Results 61 to 70 of about 31,001 (240)

Cutaneous Crystal‐Storing Histiocytosis With Marginal Zone Lymphoma. A Case Report With A Striking Clinical Presentation

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Cutaneous crystal‐storing histiocytosis (CSH) is an extremely rare histopathologic finding of histiocytes accumulating crystals of immunoglobulin or paraproteins, often associated with lymphoplasmacytic malignancies. It commonly presents in a wide age range of both female and male adults with a history of a lymphoproliferative disorder ...
Ashton Arlen, Brad S. Graham, Gregory A. Hosler, Marsha C. Kinney   +3 more
wiley   +1 more source

A case of primary cutaneous marginal zone B-cell lymphoma

Pifu-xingbing zhenliaoxue zazhi
We report a case of primary cutaneous marginal zone B-cell lymphoma. A 23-year-old male presented with red nodules on his back for 5 years. Physical examination revealed multiple demarcated red nodules on the back, sized 5 mm×5 mm to 10 mm×15 mm, with ...
HUANG Jiamin, SUN Zhaojun, REN Haiyue
doaj   +1 more source

Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma [PDF]

, 2009
Signaling through the Notch1 receptor has a pivotal role in early thymocyte development. Gain of Notch1 function results in the development of T-cell acute lymphoblastic leukemia in a number of mouse experimental models, and activating Notch1 mutations ...
Chiba Shigeru, Fukayama Masashi, Hangaishi Akira, Izutsu Koji, Kumano Keiki, Kurokawa Mineo, Lee Suk-young, Matsumoto Akihiko, Nakazaki Kumi, Nannya Yasuhito, Ogawa Seishi, Ota Satoshi, Ota Yasunori, Sakata-Yanagimoto Mamiko, Sanada Masashi, Seto Masao, Suzuki Ritsuro, Yagita Hideo, Yamamoto Go, 千葉 滋, 坂田（柳元） 麻実子   +20 more
core   +1 more source

A Rare Case of Cutaneous Crystal‐Storing Histiocytosis With Kappa Light Chain Restriction and Unusual BCL6 Expression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Crystal‐storing histiocytosis (CSH) is a rare histopathologic phenomenon characterized by the accumulation of crystalline material within histiocytes, most often associated with lymphoplasmacytic or plasma cell neoplasms. Cutaneous involvement is uncommon and may present diagnostic challenges.
Liangli Wang, Jonathan L. Curry, Julia Dai, Daniel H. Wang, Paolo Strati, Melody R. Becnel, Leomar Y. Ballester, Carlos A. Torres‐Cabala, Phyu P. Aung   +8 more
wiley   +1 more source

Primary Tracheal Malignant Lymphoma Detected during a Regular Checkup in an Asbestos Dust-Exposed Smoker [PDF]

, 2014
Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for ...
Kishimoto, Nobuyasu, Matsumura, Tadashi, Mizuno, Shoma, Ota, Seisuke, Shiomi, Kohei, Tanaka, Takehiro   +5 more
core   +1 more source

Diffuse CD30‐Positive Cutaneous Infiltrate in a Clinically Suspected Hidradenitis Suppurativa Lesion: Histopathologic and Diagnostic Challenges

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder affecting apocrine gland–bearing areas. We report a 38‐year‐old male with a lesion in the left axilla, initially clinically interpreted as HS and resistant to antibiotics.
R. Gervasi, G. L. Piazzetta, G. Soluri, C. Scigliano, C. Pelaia, V. Zuccalà, C. Gentile, N. Lobello, E. Allegra, E. Chiarella, N. Innaro   +10 more
wiley   +1 more source

Comparative genome profiling across subtypes of low-grade B-cell lymphoma identifies type-specific and common aberrations that target genes with a role in B-cell neoplasia

Haematologica, 2008
Background Low-grade B-cell lymphomas are a very heterogeneous group of tumors, whose differential diagnosis is frequently compromised by the lack of specific cytogenetic or molecular features.
Bibiana I. Ferreira, Juan F. García, Javier Suela, Manuela Mollejo, Francisca I. Camacho, Angel Carro, Santiago Montes, Miguel A. Piris, Juan C. Cigudosa   +8 more
doaj   +1 more source

Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies [PDF]

, 2010
Sequence variants at the TERT-CLPTM1L locus in chromosome 5p have been recently associated with disposition for various cancers. Here we show that this locus including the gene encoding the telomerase reverse-transcriptase TERT at 5p13.33 is rarely but ...
Akasaka, T. (T.), Ammerpohl, O. (Ole), Callet-Bauchu, E. (E.), Dyer, M.J.S. (Martin J. S.), Gascoyne, R.D (R. D.), Gesk, S. (Stefan), Harder, L. (Lana), Horsman, D. (D.), Klapper, W. (Wolfram), Majid, A. (Aneela), Martin-Subero, J.I. (Jose Ignacio), Martinez-Climent, J.A. (José Ángel), Nagel, I. (Inga), Siebert, R. (Reiner), Stilgenbauer, S. (Stepahn), Szczepanowski, M. (Monika), Tönnies, H. (Holger)   +16 more
core  

Circulating CAR T‐Cells After Treatment With Axicabtagene Ciloleucel in Patients With Relapsed/Refractory Aggressive B‐Cell Lymphomas and Its Association to Treatment Outcome

European Journal of Haematology, EarlyView.
ABSTRACT Objectives This study investigates the expansion of CAR T‐cells and its association to treatment outcome. Methods Patients with aggressive B‐cell lymphomas treated with anti‐CD19 CAR T‐cell therapy axicabtagene ciloleucel (axi‐cel) at Skåne and Sahlgrenska University Hospitals from 2019 to October 2024 were included.
Louise Olsson Werne, Evelina Elmér, Mikael Lisak, Róbert Pálmason, Annika K. Hult, Josefina Dykes, Mats Jerkeman   +6 more
wiley   +1 more source

Primary Pulmonary Anaplastic Large Cell Lymphoma: A Rare Malignancy and Rare Cause of the Luftsichel Sign

Case Reports in Radiology, 2018
Primary pulmonary lymphomas are rare with primary pulmonary non-Hodgkin lymphoma accounting for only 0.3% of primary lung neoplasms. Of these, the large majority are made up of marginal zone B-cell lymphoma and diffuse large B-cell lymphoma. We present a
Elizabeth Von Ende, Travis Kauffman, Philip A. Munoz, Santiago Martinez-Jiménez   +3 more
doaj   +1 more source