Results 61 to 70 of about 10,191,051 (291)

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

HIV ASSOCIATED LYMPHOMA – TWO CASE REPORT SERIES [PDF]

Romanian Journal of Infectious Diseases, 2016
Combined antiretroviral therapy significantly improved the prognosis and the life expectancy of HIV patients. Along with this, the profile of HIV associated malignant pathologies has changed. Among these, lymphoma, with a higher incidence than in general
Liana-Cătălina Gavriliu, Otilia-Elisabeta Benea   +1 more
doaj   +1 more source

NON-HODGKIN'S LYMPHOMA

Pediatric Clinics of North America, 1997
Pediatric lymphomas are the third most common group of malignancies in children and adolescents. Unlike lymphomas in adults, pediatric lymphomas are diffuse, aggressive neoplasms with a propensity for widespread dissemination. Intensification of conventional treatment approaches along with improvements in supportive care have resulted in dramatic ...
A, Shad, I, Magrath
openaire   +2 more sources

Malignant lymphomas (ML) and HIV/AIDS Infection in Tanzania. [PDF]

, 2008
\ud HIV infection is reported to be associated with some malignant lymphomas (ML) so called AIDS-related lymphomas (ARL), with an aggressive behavior and poor prognosis.
Mwakigonja Amos R, Mgaya, Edward M, Mwakigonja, Amos R, Kaaya Ephata E, Mgaya Edward M, Kaaya, Ephata E   +5 more
core   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Cerebral type MALT non Hodgkin lymphoma

Revista Cubana de Medicina Militar, 2021
Introduction: Non-Hodgkin's lymphomas generally have their origin in the lymphoid system, there is a great diversity of them, which makes their classification and definitive pathological diagnosis difficult.
Yaimara Zunen Hernández Puentes, Yordan Rodríguez Hernández, Mercedes Rita Salinas Olivares, Wendolin Rodríguez Borges   +3 more
doaj  

CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma

Haematologica, 2018
Chemotherapy and hematopoietic stem cell transplantation are effective treatments for most Hodgkin lymphoma patients, however there remains a need for better tumor-specific target therapy in Hodgkin lymphoma patients with refractory or relapsed disease ...
Ziduo Li, Xinsheng Ju, Kenneth Lee, Candice Clarke, Jennifer L. Hsu, Edward Abadir, Christian E. Bryant, Suzanne Pears, Neroli Sunderland, Scott Heffernan, Annemarie Hennessy, Tsun-Ho Lo, Geoffrey A. Pietersz, Fiona Kupresanin, Phillip D. Fromm, Pablo A. Silveira, Con Tsonis, Wendy A. Cooper, Ilona Cunningham, Christina Brown, Georgina J. Clark, Derek N.J. Hart   +21 more
doaj   +1 more source

Non-Hodgkin lymphoma

BMJ, 2018
The term non-Hodgkin lymphoma (NHL) covers a spectrum of malignant disorders arising from cells of the immune system and manifesting predominantly as lymphadenopathy or solid tumour. The classification of NHL is complex and ever-evolving, with more than 50 different subtypes listed in the latest WHO classification of lymphoma (1).
Bowzyk Al-Naeeb, Anna, Ajithkumar, Thankamma, Behan, Sarah, Hodson, Daniel James   +3 more
openaire   +3 more sources

Management of non-Hodgkin's lymphomas [PDF]

Postgraduate Medical Journal, 1999
Summary The non-Hodgkin's lymphomas (NHL) are a heterogenous group of disorders characterised by malignant proliferation of lymphoid cells. The cellular origin is relatively well established with subtypes corresponding to the various stages of lymphocyte differentiation. The term encompasses a hotchpotch of conditions with very different
Mounter PJ, Lennard AL
openaire   +2 more sources

Outcomes after alemtuzumab-containing reduced-intensity allogeneic transplantation regimen for relapsed and refractory non-Hodgkin lymphoma [PDF]

, 2004
We report the outcomes after reduced-intensity conditioning allogeneic stem cell transplantation (RIT) for non-Hodgkin lymphoma (NHL) in 88 patients (low-grade NHL [LG-NHL], n = 41; high-grade NHL [HG-NHL], n = 37; mantle cell lymphoma [MCL], n = 10 ...
Mahendra, P, Smith, GM, Cook, G., Hatton, C., Tighe, J., Morris, E., Goldstone, A, Peggs, K., Cook, G, Mahendra, Premini, Hunter, A., Mackinnon, S, Milligan, D., Smith, G.M., Goldstone, A., Chopra, R, Hunter, A, Linch, D., Parker, A, Linch, D, Morris, E, Hunter, A.H., Milligan, D, Thomson, K, Parker, A., Peggs, K, Chopra, R., Thomson, K., Craddock, C., Hatton, C, Mackinnon, S., Milligan, Donald, Mahendra, P., Schey, S., Craddock, Charles; id_orcid, Craddock, C, Schey, S, Tighe, J   +37 more
core   +1 more source