Archives of Pathology & Laboratory Medicine, 1999 Abstract Objective.—This article summarizes the most useful ancillary immunohistochemical and molecular assays for use in the diagnosis of mantle cell lymphoma. Data Sources.—The English language literature was surveyed, with an emphasis on recent publications, for articles presenting key advances in the molecular ...
Rebecca C. Hankin, Susan Hunter
openaire +3 more sources
Interferon gamma inducible protein 16 (IFI16) expression is reduced in mantle cell lymphoma
Heliyon, 2019 IFI16, member of the IFN-inducible PYHIN-200 gene family, modulates proliferation, survival and differentiation of different cell lineages. In particular, IFI16 expression, which is regulated during the differentiation of B cells, was recently studied in
Pier Paolo Piccaluga +13 more
doaj +1 more source
IGHV mutational status of nodal marginal zone lymphoma by NGS reveals distinct pathogenic pathways with different prognostic implications [PDF]
, 2019 The precise B cell of origin and molecular pathogenesis of nodal marginal zone lymphoma (NMZL) remain poorly defined. To date, due to the rarity of NMZL, the vast majority of already-published studies have been conducted on a limited number of samples ...
Amato, Teresa +15 more
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A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
Journal of Investigative Medicine High Impact Case Reports, 2021 Lactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma.
Kok Hoe Chan MD +5 more
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A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response [PDF]
, 2019 The ImbruVeRCHOP trial is an investigator-initiated, multicenter, single-arm, open label Phase I/II study for patients 61-80 years of age with newly diagnosed CD20+ diffuse large B-cell lymphoma and a higher risk profile (International Prognostic Index ...
Anagnostopoulos, Ioannis +7 more
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World Journal of Surgical Oncology, 2009 Background Mantle cell lymphoma (MCL) is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. Extra nodal involvement is present in the majority of cases,
Abo Stephen M +6 more
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Non-Nodal CD5-Negative Mantle Cell Lymphoma with Secondary TP53 Deletion
Case Reports in Hematology, 2020 Mantle cell lymphoma is a non-Hodgkin lymphoproliferative neoplasm with several clinical and morphologic variants linked, primarily, through genetic derangement of the cyclin D1 locus.
Robert K. McCall +2 more
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RNA inhibition highlights cyclin D1 as a potential therapeutic target for mantle cell lymphoma. [PDF]
PLoS ONE, 2012 Mantle cell lymphoma is characterized by a genetic translocation results in aberrant overexpression of the CCND1 gene, which encodes cyclin D1. This protein functions as a regulator of the cell cycle progression, hence is considered to play an important ...
Shiri Weinstein +8 more
doaj +1 more source
Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]
, 2018 Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO +8 more
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Mantle Cell Lymphoma Presenting with Acute Bilateral Ophthalmoplegia
Türk Oftalmoloji Dergisi, 2017 A 72-year-old woman presented with acute onset of double vision, bilateral complete blepharoptosis, and nearly complete ophthalmoplegia. Orbital and brain magnetic resonance imaging were normal.
Yaran Koban +6 more
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