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Concurrent Monkeypox, HHV8, and Other Opportunistic Infections in a Human Immunodeficiency Virus Patient with Disseminated Kaposi Sarcoma: A Case Report [PDF]

open access: yesCase Reports in Oncology
Introduction: Human immunodeficiency virus (HIV) infection predisposes patients to opportunistic infections. Kaposi sarcoma (KS) is a soft tissue sarcoma caused by human herpesvirus-8 (HHV8). Patients with high HHV8 and HIV viremia can develop
Maggie H. Zhou   +3 more
doaj   +3 more sources

Primary Effusion Lymphoma: A Timely Review on the Association with HIV, HHV8, and EBV

open access: yesDiagnostics, 2022
Primary effusion lymphoma (PEL) is defined by the WHO classification as a large B-cell neoplasm without detectable tumor masses. It is universally associated with HHV8, with most cases occurring in the setting of immunodeficiency such as HIV infection ...
Chih-Yi Liu   +2 more
exaly   +4 more sources

Case Report: HHV8-positive multicentric Castleman disease in an HIV-positive patient :diagnostic challenges arising from atypical histology and the role of metagenomic sequencing [PDF]

open access: yesFrontiers in Oncology
BackgroundMulticentric Castleman disease (MCD), especially the HHV8-positive subtype, is a rare lymphoproliferative disorder that presents considerable diagnostic and therapeutic difficulties, particularly among HIV-positive patients.
Wei Zhang, Rui Huang, Jing Yuan
doaj   +2 more sources

VALUTAZIONE VIREMIA HHV8 IN MALATTIE LINFOPROLIFERATIVE HHV8 RELATE

open access: yesMicrobiologia Medica, 2007
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A. Marus   +8 more
doaj   +3 more sources

Comparative study of clinical features, pathology, and immunophenotype between HIV-related cutaneous and visceral Kaposi’s sarcoma [PDF]

open access: yesBMC Cancer
Background Kaposi’s sarcoma (KS) remains a significant challenge in HIV-infected individuals, with visceral KS posing a greater therapeutic dilemma due to its aggressive nature compared to the cutaneous form.
Jingjing Xu   +8 more
doaj   +2 more sources

The utilization of microbial cell-free DNA next-generation sequencing for the detection of human herpesvirus-8 in a quaternary care center [PDF]

open access: yesTherapeutic Advances in Infectious Disease
Background: Human herpesvirus-8 (HHV8) can present with cutaneous or extracutaneous manifestations. While violaceous skin lesions characterize cutaneous Kaposi sarcoma, extracutaneous HHV8 is challenging to diagnose due to nonspecific symptoms ...
Rebecca Berger   +4 more
doaj   +2 more sources

KSHV/HHV8-Associated Lymphoproliferative Disorders: Lessons Learnt from People Living with HIV

open access: yesHemato, 2021
In 1992, Kaposi sarcoma herpesvirus (KSHV/HHV8) was discovered and identified as the causative agent for Kaposi sarcoma. Subsequently, the presence of this virus has been detected in a number of lymphoproliferative disorders in people living with HIV ...
Mark Bower, Antonino Carbone
exaly   +3 more sources

Expression of CD40L on CD4+ T cells distinguishes active versus inactive HIV-associated Kaposi's Sarcoma

open access: yesCancer Treatment and Research Communications, 2021
Kaposi's sarcoma (KS) is a malignancy of vascular origin. It is caused by the Kaposi's sarcoma-associated herpes virus (KSHV). Immune dysregulation is a key feature in the development and progression of KS. The main aim of this study was to determine and
Owen Ngalamika   +2 more
doaj   +1 more source

Human Herpes Virus 8 in HIV-1 infected individuals receiving cancer chemotherapy and stem cell transplantation. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:Human Herpes Virus 8 (HHV8) can cause Kaposi's Sarcoma (KS) in immunosuppressed individuals. However, little is known about the association between chemotherapy or hematopoietic stem cell transplantation (HSCT), circulating HHV8 DNA levels ...
Louise E Hogan   +11 more
doaj   +1 more source

Sensitivity and specificity of D2-40 in differentiating Kaposi sarcoma from its mimickers

open access: yesJournal of the Egyptian Women’s Dermatologic Society, 2021
Background Kaposi sarcoma (KS) is a low-grade malignant vascular neoplasm, whose etiology is associated with human herpes virus 8 (HHV8). Owing to its broad clinicopathological spectrum, KS mimics a variety of non-KS vascular lesions both clinically and ...
Rasha M Genedy   +3 more
doaj   +1 more source

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