Results 41 to 50 of about 138,230 (307)

Anti-programmed cell death protein-1/ligand-1 therapy in different cancers. [PDF]

open access: yes, 2015
Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby promoting immune responses against several cancer types ...
Homet Moreno, B, Ribas, A
core   +2 more sources

Extranodal non-Hodgkin's lymphoma [PDF]

open access: yesCancer, 1980
From 1964 to 1977, 42 patients with Stages I and II non-Hodgkin's lymphoma involving the extranodal sites were seen and treated with curative intent by radiotherapy in the Department of Therapeutic Radiology at Rush-Presbyterian-St. Luke's Medical Center.
S, Reddy   +3 more
openaire   +2 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

A Rare Case of Lambert-Eaton Myasthenia Syndrome Associated with Non-Hodgkin’s Lymphoma: A Case Report and Review of the Literature

open access: yesCase Reports in Oncology, 2023
Introduction: Lambert-Eaton myasthenia syndrome (LEMS) is a rare autoimmune disorder characterized by autoantibodies targeting presynaptic neuromuscular junctions. It results in muscle weakness and autonomic dysfunction.
Mohammad Abu-Tineh   +6 more
doaj   +1 more source

An unusual case of late recurrent Hodgkin lymphoma presenting with soft tissue masses [PDF]

open access: yes, 2015
Hodgkin lymphoma remains primarily a nodal disease. Extranodal involvement in Hodgkin lymphoma is less common than that seen in non-Hodgkin lymphoma. In particular, extranodal Hodgkin lymphoma involving soft tissues is extremely rare. We report a case of
Deng, Aileen   +3 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Non-Hodgkin lymphoma in the developing world: review of 4539 cases from the International Non-Hodgkin Lymphoma Classification Project

open access: yesHaematologica, 2016
The distribution of non-Hodgkin lymphoma subtypes varies around the world, but a large systematic comparative study has never been done. In this study, we evaluated the clinical features and relative frequencies of non-Hodgkin lymphoma subtypes in five ...
Anamarija M. Perry   +8 more
doaj   +1 more source

Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis [PDF]

open access: yes, 2016
The nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the ...
Banu, Petrisor   +3 more
core   +3 more sources

Non-Hodgkin lymphoma and pre-existing conditions: spectrum, clinical characteristics and outcome in 213 children and adolescents

open access: yesHaematologica, 2016
Children and adolescents with pre-existing conditions such as DNA repair defects or other primary immunodeficiencies have an increased risk of non-Hodgkin lymphoma. However, large-scale data on patients with non-Hodgkin lymphoma and their entire spectrum
Andishe Attarbaschi   +25 more
doaj   +1 more source

Non-Hodgkin and Hodgkin Lymphomas Select for Overexpression of BCLW. [PDF]

open access: yes, 2017
Purpose: B-cell lymphomas must acquire resistance to apoptosis during their development. We recently discovered BCLW, an antiapoptotic BCL2 family member thought only to contribute to spermatogenesis, was overexpressed in diffuse large B-cell lymphoma ...
Adams, Clare M.   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy