) of the Intestine: A Single Center Analysis. [PDF]

Hematol Oncol
Steinbrecher O, Kiesewetter B, Dolak W, Brand R, Simonitsch-Klupp I, Raderer M.   +5 more
europepmc   +1 more source