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2020
B cell development and activation are accompanied by dynamic genetic alterations including V(D)J rearrangements and immunoglobulin-gene somatic hypermutation and class-switch recombination. Abnormalities in these genetic events can cause chromosomal translocations and genomic mutations, leading to altered expression and function of genes involved in B ...
Xin, Meng, Qing, Min, Ji-Yang, Wang
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B cell development and activation are accompanied by dynamic genetic alterations including V(D)J rearrangements and immunoglobulin-gene somatic hypermutation and class-switch recombination. Abnormalities in these genetic events can cause chromosomal translocations and genomic mutations, leading to altered expression and function of genes involved in B ...
Xin, Meng, Qing, Min, Ji-Yang, Wang
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Current Treatment Options in Oncology, 2014
The standard frontline therapy for diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma (MCL) includes the use of chemoimmunotherapy and/or radiation therapy. When patients with these diseases relapse or are refractory to therapy, their diseases are considered incurable outside of the setting of an autologous or ...
Kami, Maddocks, Kristie A, Blum
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The standard frontline therapy for diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma (MCL) includes the use of chemoimmunotherapy and/or radiation therapy. When patients with these diseases relapse or are refractory to therapy, their diseases are considered incurable outside of the setting of an autologous or ...
Kami, Maddocks, Kristie A, Blum
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New England Journal of Medicine, 1984
The cells of most tumors are considered to be genetically homogeneous because they are assumed to represent a single clone descended from one abnormal cell. We have discovered three cases of B-cell lymphoma for which this generalization is not true.
J, Sklar +5 more
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The cells of most tumors are considered to be genetically homogeneous because they are assumed to represent a single clone descended from one abnormal cell. We have discovered three cases of B-cell lymphoma for which this generalization is not true.
J, Sklar +5 more
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Human Pathology, 1987
A case of malignant lymphoma probably representing the neoplastic counterpart of "monocytoid B cells" is described. The lymphoma cells had medium-sized, oval to indented nuclei and moderate amounts of pale cytoplasm. Immunohistochemical studies on cryostat sections revealed positive staining for pan-B, B1, B4, BA2, 12 (HLA-DR), and IgM lambda, but not ...
C S, Ng, J K, Chan
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A case of malignant lymphoma probably representing the neoplastic counterpart of "monocytoid B cells" is described. The lymphoma cells had medium-sized, oval to indented nuclei and moderate amounts of pale cytoplasm. Immunohistochemical studies on cryostat sections revealed positive staining for pan-B, B1, B4, BA2, 12 (HLA-DR), and IgM lambda, but not ...
C S, Ng, J K, Chan
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American Journal of Clinical Pathology, 1993
Monocytoid B-cell lymphoma is a distinct clinicopathologic entity occurring primarily in the lymph nodes of elderly patients. Its unique features compared with other low-grade lymphomas are also its characteristic morphologic features. These are its rare leukemic conversion and infrequent bone marrow involvement, and its relatively common association ...
S S, Shin, K, Sheibani
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Monocytoid B-cell lymphoma is a distinct clinicopathologic entity occurring primarily in the lymph nodes of elderly patients. Its unique features compared with other low-grade lymphomas are also its characteristic morphologic features. These are its rare leukemic conversion and infrequent bone marrow involvement, and its relatively common association ...
S S, Shin, K, Sheibani
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Hematology/Oncology Clinics of North America, 2019
Primary cutaneous B-cell lymphomas are non-Hodgkin lymphomas that present in the skin without evidence of extracutaneous involvement at diagnosis. There are 3 types of primary cutaneous B-cell lymphomas: primary cutaneous marginal zone lymphoma, primary cutaneous follicle center lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg-type ...
Amrita, Goyal +2 more
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Primary cutaneous B-cell lymphomas are non-Hodgkin lymphomas that present in the skin without evidence of extracutaneous involvement at diagnosis. There are 3 types of primary cutaneous B-cell lymphomas: primary cutaneous marginal zone lymphoma, primary cutaneous follicle center lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg-type ...
Amrita, Goyal +2 more
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2008
The indolent B-cell lymphomas account for about one third of all lymphomas in the Western world. The follicular lymphomas are the largest and most easily recognized category of indolent lymphoma, representing about one quarter of lymphomas in the Western world.1, 2, 3 The incidence of follicular lymphoma is markedly lower in Asia than in the West, for ...
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The indolent B-cell lymphomas account for about one third of all lymphomas in the Western world. The follicular lymphomas are the largest and most easily recognized category of indolent lymphoma, representing about one quarter of lymphomas in the Western world.1, 2, 3 The incidence of follicular lymphoma is markedly lower in Asia than in the West, for ...
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