Results 11 to 20 of about 382,253 (265)
Epigenetics and B-cell lymphoma [PDF]
It has only recently become apparent that mutations in epigenetic mechanisms and perturbation of epigenomic patterning are frequent events in B-cell lymphomas. The purpose of this review is to highlight these new findings and provide a conceptual framework for understanding how epigenetic modifications might contribute to lymphomagenesis.Somatic ...
Rita, Shaknovich, Ari, Melnick
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B-cell lymphoma of the mandible
Primary malignant lymphoma of the mandible is rare. It is frequently mistaken for a dental lesion, delaying diagnosis. We here report a case of mandibular lymphoma and present the clinical and radiological characteristics and means of treatment of this pathology.A 17-year-old woman consulted for right facial tumefaction with 1 year's evolution ...
Mnejja, M. +8 more
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Background Follicular lymphomas are currently subdivided into grades I, II, IIIa and IIIb. This distinction is, however, questioned.Design and Methods We studied the gene expression profile of 43 follicular lymphomas, 50 B-cell non-Hodgkin’s lymphomas of
Pier Paolo Piccaluga +11 more
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Abstract Large B‐cell lymphoma, the prototype of aggressive non‐Hodgkin lymphomas, is both the most common lymphoma and accounts for the highest global burden of lymphoma‐related deaths. For nearly 4 decades, the goal of treatment has been “cure”, first based on CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone), and ...
Barraclough, Allison +3 more
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Background Multiparameter flow cytometry allows the detection of minor monoclonal B-cell populations. Using this technique combined with morphology, we were struck by the presence of minor populations of small monoclonal B cells in bone marrows of ...
Anne M. Tierens +6 more
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Antibody therapy of pediatric B-cell lymphoma
B-cell lymphoma in children accounts for about 10% of all pediatric malignancies. Chemotherapy has been very successful leading to an over-all 5-year survival between 80 and 90% depending on lymphoma type and extent of disease.
Friederike eMeyer-Wentrup +2 more
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Artesunate shows potent anti-tumor activity in B-cell lymphoma
Background Although chemo-immunotherapy has led to an improved overall survival for most B-cell lymphoma types, relapsed and refractory disease remains a challenge. The malaria drug artesunate has previously been identified as a growth suppressor in some
Thea Kristin Våtsveen +13 more
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MicroRNA Signatures In B-Cell Lymphomas [PDF]
Abstract Abstract 4155 Beyond the conventional criteria of lymphoma classification (integrated clinical, morphological, immunophenotypic, and molecular features) additional markers are still required for a more precise differential diagnosis and a better understanding of lymphoma pathogenesis.
Di Lisio, Lorena +11 more
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Extranodal presentation of B-cell lymphoma is uncommon. Isolated primary epiglottic B-cell lymphoma is even rarer. To our knowledge, there has been only one description of isolated B-cell lymphoma presenting as a large epiglottic mass.
Changxing Liu +2 more
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Background: Malignant lymphomas arising in extranodal sites are intriguing. The histological types of lymphomas vary from one site to another.
Chinnam Aparna +4 more
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