Results 11 to 20 of about 147,528 (279)

Genetic and epigenetic insights into cutaneous T-cell lymphoma.

open access: yesBlood, 2021
Primary cutaneous T-cell lymphomas (CTCL) constitute a heterogeneous group of non-Hodgkin T-cell lymphomas that present in the skin. In recent years significant progress has been made in the understanding of the pathogenesis of CTCL.
C. Tensen, K. Quint, M. Vermeer
semanticscholar   +1 more source

Cutaneous T cell lymphomas [PDF]

open access: yesBMJ, 1994
Mycosis fungoides and the Sezary syndrome, together known as the cutaneous T cell lymphomas,1,2 are low grade non-Hodgkin's lymphomas with a mature helper T cell phenotype and monoclonal rearrangements of the T cell receptor genes. They should not be confused with intermediate and high grade non -Hodgkin's lymphomas of T cell origin affecting the skin -
N Smith, M Spittle
openaire   +6 more sources

Interleukin-17 Genes Polymorphisms are Significantly Associated with Cutaneous T-cell Lymphoma Susceptibility

open access: yesActa Dermato-Venereologica, 2022
Tumour microenvironment has an important effect on the progression of cutaneous T-cell lymphomas. Using PCR with sequence-specific primers, this study analysed single-nucleotide polymorphisms in the interleukin-17 genes of 150 patients with cutaneous T ...
Karol Kołkowski   +5 more
doaj   +1 more source

Cutaneous T‐cell lymphoma [PDF]

open access: yesJournal of the European Academy of Dermatology and Venereology, 2003
ABSTRACTCutaneous T‐cell lymphoma (CTCL) is a neoplasm of helper T cells whose first manifestations usually appear in the skin. The various forms of CTCL are distinguished by both clinical features and histopathology. Early on, the diagnosis may be difficult to establish because of its numerous, and often non‐specific, clinical presentations.
EA Kotz, D Anderson, BH Thiers
openaire   +4 more sources

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

open access: yesNature Communications, 2020
Cutaneous T cell lymphomas (CTCL) are rare but aggressive cancers without effective treatments. While a subset of patients derive benefit from PD-1 blockade, there is a critically unmet need for predictive biomarkers of response. Herein, we perform CODEX
D. Phillips   +17 more
semanticscholar   +1 more source

CD30-positive cutaneous lymphoma: report of four cases with an emphasis on clinicopathological correlations [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: The classification of cutaneous lymphomas is multidisciplinary and requires the correlation between clinical, histopathological, immunohistochemical, and molecular diagnostic elements. In this article, we present four different cases of CD30-positive T-
Thiago Jeunon de Sousa Vargas   +2 more
doaj   +2 more sources

Primary cutaneous T-cell lymphoma: experience from the Peruvian National Cancer Institute [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Background: Primary cutaneous T-cell lymphomas constitute a heterogeneous and rare group of diseases with regional particularities in Latin America.
Rosana Ruiz   +5 more
doaj   +1 more source

Dysregulated Expression of Antimicrobial Peptides in Skin Lesions of Patients with Cutaneous T-cell Lymphoma

open access: yesActa Dermato-Venereologica, 2020
Mycosis fungoides and Sézary syndrome belong to the group of primary cutaneous T-cell lymphomas. Because of the inflammatory appearance of the skin lesions, we hypothesized that antimicrobial peptides might be dysregulated in these conditions, similar to
Ulrike Wehkamp   +3 more
doaj   +1 more source

Cutaneous Involvement of Extranodal NK/T Cell Lymphoma, Nasal Type, a Clinical and Histopathological Mimicker of Various Skin Diseases

open access: yesDermatopathology, 2022
Background: Extranodal NK/T cell lymphoma, nasal type (ENK/T) with cutaneous involvement has various histopathological findings and diverse clinical manifestations.
Preeyawat Ngamdamrongkiat   +4 more
doaj   +1 more source

Cutaneous T-cell lymphoma [PDF]

open access: yesCancer, 1976
A comparison of the detailed features and natural history of 12 patients with "Sézary Syndrome" with those in patients with classical "mycosis fungoides" has demonstrated that, with the exception of a leukemic phase in the former, the two syndromes are indistinguishable.
Philip S. Schein   +2 more
openaire   +3 more sources

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