Results 21 to 30 of about 614,725 (210)

Gene expression analysis provides a potential rationale for revising the histological grading of follicular lymphomas

Haematologica, 2008
Background Follicular lymphomas are currently subdivided into grades I, II, IIIa and IIIb. This distinction is, however, questioned.Design and Methods We studied the gene expression profile of 43 follicular lymphomas, 50 B-cell non-Hodgkin’s lymphomas of
Pier Paolo Piccaluga, Andrea Califano, Ulf Klein, Claudio Agostinelli, Beatriz Bellosillo, Eva Gimeno, Sergi Serrano, Francisco Solè, Yonghui Zang, Brunangelo Falini, Pier Luigi Zinzani, Stefano A. Pileri   +11 more
doaj   +1 more source

Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type

Haematologica, 2010
Background Multiparameter flow cytometry allows the detection of minor monoclonal B-cell populations. Using this technique combined with morphology, we were struck by the presence of minor populations of small monoclonal B cells in bone marrows of ...
Anne M. Tierens, Harald Holte, Abdirashid Warsame, Ida M. Ikonomou, Junbai Wang, Wing C. Chan, Jan Delabie   +6 more
doaj   +1 more source

Inhibition of oncogenic transcription factor REL by the natural product derivative calafianin monomer 101 induces proliferation arrest and apoptosis in human B-lymphoma cell lines [PDF]

, 2015
Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB.
Chennamadhavuni, Spandan, Gilmore, Thomas D., Porco, John A., Whitty, Adrian, Yeo, Alan T.   +4 more
core   +2 more sources

Artesunate shows potent anti-tumor activity in B-cell lymphoma

Journal of Hematology & Oncology, 2018
Background Although chemo-immunotherapy has led to an improved overall survival for most B-cell lymphoma types, relapsed and refractory disease remains a challenge. The malaria drug artesunate has previously been identified as a growth suppressor in some
Thea Kristin Våtsveen, Marit Renée Myhre, Chloé Beate Steen, Sébastien Wälchli, Ole Christian Lingjærde, Baoyan Bai, Pierre Dillard, Theodossis A. Theodossiou, Toril Holien, Anders Sundan, Else Marit Inderberg, Erlend B. Smeland, June Helen Myklebust, Morten P. Oksvold   +13 more
doaj   +1 more source

Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile [PDF]

, 2009
The human REL proto-oncogene encodes a transcription factor in the nuclear factor (NF)-kappaB family. Overexpression of REL is acutely transforming in chicken lymphoid cells, but has not been shown to transform any mammalian lymphoid cell type.
Chin, M., Gilmore, T.D., Herscovitch, M., Waxman, D.J., Zhang, N.   +4 more
core   +2 more sources

B-cell multilobated lymphoma [PDF]

Cancer, 1983
A 59-year-old man was hospitalized for evaluation of cervical lymph node enlargement, and a diagnosis of a diffuse histiocytic lymphoma with B-cell markers was made. The unusual multilobated nature of the lymphoma cells is the subject of this study. The light and electron microscopic features are described and compared with those previously reported T ...
openaire   +2 more sources

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. [PDF]

, 2017
Bruton tyrosine kinase (BTK) links the B-cell antigen receptor (BCR) and Toll-like receptors with NF-κB. The role of BTK in primary central nervous system (CNS) lymphoma (PCNSL) is unknown.
Brennan, Cameron W., Campos, Carl, Clark, Owen, Codega, Paolo, DeAngelis, Lisa M., Dogan, Ahmet, Gavrilovic, Igor T., Glass, Jon, Graeber, Thomas G., Grommes, Christian, Gutin, Philip H., Hamlin, Paul, Hatzoglou, Vaios, Hsieh, Wan-Ying, Huse, Jason T., Kaley, Thomas J., Lallana, Enrico C., Mellinghoff, Ingo K., Moskowitz, Craig H., Nichol, Donna, Nolan, Craig P., Noy, Ariela, Omuro, Antonio, Palaskas, Nicolaos, Palomba, M. Lia, Panageas, Katherine S., Pastore, Alessandro, Peak, Scott, Pentsova, Elena, Reiner, Anne S., Rohle, Dan, Rosenblum, Marc, Sauter, Craig S., Schartz, Derrek, Schultz, Nikolaus, Tabar, Viviane S., Tang, Sarah S., Thomas, Alissa A., Tsyvkin, Elina, Viale, Agnes, Wolfe, Julia, Won, Minhee   +41 more
core   +2 more sources

An Unusual Presentation of B-Cell Lymphoma as a Large Isolated Epiglottic Mass: Case Report and Literature Review

Case Reports in Otolaryngology, 2016
Extranodal presentation of B-cell lymphoma is uncommon. Isolated primary epiglottic B-cell lymphoma is even rarer. To our knowledge, there has been only one description of isolated B-cell lymphoma presenting as a large epiglottic mass.
Changxing Liu, Sean Delaney, Tamara N. Brown   +2 more
doaj   +1 more source

Antibody therapy of pediatric B-cell lymphoma

Frontiers in Oncology, 2013
B-cell lymphoma in children accounts for about 10% of all pediatric malignancies. Chemotherapy has been very successful leading to an over-all 5-year survival between 80 and 90% depending on lymphoma type and extent of disease.
Friederike eMeyer-Wentrup, Verena ede Zwart, Marc eBierings   +2 more
doaj   +1 more source

Diffuse b-cell lymphoma

Journal of the Belgian Society of Radiology, 2011
Background: A 39-year-old patient took medical advice because of progressive fatigue, with nausea, fever, non specific abdominal pain, 3 weeks after coming back from Asia. He had been positive for HIV for 6 years. Blood tests show an increased CRP level (4 mg/dl, nl < 1 mg/dl).
Grosu, C, Danse, E, Dragean, A, Annet, L
openaire   +5 more sources