Results 51 to 60 of about 614,725 (210)

Composite Epstein-Barr virus-positive mucosa-associated lymphoid tissue lymphoma and Epstein-Barr virus-negative diffuse large B-cell lymphoma in the parotid salivary gland of a patient with Sjögren’s syndrome and rheumatoid arthritis: a case report

Journal of Medical Case Reports, 2020
Background Epstein-Barr virus is associated with many human hematopoietic neoplasms; however, Epstein-Barr virus-positive mucosa-associated lymphoid tissue lymphoma is extremely rare.
Vadim R. Gorodetskiy, Natalya A. Probatova, Dmitry M. Konovalov, Natalya V. Ryzhikova, Yulia V. Sidorova, Andrey B. Sudarikov, Olga V. Mukhortova   +6 more
doaj   +1 more source

Development of a novel cell line‐derived xenograft model of primary herpesvirus 8‐unrelated effusion large B‐cell lymphoma and antitumor activity of birabresib in vitro and in vivo

Cancer Medicine, 2021
Background Primary human herpesvirus 8 (HHV8)‐unrelated effusion large B‐cell lymphoma is a clinical disease entity distinct from HHV8‐positive primary effusion lymphoma (PEL).
Tomohiro Nishimori, Tomonori Higuchi, Yumiko Hashida, Takako Ujihara, Ayuko Taniguchi, Fumiya Ogasawara, Naoya Kitamura, Ichiro Murakami, Kensuke Kojima, Masanori Daibata   +9 more
doaj   +1 more source

Epstein-Barr Virus-Positive Adrenal Diffuse Large B-Cell Lymphoma after Treatment for Angioimmunoblastic T-Cell Lymphoma

European Journal of Case Reports in Internal Medicine, 2021
Angioimmunoblastic T-cell lymphoma (AITL) can be complicated by Epstein-Barr virus (EBV)-positive B-cell lymphoma. B-cell lymphoma may develop simultaneously at the time of AITL diagnosis or after treatment for AITL.
Akiko Hashimoto, Satsuki Asai, Yasuhiro Tanaka, Isaku Shinzato   +3 more
doaj   +1 more source

The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

, 2016
The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in ...
Bacon, C.M., Butterworth, J.A., Campbell, K.J., Cockell, S.J., Gewurz, B.E., Hunter, J.E., Perkins, N.D., Sellier, H., Thomas, H.D., Zhao, B.   +9 more
core   +1 more source

Is now the time for molecular driven therapy for diffuse large B-cell lymphoma? [PDF]

, 2017
INTRODUCTION: Recent genetic and molecular discoveries regarding alterations in diffuse large B-cell lymphoma (DLBCL) deeply changed the approach to this lymphoproliferative disorder.
Ansuinelli, Michela, DE ANGELIS, Federico, DI ROCCO, Alice, Foa, Roberto, Martelli, Maurizio   +4 more
core   +1 more source

Inhibition of demethylase KDM6B sensitizes diffuse large B-cell lymphoma to chemotherapeutic drugs

Haematologica, 2017
Histone methylation and demethylation regulate B-cell development, and their deregulation correlates with tumor chemoresistance in diffuse large B-cell lymphoma, limiting cure rates. Since histone methylation status correlates with disease aggressiveness
Rohit Mathur, Lalit Sehgal, Ondrej Havranek, Stefan Köhrer, Tamer Khashab, Neeraj Jain, Jan A. Burger, Sattva S. Neelapu, R. Eric Davis, Felipe Samaniego   +9 more
doaj   +1 more source

Ibrutinib in B-cell lymphoma: single fighter might be enough?

Cancer Cell International, 2020
Background In recent years, the B cell receptor (BCR) signaling pathway has become a “hot point” because it plays a critical role in B-cell proliferation and function. Bruton’s tyrosine kinase (BTK) is overexpressed in many subtypes of B-cell lymphoma as
Chao Xue, Xin Wang, Lingyan Zhang, Qingyuan Qu, Qian Zhang, Yujie Jiang   +5 more
doaj   +1 more source

Identification and validation of 5-methylcytosine-associated genes in diffuse large B-cell lymphoma

Heliyon, 2023
5-methylcytosine modifications play a significant role in carcinogenesis; however, studies exploring 5-methylcytosine-related genes in diffuse large B-cell lymphoma patients are lacking.
Cheng Xing, Shicong Zhu, Wenzhe Yan, Hongkai zhu, Zineng Huang, Yan Zhao, Wancheng Guo, Huifang Zhang, Le Yin, Xueqin Ruan, Zeyue Deng, Peilong Wang, Zhao Cheng, Zhihua Wang, Hongling Peng   +14 more
doaj   +1 more source

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth. [PDF]

, 2015
Serine-threonine kinase CK2 is highly expressed and pivotal for survival and proliferation in multiple myeloma, chronic lymphocytic leukemia and mantle cell lymphoma.
Agostinelli, C, Benvenuti, P, Casellato, A, Fuligni, F, Mandato, E, Piazza, Francesco, Pileri, Sa, Pizzi, Marco, Rugge, Massimo, Semenzato, Gianpietro Carlo   +9 more
core   +1 more source

The Combined Inhibition of SREBP and mTORC1 Signaling Synergistically Inhibits B‐Cell Lymphoma

Cancer Medicine
Background The sterol regulatory element‐binding protein (SREBP) pathway is essential for maintaining sterol homeostasis during B cell activation and germinal center B cell proliferation.
Zhenhan Zhu, Wenxia Jiang, Jiehao Zhou, Alexander Robert Maldeney, Jingru Liang, Jing Yang, Wei Luo   +6 more
doaj   +1 more source