Results 31 to 40 of about 16,905 (208)

Rare case of primary extranodal marginal zone lymphoma of the thorax

Respiratory Medicine Case Reports, 2019
Primary lymphoma presenting a solitary lesion of the chest wall is extremely rare, as the majority of chest-wall tumors arise from metastasis. We report a case of a 64-year-old man with no history of HIV infection or pyothorax who presented with dry ...
Ahmed Ben Saad, Nesrine Fahem, Rim Khemakhem, Nouha Ben Abdeljelil, Asma Migaou, Manel Njima, Saousen Cheikh Mhamed, Samah Joobeur, Naceur Rouatbi   +8 more
doaj   +1 more source

Model‐Based Analysis with Mechanistic Insights to CAR‐T‐Cell Therapy Kinetics: Case Study with Axicabtagene Ciloleucel and Brexucabtagene Autoleucel

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed drug development is increasingly used to support chimeric antigen receptor (CAR)‐T‐cell therapy programs. However, most population pharmacokinetic (PK) CAR‐T‐cell models available in literature are variations of an empirical piecewise‐linear model, which accurately describes the observed data but lacks a mechanistic foundation.
Anna M. Mc Laughlin, Martin Bergstrand, Ana Ruiz‐Garcia, Simone Filosto, Rhine Shen   +4 more
wiley   +1 more source

Primary Orbital Lymphoma – A Challenging Diagnosis

Acta Medica Bulgarica, 2020
Background and purpose: The occurrence of primary orbital lymphoma comprises approximately 1% of non-Hodgkin’s lymphoma and 8% of extranodal lymphoma. The vast majority of orbital lymphomas are of B-cell origin, of which extranodal marginal zone B-cell ...
Vylkanov St., Trifonova K., Slaveykov K., Dzhelebov D.   +3 more
doaj   +1 more source

Extranodal Marginal Zone B-cell Lymphoma of the Ocular Adnexa [PDF]

Cancer Control, 2016
Low-grade B-cell lymphomas located around the eye present unique challenges in diagnosis and treatment. Extranodal marginal zone B-cell lymphoma is the most common lymphoma of the ocular adnexa (conjunctiva, orbit, lacrimal gland, and eyelid).A systematic search of the relevant literature was performed.
Jean, Guffey Johnson, Lauren A, Terpak, Curtis E, Margo, Reza, Setoodeh   +3 more
openaire   +2 more sources

DinoFlow: Self‐supervised pretraining in flow cytometry enables accurate detection of common hematopathological disorders

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Flow cytometry is an essential component of routine hematological lab testing. Many computational methods have been proposed for the analysis of flow cytometry data, but most have focused on supervised learning for just one or a few specific disorders.
Brendan O'Fallon, Muir Morrison, Mattia Medina Grespan, Nicholas C. Spies, David P. Ng   +4 more
wiley   +1 more source

Primary Breast Lymphoma in a 30-Year-Old Female Patient: A MALT Lymphoma or Pediatric Nodal Marginal Zone Lymphoma? A Case Report and Literature Review

Клиническая онкогематология
Primary lymphoma accounts for less than 0.5 % of all breast malignancies. One of the most ubiquitous diseases in this group is extranodal lymphoma of mucosa-associated marginal zone lymphoid tissue (MALT lymphoma).
Mariya Vladimirovna Melnikova, A. M. Kovrigina   +1 more
doaj   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

A New Diagnostic Approach Using the NLR/LMR Ratio in the Differential Diagnosis of Neck Masses: Hematologic Evaluation of Patients With Cervical Lymphadenopathy

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates complete blood count–derived inflammatory ratios for differentiating lymphoma from benign cervical lymphadenopathies. The novel NLR/LMR ratio demonstrated superior diagnostic performance (AUC = 0.71, OR = 4.6) compared with conventional indices.
Servet Erdemes, Gizem Ay Haldız, Müslüm Ayral, Ali Çetin   +3 more
wiley   +1 more source

Marginal B-cell lymphoma: A 10-year retrospective study at national institute of hematology and blood transfusion, Vietnam

SAGE Open Medicine
Objective: The prognostic factors of patients diagnosed with marginal zone B-cell lymphoma at the National Institute of Hematology and Blood Transfusion between January 2014 and January 2024 were analyzed.
Binh Duc Vu, Hung Quang Nguyen, Chiem Quang Le, Cuong Ba Nguyen, Tuong Quang Le, Anh Vu-Bao Nguyen, Thanh Hoang Nguyen, Tai Phu Le, Hieu Van Nguyen   +8 more
doaj   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source