Results 31 to 40 of about 466,743 (315)

Antibody therapy of pediatric B-cell lymphoma

Frontiers in Oncology, 2013
B-cell lymphoma in children accounts for about 10% of all pediatric malignancies. Chemotherapy has been very successful leading to an over-all 5-year survival between 80 and 90% depending on lymphoma type and extent of disease.
Friederike eMeyer-Wentrup, Verena ede Zwart, Marc eBierings   +2 more
doaj   +1 more source

Somatic hypermutation and B–cell lymphoma [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001
During the B–cell response to T–cell–dependent antigens, the B cells undergo a rapid proliferative phase in the germinal centre. This is accompanied by the introduction of mutations into the immunoglobulin (Ig) variable region (V) genes. The B cells are then selected according to the affinity of the encoded immunoglobulin for antigen, resulting in ...
Dunn-Walters, D, Thiede, C, Alpen, B, Spencer, J   +3 more
openaire   +3 more sources

Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study

Medical Journal of Dr. D.Y. Patil University, 2015
Background: Malignant lymphomas arising in extranodal sites are intriguing. The histological types of lymphomas vary from one site to another.
Chinnam Aparna, Inuganti Venkata Renuka, Muthyala Rajani, Garikapati Sailabala, Parvatala Annapurna   +4 more
doaj   +1 more source

Primary cutaneous B‐cell lymphomas [PDF]

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2011
SummaryCutaneous B‐cell lymphomas (CBCL) are the second most common form of primary cutaneous lymphomas. The cutaneous follicle center lymphoma and the cutaneous marginal zone lymphoma (extranodal MALT type lymphoma) account for the vast majority of CBCL and manifest with nodules.
Kempf, Werner, Denisjuk, Natalja, Kerl, Katrin, Cozzio, Antonio, Sander, Christian   +4 more
openaire   +4 more sources

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

, 2009
Proliferation and survival of Hodgkin and Reed/Sternberg (HRS) cells, the malignant cells of classical Hodgkin lymphoma (cHL), are dependent on constitutive activation of nuclear factor {kappa}B (NF-{kappa}B).
Inga Vater, Giefing, Maciej, Vater, Inga, Hartmann, Sylvia, Martin-Leo Hansmann, Martin-Subero, Jose Ignacio, Bohle, Verena, Küppers, Ralf, Jens Stanelle, Ralf Küppers, Sylvia Hartmann, Gunhild Mechtersheimer, Hansmann, Martin-Leo, Gesk, Stefan, Jose Ignacio Martin-Subero, Stanelle, Jens, Verena Bohle, Siebert, Reiner, Roland Schmitz, Klapper, Wolfram, Maciej Giefing, Wolfram Klapper, Mechtersheimer, Gunhild, Schmitz, Roland, Stefan Gesk, Reiner Siebert   +25 more
core   +1 more source

Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma

Scientific Reports, 2021
Chemo-immunotherapy has improved survival in B-cell lymphoma patients, but refractory/relapsed diseases still represent a major challenge, urging for development of new therapeutics.
Morten P. Oksvold, Ulrika Warpman Berglund, Helge Gad, Baoyan Bai, Trond Stokke, Idun Dale Rein, Therese Pham, Kumar Sanjiv, Geir Frode Øy, Jens Henrik Norum, Erlend B. Smeland, June H. Myklebust, Thomas Helleday, Thea Kristin Våtsveen   +13 more
doaj   +1 more source

Evolution in the Definition of Follicular Lymphoma and Diffuse Large B-Cell Lymphoma: A Model for the Future of Personalized Medicine

Hemato, 2022
The definitions of follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are evolving in the era of personalized medicine. Early stages of the evolution of FL have been recognized. Two histological manifestations of early lesions are in situ
Elaine S. Jaffe, Antonino Carbone
doaj   +1 more source

Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma : endpoints of a spectrum of one disease?

, 2013
In contrast to the commonly indolent clinical behavior of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), T cell/histiocyte rich large B cell lymphoma (THRLBCL) is frequently diagnosed in advanced clinical stages and has a poor prognosis ...
Benjamin Rengstl, Sebastian Newrzela, Randy Gascoyne, Xavier Sagaert (482298), Xavier Sagaert, Hartmann, Sylvia, Martin-Leo Hansmann, Claudia Döring, Küppers, Ralf, Chris de Wolf-Peeters, Fabio Facchetti, Ralf Küppers, Fabio Facchetti (376587), Sylvia Hartmann, Rengstl, Benjamin, Hansmann, Martin-Leo, Christian Steidl, Sagaert, Xavier, Martin-Leo Hansmann (260067), Tousseyn, Thomas, Christian Steidl (482300), Ralf Küppers (260072), Thomas Tousseyn (482297), Chris de Wolf-Peeters (482299), Steidl, Christian, Claudia Döring (474984), Ponzoni, Maurilio, Randy Gascoyne (482301), Jakobus, Christina, Wolf-Peeters, Chris de, Benjamin Rengstl (482295), Sebastian Newrzela (482296), Gascoyne, Randy, Maurilio Ponzoni (126480), Döring, Claudia, Thomas Tousseyn, Christina Jakobus (482294), Christina Jakobus, Facchetti, Fabio, Sylvia Hartmann (260069), Newrzela, Sebastian, Maurilio Ponzoni   +41 more
core   +1 more source

Suboccipital lateral injection of intrathecal chemotherapy in a patient with mantle cell lymphoma [PDF]

, 2004
Background: Even today patients who suffer from mantle cell lymphoma have a poor prognosis, especially when the CNS is involved. To confirm the diagnosis of meningeosis lymphomatosa, asservation of the liquor cerebrospinalis is necessary.
Dühmke, Eckhart, Pachmann, S., Bruning, R., Schaffer, Moshe   +3 more
core   +1 more source

Contribution of immunocytochemistry to the diagnosis of usual and unusual lymphoma cases

Journal of Cytology, 2018
Some of the limitations of fine needle aspiration (FNA) in the cytodiagnosis of lymphoma include problems encountered in differentiating reactive hyperplasia from low-grade non-Hodgkin lymphoma (NHL), lower cytodiagnostic accuracy for NHL with a ...
Dilip K Das
doaj   +1 more source