Results 51 to 60 of about 34,204 (229)

Rare case of primary extranodal marginal zone lymphoma of the thorax

Respiratory Medicine Case Reports, 2019
Primary lymphoma presenting a solitary lesion of the chest wall is extremely rare, as the majority of chest-wall tumors arise from metastasis. We report a case of a 64-year-old man with no history of HIV infection or pyothorax who presented with dry ...
Ahmed Ben Saad, Nesrine Fahem, Rim Khemakhem, Nouha Ben Abdeljelil, Asma Migaou, Manel Njima, Saousen Cheikh Mhamed, Samah Joobeur, Naceur Rouatbi   +8 more
doaj   +1 more source

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo, Cinetto, Francesco, Crescenzi, Ludovica, Milito, Cinzia, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Rizzo, Francesca, Santangeli, Enrico, Spadaro, Giuseppe, Tabolli, Stefano, Valente, Michele   +11 more
core   +3 more sources

Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. [PDF]

, 2017
The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses ...
Abba, Al Kadah, Albasri, Carlton A. Evans, Cesar Ugarte-Gil, Chau, Daniela E. Kirwan, David A. J. Moore, de Noronha, Eduardo D. Matos, Eduardo Ticona, Eza, Gustavo Cerrillo, Hansen, Jaime Cok, Jon S. Friedland, José Luis Cabrera, Kirwan, Landis, Lawn, Moore, Moore, Muller, Ojo, Olu-Eddo, Olu-Eddo, Ondounda, Osores, Pangalis, Park, Richner, Robert H. Gilman, Silva, Sobonya, Sridhar, Sterling, Syed M. Hasan Rizvi   +36 more
core   +2 more sources

Primary effusion lymphoma: current perspectives

OncoTargets and Therapy, 2018
Primary effusion lymphoma (PEL) is a rare and aggressive disease, affecting a unique population of patients who are often elderly or immunocompromised. PEL is associated with human herpesvirus type-8 infection and most commonly presents as malignant effusions of the body cavities.
Mayur Narkhede, Shagun Arora, Chaitra Ujjani   +2 more
openaire   +4 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Primary HHV-8 (-) Effusion-Based Non-Germinal Center B Cell Diffuse Large B Cell Lymphoma Successfully Treated with Standard Anthracycline-Based Chemoimmunotherapy

Journal of Blood Medicine, 2021
Justin Kuhlman,1 Muhamad Alhaj Moustafa,2 Liuyan Jiang,3 Han W Tun2 1Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL, USA; 3Department of Pathology and ...
Kuhlman J, Alhaj Moustafa M, Jiang L, Tun HW   +3 more
doaj  

Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature

Turkish Journal of Hematology, 2013
Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin lymphoma that presents with serosal effusion in body cavities, without obvious tumor masses.
Sonay Güven Karataş, Reyhan Bayrak, Özlem Şahin Balçık, Kadir Serkan Yalçın, Esra Atıcı, Ümit Akyıldız, Ali Koşar   +6 more
doaj   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Multiple human herpesvirus-8 infection [PDF]

, 2003
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM, Cook, RD, Hodgson, TA, Kondowe, W, Molyneux, EM, Porter, SR, Scully, CM, Teo, CG   +7 more
core   +1 more source

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

Advanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang, Dongpeng Jiang, Peng Ke, Xiaosen Bian, Lili Zhang, Ying Zhang, Tingting Zhu, Weiwei Qu, Wenhui Qi, Yang Xu, Chengcheng Fu, Depei Wu, Jianhong Chu   +12 more
wiley   +1 more source