Results 71 to 80 of about 466,743 (315)

CAR T Cell Toxicity: Current Management and Future Directions

HemaSphere, 2019
. By late 2018, 2 chimeric antigen receptor T (CAR T) cell products have been approved by US and European regulatory authorities. Tisagenlecleucel (Kymriah, Novartis) is indicated in the treatment of patients up to 25 years of age with B-cell acute ...
Lucrecia Yáñez, Miriam Sánchez-Escamilla, Miguel-Angel Perales   +2 more
doaj   +1 more source

Combined detection of lymphocyte clonality and MALT1 translocations in bronchoalveolar lavage fluid for diagnosing pulmonary lymphomas

Scientific Reports, 2021
Diagnosis of pulmonary lymphoma using small tissue samples is difficult and often requires surgical procedures; thus, a less invasive sampling method is desirable.
Takashi Kido, Hiroshi Ishimoto, Hiroshi Ishii, Kanako Hara, Mutsumi Ozasa, Hiroki Kawabata, Toshinori Kawanami, Yu Suzuki, Hiroki Yoshikawa, Atsuko Hara, Noriho Sakamoto, Nobuhiro Matsumoto, Chiharu Yoshii, Junya Fukuoka, Masaki Fujita, Masamitsu Nakazato, Junichi Kadota, Hiroshi Mukae, Kazuhiro Yatera   +18 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Whole blood EBV-DNA predicts outcome in diffuse large B-cell lymphoma

, 2016
An association between Epstein-Barr Virus (EBV) infection and lymphoproliferative diseases has been reported with EBV + diffuse large B cell-lymphoma (DLBCL) of the elderly described as a distinct entity.
Hohaus, Stefan, D'Alo', Francesco, Voso, Maria Teresa, Larocca, Luigi Maria, Bellesi, Silvia, Pompili, Maurizio, Maiolo, Elena, Tisi, Maria Chiara, Santangelo, Rosaria, Cupelli, Elisa, Giachelia, Manuela, Leone, Giuseppe, Alma, Eleonora, Martini, Maurizio   +13 more
core   +1 more source

miRNA-Based Therapies in B Cell Non-Hodgkin Lymphoma.

, 2020
Non-Hodgkin lymphoma (NHL) is a diverse class of hematological cancers, many of which arise from germinal center (GC)-experienced B cells. Thus GCs, the sites of antibody affinity maturation triggered during immune responses, also provide an environment ...
Yébenes, Fuertes, Teresa, Ramiro, Almudena R, García-Yébenes Mena, Virginia Pilar   +3 more
core   +1 more source

Intravascular large B cell lymphoma

Leukemia Research Reports, 2014
Intravascular large B cell lymphoma (IVBCL) is a rare type of extranodal large B cell lymphoma characterized by selective growth of lymphoma cells within the microvasculature.
Ricardo García-Muñoz, Susana Rubio-Mediavilla, Diego Robles-de-Castro, Aura Muñoz, Pilar Herrera-Pérez, Pilar Rabasa   +5 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Molecular Pathogenesis of MALT lymphoma

, 2011
Mucosa associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway.

core   +1 more source

Reproducibility of Gene Expression Signatures in Diffuse Large B-Cell Lymphoma [PDF]

, 2022
Multiple gene expression profiles have been identified in diffuse large B-cell lymphoma (DLBCL). Besides the cell of origin (COO) classifier, no signatures have been reproduced in independent studies or evaluated for capturing distinct aspects of DLBCL ...
van den Berg, Anke, Diepstra, Arjan; id_orcid, Pieternella J. Lugtenburg, Zijlstra, Josée, Lam, King, Marcel Nijland, Annika Seitz, Tjitske Los, Nijland, Marcel; id_orcid, van den Berg, Anke; id_orcid, Bauke Ylstra, King Lam, Wilson Araújo da Silva, Daphne de Jong, Plaça, Jessica Rodrigues, de Jong, Daphne, da Silva, Wilson Araújo, Seitz, Annika, Arjan Diepstra, Matías Mendeville, Lugtenburg, Pieternella J., Lugtenburg, Pieternella J, Anke van den Berg, Los, Tjitske, Ylstra, Bauke, Nijland, Marcel, Jessica Rodrigues Plaça, Diepstra, Arjan, Josée Zijlstra, Mendeville, Matías   +29 more
core   +1 more source

T-cell/histiocyte-rich large B-cell lymphoma presenting as a primary central nervous system lymphoma

Rare Tumors, 2015
Primary central nervous system (PCNSL) lymphoma is an aggressive extranodal non-Hodgkin lymphoma, and most cases are classified as diffuse large B-cell lymphoma (DLBCL) by histology.
Pooja Advani, Jason Starr, Abhisek Swaika, Liuyan Jiang, Yushi Qiu, Zhimin Li, Han W. Tun   +6 more
doaj   +1 more source