Results 21 to 30 of about 14,561,710 (295)

Interleukin-17 Genes Polymorphisms are Significantly Associated with Cutaneous T-cell Lymphoma Susceptibility

open access: yesActa Dermato-Venereologica, 2022
Tumour microenvironment has an important effect on the progression of cutaneous T-cell lymphomas. Using PCR with sequence-specific primers, this study analysed single-nucleotide polymorphisms in the interleukin-17 genes of 150 patients with cutaneous T ...
Karol Kołkowski   +5 more
doaj   +1 more source

Increased Chlormethine-Induced DNA Double-Stranded Breaks in Malignant T Cells from Mycosis Fungoides Skin Lesions

open access: yesJID Innovations, 2022
Mycosis fungoides (MF) is a type of cutaneous T-cell lymphoma. Chlormethine (CL) is recommended as first-line therapy for MF, with a major purpose to kill tumor cells through DNA alkylation.
Yun-Tsan Chang   +5 more
doaj   +1 more source

The function and origin of the CD4+ T cell in the classical Hodgkin lymphoma microenvironment [PDF]

open access: yes, 2012
PhDClassical Hodgkin lymphoma (CHL) is a germinal centre B cell malignancy where the bulk of the tumour comprises a non-clonal immune infiltrate enriched for CD4+ T cells.
Greaves, Paul
core   +4 more sources

Dysregulated Expression of Antimicrobial Peptides in Skin Lesions of Patients with Cutaneous T-cell Lymphoma

open access: yesActa Dermato-Venereologica, 2020
Mycosis fungoides and Sézary syndrome belong to the group of primary cutaneous T-cell lymphomas. Because of the inflammatory appearance of the skin lesions, we hypothesized that antimicrobial peptides might be dysregulated in these conditions, similar to
Ulrike Wehkamp   +3 more
doaj   +1 more source

CD30-positive cutaneous lymphoma: report of four cases with an emphasis on clinicopathological correlations [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: The classification of cutaneous lymphomas is multidisciplinary and requires the correlation between clinical, histopathological, immunohistochemical, and molecular diagnostic elements. In this article, we present four different cases of CD30-positive T-
Thiago Jeunon de Sousa Vargas   +2 more
doaj   +2 more sources

Primary Cutaneous Anaplastic Large Cell Lymphoma—A Review of Clinical, Morphological, Immunohistochemical, and Molecular Features

open access: yesCancers, 2023
Simple Summary Primary cutaneous anaplastic large cell lymphoma (ALCL) is the second most common cutaneous T-cell lymphoma after mycosis fungoides. Although it usually presents as a localized nodule or papule (>2 cm), multifocal lesions may occur in some
C. Ortiz-Hidalgo, S. Pina-Oviedo
semanticscholar   +1 more source

Primary cutaneous T-cell lymphoma: experience from the Peruvian National Cancer Institute [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Background: Primary cutaneous T-cell lymphomas constitute a heterogeneous and rare group of diseases with regional particularities in Latin America.
Rosana Ruiz   +5 more
doaj   +1 more source

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

open access: yesNature Communications, 2020
Cutaneous T cell lymphomas (CTCL) are rare but aggressive cancers without effective treatments. While a subset of patients derive benefit from PD-1 blockade, there is a critically unmet need for predictive biomarkers of response. Herein, we perform CODEX
Garry P. Nolan   +17 more
semanticscholar   +1 more source

Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. [PDF]

open access: yes, 2011
Peripheral T-cell lymphomas (PTCL) are generally less common and pursue a more aggressive clinical course than B-cell lymphomas, with the T-cell phenotype itself being a poor prognostic factor in adult non-Hodgkin lymphoma (NHL).
Graham P. Collins   +34 more
core   +2 more sources

Cellular Interactions and Inflammation in the Pathogenesis of Cutaneous T-Cell Lymphoma

open access: yesFrontiers in Cell and Developmental Biology, 2020
Cutaneous T-cell lymphoma (CTCL) comprises a group of lymphoproliferative diseases characterized by the accumulation of malignant T cells in chronically inflamed skin lesions.
Veronica Stolearenco   +7 more
semanticscholar   +1 more source

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