Results 51 to 60 of about 34,386 (239)

‘Discovering’ primary effusion lymphoma in Malawi [PDF]

AIDS, 2018
Primary effusion lymphoma (PEL) is a rare non-Hodgkin lymphoma (NHL) associated with human herpesvirus 8 (HHV8) and increased incidence among HIV-positive individuals. PEL rarely presents as solid tumor masses, or extracavitary PEL (EPEL). We found one case of PEL and no EPEL reported from sub-Saharan Africa (SSA), despite high prevalence of HIV and ...
Montgomery, Nathan D, Gopal, Satish, Dhungel, Bal Mukunda, Zuze, Takondwa, Krysiak, Robert, Kaimila, Bongani, Randall, Cara, Kampani, Coxcilly, Tomoka, Tamiwe, Kasonkanji, Edwards, Seguin, Ryan, Painschab, Matthew S, Chimzimu, Fred, Fedoriw, Yuri, Mulenga, Maurice   +14 more
openaire   +1 more source

Rare case of primary extranodal marginal zone lymphoma of the thorax

Respiratory Medicine Case Reports, 2019
Primary lymphoma presenting a solitary lesion of the chest wall is extremely rare, as the majority of chest-wall tumors arise from metastasis. We report a case of a 64-year-old man with no history of HIV infection or pyothorax who presented with dry ...
Ahmed Ben Saad, Nesrine Fahem, Rim Khemakhem, Nouha Ben Abdeljelil, Asma Migaou, Manel Njima, Saousen Cheikh Mhamed, Samah Joobeur, Naceur Rouatbi   +8 more
doaj   +1 more source

Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas. [PDF]

, 2017
IntroductionCurrently, the detection of pathogens or mutations associated with intraocular lymphomas heavily relies on prespecified, directed PCRs. With metagenomic deep sequencing (MDS), an unbiased high-throughput sequencing approach, all pathogens as ...
Acharya, Nisha, Bloomer, Michele, DeRisi, Joseph L, Doan, Thuy, Gonzales, John, Shantha, Jessica G, Wilson, Michael R   +6 more
core   +1 more source

Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. [PDF]

, 2017
The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses ...
Abba, Al Kadah, Albasri, Carlton A. Evans, Cesar Ugarte-Gil, Chau, Daniela E. Kirwan, David A. J. Moore, de Noronha, Eduardo D. Matos, Eduardo Ticona, Eza, Gustavo Cerrillo, Hansen, Jaime Cok, Jon S. Friedland, José Luis Cabrera, Kirwan, Landis, Lawn, Moore, Moore, Muller, Ojo, Olu-Eddo, Olu-Eddo, Ondounda, Osores, Pangalis, Park, Richner, Robert H. Gilman, Silva, Sobonya, Sridhar, Sterling, Syed M. Hasan Rizvi   +36 more
core   +2 more sources

Primary effusion lymphoma: current perspectives

OncoTargets and Therapy, 2018
Primary effusion lymphoma (PEL) is a rare and aggressive disease, affecting a unique population of patients who are often elderly or immunocompromised. PEL is associated with human herpesvirus type-8 infection and most commonly presents as malignant effusions of the body cavities.
Mayur Narkhede, Shagun Arora, Chaitra Ujjani   +2 more
openaire   +4 more sources

Primary HHV-8 (-) Effusion-Based Non-Germinal Center B Cell Diffuse Large B Cell Lymphoma Successfully Treated with Standard Anthracycline-Based Chemoimmunotherapy

Journal of Blood Medicine, 2021
Justin Kuhlman,1 Muhamad Alhaj Moustafa,2 Liuyan Jiang,3 Han W Tun2 1Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL, USA; 3Department of Pathology and ...
Kuhlman J, Alhaj Moustafa M, Jiang L, Tun HW   +3 more
doaj  

Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature

Turkish Journal of Hematology, 2013
Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin lymphoma that presents with serosal effusion in body cavities, without obvious tumor masses.
Sonay Güven Karataş, Reyhan Bayrak, Özlem Şahin Balçık, Kadir Serkan Yalçın, Esra Atıcı, Ümit Akyıldız, Ali Koşar   +6 more
doaj   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Extracavitary Manifestation of Primary Effusion Lymphoma as a Right Atrial Mass [PDF]

, 2013
Primary effusion lymphoma (PEL) is a subset of large B cell lymphomas and has been mostly associated with human immunodeficiency virus infection. Rare cases have been reported in organ transplant recipients and chronic hepatitis C patients.
Guddati, Achuta K, Marak, Creticus P., Ponea, Ana M., Shaheen, Shagufta, Shim, Chang   +4 more
core   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source