Results 101 to 110 of about 45,441 (213)

Next‐generation sequencing‐based IG clonality analysis to discriminate reactive infiltrates from minimal lymphoma involvement in paired lymphoma and bone marrow biopsies; a EuroClonality‐NGS Working Group study

Histopathology, Volume 88, Issue 5, Page 1059-1074, April 2026.
Next‐generation sequencing (NGS) immunoglobulin clonality analysis can help resolve ambiguous bone marrow staging biopsies for B‐cell lymphoma. In this study, paired analysis of the primary lymphoma and bone marrow helped to detect lymphoma involvement in cases with inconclusive morphology and immunohistochemistry, making it a valuable tool for ...
Michiel van den Brand, Meilinde Leenders, Jos Rijntjes, Jeroen A.C.W. Luijks, Anton W. Langerak, Konnie M. Hebeda, Patricia J.T.A. Groenen   +6 more
wiley   +1 more source

The impact of cyclin D1 mRNA isoforms, morphology and p53 in mantle cell lymphoma: p53 alterations and blastoid morphology are strong predictors of a high proliferation index

Haematologica, 2012
Background Mantle cell lymphoma is a clinically heterogeneous disease characterized by overexpression of cyclin D1 protein. Blastoid morphology, high proliferation, and secondary genetic aberrations are markers of aggressive behavior.
Julia Slotta-Huspenina, Ina Koch, Laurence de Leval, Gisela Keller, Margit Klier, Karin Bink, Marcus Kremer, Mark Raffeld, Falko Fend, Leticia Quintanilla-Martinez   +9 more
doaj   +1 more source

Impact of novel therapies for mantle cell lymphoma in the real world setting : a report from the UK's Haematological Malignancy Research Network (HMRN) [PDF]

, 2018
The treatment landscape for mantle cell lymphoma (MCL) has changed dramatically in recent years, with findings from clinical trials reporting improvements in survival. Data on the general patient population are, however, sparse; and it is unclear whether
Abrahamsson, Abrahamsson, Andersen, Atilla, Chandran, Colbourn, Dreyling, Dreyling, Dreyling, Epperla, Furtado, Gouill, Harris, Herrmann, Hill, Hoster, Hoster, Kahl, Klapper, Kluin-Nelemans, Kuittinen, Kurnaz, Leonard, Leux, Marcos-Gragera, Martin, Martin, Martin, McKay, Rule, Rule, Rummel, Rummel, Sawalha, Schulz, Smith, Smith, Swerdlow, Vergote, Vidal, Wang, Zaja   +41 more
core   +1 more source

Cutaneous lesions as presentation form of mantle cell lymphoma

Dermatology Reports, 2011
Mantle cell lymphoma is a type of no-Hodgkin lymphoma that affects extranodal areas, especially, bone narrow, digestive tract and Waldeyer ring. Here we report a case of mantle cell lymphoma IV Ann Arbor stage with cutaneous lesions on nasal dorsum and ...
Nayra Merino de Paz, Marina Rodriguez-Martin, Patricia Contreras Ferrer, Sonia Garcia-Hernandez, Nieves Hernandez de Leon, Antonio Martin-Herrera, Antonio Noda-Cabrera   +6 more
doaj   +1 more source

Nanomedicine for the Treatment of Non-Hodgkin Lymphoma [PDF]

, 2019
Non-Hodgkin lymphoma, or NHL, is the predominant category of lymphoma. NHL is a type of lymphoid hematopoietic malignancy which approximately 70,000 Americans are diagnosed with annually, with the number of diagnoses growing annually.
Gandhi, B.Pharm, Tanvi
core   +1 more source

Targeted therapy in lymphoma [PDF]

, 2010
Discovery of new treatments for lymphoma that prolong survival and are less toxic than currently available agents represents an urgent unmet need. We now have a better understanding of the molecular pathogenesis of lymphoma, such as aberrant signal ...
Patrick B Johnston, RuiRong Yuan, Franco Cavalli, Thomas E Witzig   +3 more
core   +1 more source

Significance of Bcl-2 and Bcl-6 immunostaining in B-Non Hodgkin's lymphoma

Hematology Reports, 2011
The determination of prognosis for B-Non- Hodgkin’s lymphoma (NHL) is known to be related to the multiple differences in tumor cell biology. Bcl-2 and Bcl-6 are two markers linked to germinal center B cells.
Hanan Mohamed Mahmoud, Yasmin Nabil Elsakhawy   +1 more
doaj   +1 more source

Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas [PDF]

, 2007
Integrative genomic and gene-expression analyses have identified amplified oncogenes in B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize tumor suppressor genes within homozygous deletions remains unexplored.
Agirre-Ena, X. (Xabier), Beltran, E. (E.), Climent, J. (J.), Dyer, M.J.S. (Martin J. S.), Fresquet, V. (Vicente), Garcia, J.F. (José Francisco), Karran, E.L. (E. L.), Marin, M. (Miguel), Martinez-Climent, J.A. (José Ángel), Marugan, I. (Isabel), Mestre-Escorihuela, C. (Cinta), Pinkel, D. (Daniel), Prosper, F. (Felipe), Richter, J.A. (José Ángel), Rosenwald, A. (Andreas), Rubio-Moscardo, F. (Fanny), Sanchez, L. (Lydia), Siebert, R. (Reiner), Staudt, L.M. (Louis M.), Sugimoto, K.J. (Kei-Ji), Wheat, L.M. (Luise M.)   +20 more
core  

Telomere protein complexes and their role in lymphoid malignancies [PDF]

, 2017
Telomeres are highly regulated and dynamic complexes that protect the genomic DNA and prevent the end of linear chromosomes from being misrecognized as a broken DNA.
Dos Santos, Patricia Carolina, Panero, Julieta, Slavutsky, Irma Rosa   +2 more
core  

Adhesion molecule profiles of B-cell non-Hodgkin's lymphomas in the leukemic phase

Brazilian Journal of Medical and Biological Research, 2006
We evaluated the expression of 10 adhesion molecules on peripheral blood tumor cells of 17 patients with chronic lymphocytic leukemia, 17 with mantle-cell lymphoma, and 13 with nodal or splenic marginal B-cell lymphoma, all in the leukemic phase and ...
D.M. Matos, E.G. Rizzatti, A.B. Garcia, D.A.P. Gallo, R.P. Falcão   +4 more
doaj