Results 21 to 30 of about 466,743 (315)

Epigenetics and B-cell lymphoma [PDF]

Current Opinion in Hematology, 2011
It has only recently become apparent that mutations in epigenetic mechanisms and perturbation of epigenomic patterning are frequent events in B-cell lymphomas. The purpose of this review is to highlight these new findings and provide a conceptual framework for understanding how epigenetic modifications might contribute to lymphomagenesis.Somatic ...
Rita, Shaknovich, Ari, Melnick
openaire   +2 more sources

Origin and pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma as revealed by global gene expression analysis [PDF]

, 2008
The pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma (NLPHL) and its relationship to other lymphomas are largely unknown. This is partly because of the technical challenge of analyzing its rare neoplastic lymphocytic and histiocytic (L&H ...
Tiacci, Enrico, Andreas Bräuninger, Ines Pfeil, Susan Eckerle, Ralf Küppers, Martin-Leo Hansmann, Doering, Claudia, Anja von Heydebreck, Küppers, Ralf, Brune, Verena, Bräuninger, Andreas, von Heydebreck, Anja, Enrico Tiacci, Hansmann, Martin-Leo, Verena Brune, van Noesel, Carel J. M., Klapper, Wolfram, Falini, Brunangelo, Heydebreck, Anja von, Braeuninger, Andreas, Pfeil, Ines, Brunangelo Falini, Wolfram Klapper, Claudia Döring, Metzler, Dirk, Eckerle, Susan, Döring, Claudia, Kueppers, Ralf, Carel J.M. van Noesel, Dirk Metzler   +29 more
core   +1 more source

Gene expression analysis provides a potential rationale for revising the histological grading of follicular lymphomas

Haematologica, 2008
Background Follicular lymphomas are currently subdivided into grades I, II, IIIa and IIIb. This distinction is, however, questioned.Design and Methods We studied the gene expression profile of 43 follicular lymphomas, 50 B-cell non-Hodgkin’s lymphomas of
Pier Paolo Piccaluga, Andrea Califano, Ulf Klein, Claudio Agostinelli, Beatriz Bellosillo, Eva Gimeno, Sergi Serrano, Francisco Solè, Yonghui Zang, Brunangelo Falini, Pier Luigi Zinzani, Stefano A. Pileri   +11 more
doaj   +1 more source

B-cell lymphoma of the mandible

European Annals of Otorhinolaryngology, Head and Neck Diseases, 2010
Primary malignant lymphoma of the mandible is rare. It is frequently mistaken for a dental lesion, delaying diagnosis. We here report a case of mandibular lymphoma and present the clinical and radiological characteristics and means of treatment of this pathology.A 17-year-old woman consulted for right facial tumefaction with 1 year's evolution ...
Mnejja, M., Hammami, B., Kolsi, N., Kallel, S., Chakroun, A., Charfeddine, I., Hdiji, S., Elloumi, M., Ghorbel, A.   +8 more
openaire   +2 more sources

The Role of the MYC/miR-150/MYB/ZDHHC11 Network in Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma [PDF]

, 2022
We previously described involvement of the MYC/miR-150/MYB/ZDHHC11 network in the growth of Burkitt lymphoma (BL) cells. Here we studied the relevance of this network in the two other B-cell lymphomas: Hodgkin lymphoma (HL) and diffuse large B-cell ...
van den Berg, Anke, Rutgers, Bea, Agnieszka Dzikiewicz-Krawczyk, Dzikiewicz-Krawczyk, Agnieszka, Annika Seitz, Koerts, Jasper, Joost Kluiver, Ziel-Swier, Lotteke J Y M, Rianne Veenstra, van den Berg, Anke; id_orcid, de Jong, Debora, Seitz, Annika, Debora de Jong, Jasper Koerts, Razak, Fazlyn R Abdul, Anke van den Berg, Liu, Yichen, Lotteke J. Y. M. Ziel-Swier, Bea Rutgers, Veenstra, Rianne, Fazlyn R. Abdul Razak, Kluiver, Joost, Yichen Liu, Kluiver, Joost; id_orcid, Liu, Yichen; id_orcid   +24 more
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Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type

Haematologica, 2010
Background Multiparameter flow cytometry allows the detection of minor monoclonal B-cell populations. Using this technique combined with morphology, we were struck by the presence of minor populations of small monoclonal B cells in bone marrows of ...
Anne M. Tierens, Harald Holte, Abdirashid Warsame, Ida M. Ikonomou, Junbai Wang, Wing C. Chan, Jan Delabie   +6 more
doaj   +1 more source

Artesunate shows potent anti-tumor activity in B-cell lymphoma

Journal of Hematology & Oncology, 2018
Background Although chemo-immunotherapy has led to an improved overall survival for most B-cell lymphoma types, relapsed and refractory disease remains a challenge. The malaria drug artesunate has previously been identified as a growth suppressor in some
Thea Kristin Våtsveen, Marit Renée Myhre, Chloé Beate Steen, Sébastien Wälchli, Ole Christian Lingjærde, Baoyan Bai, Pierre Dillard, Theodossis A. Theodossiou, Toril Holien, Anders Sundan, Else Marit Inderberg, Erlend B. Smeland, June Helen Myklebust, Morten P. Oksvold   +13 more
doaj   +1 more source

MicroRNA Signatures In B-Cell Lymphomas [PDF]

Blood, 2010
Abstract Abstract 4155 Beyond the conventional criteria of lymphoma classification (integrated clinical, morphological, immunophenotypic, and molecular features) additional markers are still required for a more precise differential diagnosis and a better understanding of lymphoma pathogenesis.
Di Lisio, Lorena, Sánchez-Beato, Margarita, Gómez López, Gonzalo, Rodríguez, María Eugenia, Montes-Moreno, Santiago, Mollejo, Manuela, Menárguez, Javier, Martínez Hernández, Miguel Ángel, Alvés, Francisco J., Pisano, David G., Piris, Miguel Ángel, Martínez, Nerea   +11 more
openaire   +4 more sources

Burkitt-like lymphoma with 11q aberration: a germinal center-derived lymphoma genetically unrelated to Burkitt lymphoma

Haematologica, 2019
Burkitt-like lymphoma with 11q aberration is characterized by pathological features and gene expression profile resembling those of Burkitt lymphoma but lacks the MYC rearrangement and carries an 11q-arm aberration with proximal gains and telomeric ...
Blanca Gonzalez-Farre, Joan Enric Ramis-Zaldivar, Julia Salmeron-Villalobos, Olga Balagué, Verónica Celis, Jaime Verdu-Amoros, Ferran Nadeu, Constantino Sábado, Antonio Ferrández, Marta Garrido, Federico García-Bragado, María Dolores de la Maya, José Manuel Vagace, Carlos Manuel Panizo, Itziar Astigarraga, Mara Andrés, Elaine S. Jaffe, Elias Campo, Itziar Salaverria   +18 more
doaj   +1 more source

An Unusual Presentation of B-Cell Lymphoma as a Large Isolated Epiglottic Mass: Case Report and Literature Review

Case Reports in Otolaryngology, 2016
Extranodal presentation of B-cell lymphoma is uncommon. Isolated primary epiglottic B-cell lymphoma is even rarer. To our knowledge, there has been only one description of isolated B-cell lymphoma presenting as a large epiglottic mass.
Changxing Liu, Sean Delaney, Tamara N. Brown   +2 more
doaj   +1 more source