Results 11 to 20 of about 198,756 (335)
Scientific Reports, 2021 T-cell non-Hodgkin’s lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin’s lymphoma to identify mutational ...
Christine L. Jones +7 more
doaj +2 more sources
New Therapies and Immunological Findings in Cutaneous T-Cell Lymphoma
Frontiers in Oncology, 2018 Primary cutaneous lymphomas comprise a group of lymphatic malignancies that occur primarily in the skin. They represent the second most common form of extranodal non-Hodgkin’s lymphoma and are characterized by heterogeneous clinical, histological ...
Kazuyasu Fujii
doaj +2 more sources
Nature Communications, 2022 Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of non-Hodgkin lymphoma distinguished by the presence of clonal malignant T cells. The heterogeneity of malignant T cells and the complex tumor microenvironment remain poorly characterized.
Xiangjun Liu +27 more
semanticscholar +1 more source
Blood Advances, 2021 Key Points Final ALCANZA data confirm more durable responses and longer PFS with brentuximab vedotin vs control in CD30+ cutaneous T-cell lymphoma. Brentuximab vedotin extended the time to next treatment vs physician's choice, suggesting that durable ...
S. Horwitz +25 more
semanticscholar +1 more source
Genetic and epigenetic insights into cutaneous T-cell lymphoma.
Blood, 2021 Primary cutaneous T-cell lymphomas (CTCL) constitute a heterogeneous group of non-Hodgkin T-cell lymphomas that present in the skin. In recent years significant progress has been made in the understanding of the pathogenesis of CTCL.
C. Tensen, K. Quint, M. Vermeer
semanticscholar +1 more source
Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma
Nature Communications, 2020 Cutaneous T cell lymphomas (CTCL) are rare but aggressive cancers without effective treatments. While a subset of patients derive benefit from PD-1 blockade, there is a critically unmet need for predictive biomarkers of response. Herein, we perform CODEX
D. Phillips +17 more
semanticscholar +1 more source
Primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphomas: reappraisal of a provisional entity in the 2016 WHO classification of cutaneous lymphomas. [PDF]
, 2017 Primary cutaneous CD8-positive aggressive epidermotropic T-cell lymphoma is a rare and poorly characterized variant of cutaneous lymphoma still considered a provisional entity in the latest 2016 World Health Organization Classification of Cutaneous ...
Duvic, Madeleine +19 more
core +1 more source
Cellular Interactions and Inflammation in the Pathogenesis of Cutaneous T-Cell Lymphoma
Frontiers in Cell and Developmental Biology, 2020 Cutaneous T-cell lymphoma (CTCL) comprises a group of lymphoproliferative diseases characterized by the accumulation of malignant T cells in chronically inflamed skin lesions.
Veronica Stolearenco +7 more
semanticscholar +1 more source
Cutaneous T-cell lymphoma [PDF]
Cancer, 1976 A comparison of the detailed features and natural history of 12 patients with "Sézary Syndrome" with those in patients with classical "mycosis fungoides" has demonstrated that, with the exception of a leukemic phase in the former, the two syndromes are indistinguishable.
P S, Schein, J S, Macdonald, R, Edelson
openaire +2 more sources
Loss of the candidate tumor suppressor ZEB1 (TCF8, ZFHX1A) in Sézary syndrome [PDF]
, 2018 Cutaneous T-cell lymphoma is a group of incurable extranodal non-Hodgkin lymphomas that develop from the skin-homing CD4+ T cell. Mycosis fungoides and Sézary syndrome are the most common histological subtypes.
Benucci, Roberto +9 more
core +2 more sources