Results 1 to 10 of about 5,348 (208)

Primary Effusion Lymphoma: A Timely Review on the Association With HIV, HHV8, and EBV

Diagnostics, 2022
Primary effusion lymphoma (PEL) is defined by the WHO classification as a large B-cell neoplasm without detectable tumor masses. It is universally associated with HHV8, with most cases occurring in the setting of immunodeficiency such as HIV infection ...
Chih-Yi Liu, Chih-Yi Liu, Shih-Sung Chuang   +2 more
exaly   +4 more sources

Concurrent Monkeypox, HHV8, and Other Opportunistic Infections in a Human Immunodeficiency Virus Patient with Disseminated Kaposi Sarcoma: A Case Report [PDF]

Case Reports in Oncology
Introduction: Human immunodeficiency virus (HIV) infection predisposes patients to opportunistic infections. Kaposi sarcoma (KS) is a soft tissue sarcoma caused by human herpesvirus-8 (HHV8). Patients with high HHV8 and HIV viremia can develop
Maggie H. Zhou, Jeffrey A. Thomas, Shari R. Lipner, Igor Matushansky   +3 more
doaj   +2 more sources

Case Report: HHV8-positive multicentric Castleman disease in an HIV-positive patient :diagnostic challenges arising from atypical histology and the role of metagenomic sequencing [PDF]

Frontiers in Oncology
BackgroundMulticentric Castleman disease (MCD), especially the HHV8-positive subtype, is a rare lymphoproliferative disorder that presents considerable diagnostic and therapeutic difficulties, particularly among HIV-positive patients.
Wei Zhang, Rui Huang, Jing Yuan
doaj   +2 more sources

Comparative study of clinical features, pathology, and immunophenotype between HIV-related cutaneous and visceral Kaposi’s sarcoma [PDF]

BMC Cancer
Background Kaposi’s sarcoma (KS) remains a significant challenge in HIV-infected individuals, with visceral KS posing a greater therapeutic dilemma due to its aggressive nature compared to the cutaneous form.
Jingjing Xu, Jing Zhou, Xiaoli Huang, Minmin Wu, Wenjuan Guo, Keyu Liu, Yuexiang Yang, Guangling Yang, Shu Song   +8 more
doaj   +2 more sources

Expression of CD40L on CD4+ T cells distinguishes active versus inactive HIV-associated Kaposi's Sarcoma

Cancer Treatment and Research Communications, 2021
Kaposi's sarcoma (KS) is a malignancy of vascular origin. It is caused by the Kaposi's sarcoma-associated herpes virus (KSHV). Immune dysregulation is a key feature in the development and progression of KS. The main aim of this study was to determine and
Owen Ngalamika, Musonda Kawimbe, Marie Claire Mukasine   +2 more
doaj   +1 more source

Human Herpes Virus 8 in HIV-1 infected individuals receiving cancer chemotherapy and stem cell transplantation. [PDF]

PLoS ONE, 2018
BACKGROUND:Human Herpes Virus 8 (HHV8) can cause Kaposi's Sarcoma (KS) in immunosuppressed individuals. However, little is known about the association between chemotherapy or hematopoietic stem cell transplantation (HSCT), circulating HHV8 DNA levels ...
Louise E Hogan, Emily Hanhauser, Kristen S Hobbs, Christine D Palmer, Yvonne Robles, Stephanie Jost, Anne S LaCasce, Jeremy Abramson, Ayad Hamdan, Francisco M Marty, Daniel R Kuritzkes, Timothy J Henrich   +11 more
doaj   +1 more source

Sensitivity and specificity of D2-40 in differentiating Kaposi sarcoma from its mimickers

Journal of the Egyptian Women’s Dermatologic Society, 2021
Background Kaposi sarcoma (KS) is a low-grade malignant vascular neoplasm, whose etiology is associated with human herpes virus 8 (HHV8). Owing to its broad clinicopathological spectrum, KS mimics a variety of non-KS vascular lesions both clinically and ...
Rasha M Genedy, Ashraf M Hamza, Amany A Abdel Latef, Ali Alwi El-Beity   +3 more
doaj   +1 more source

Development of a novel cell line‐derived xenograft model of primary herpesvirus 8‐unrelated effusion large B‐cell lymphoma and antitumor activity of birabresib in vitro and in vivo

Cancer Medicine, 2021
Background Primary human herpesvirus 8 (HHV8)‐unrelated effusion large B‐cell lymphoma is a clinical disease entity distinct from HHV8‐positive primary effusion lymphoma (PEL).
Tomohiro Nishimori, Tomonori Higuchi, Yumiko Hashida, Takako Ujihara, Ayuko Taniguchi, Fumiya Ogasawara, Naoya Kitamura, Ichiro Murakami, Kensuke Kojima, Masanori Daibata   +9 more
doaj   +1 more source

HHV8-unrelated primary effusion lymphoma: Two case reports and a review of literature

Current Problems in Cancer: Case Reports, 2021
Although non-Hodgkin lymphoma (NHL), a cancer of the lymph nodes, may at times present as malignant pleural, pericardial, or peritoneal primary effusions, Primary Effusion Lymphoma (PEL) is a rare and aggressive subtype which lacks any distinguishable ...
Ryan W. Kendall, Ricky A. Thompson, Christopher P. Garwacki, Alan Z. Skarbnik   +3 more
doaj   +1 more source

Concurrent HIV viral blips during two episodes of multicentric Castleman disease in an adult on antiretroviral therapy: Implication for HIV persistence

IDCases, 2021
Human herpesvirus-8 (HHV8)-associated multicentric Castleman disease (HHV8-MCD) is a rare nonmalignant lymphoproliferative disorder most commonly observed in PLWH.
Ilyse Darwish, Cecilia Costiniuk, Nadine Kronfli, David Haegert, Jean-Pierre Routy   +4 more
doaj   +1 more source