Results 21 to 30 of about 47,232 (218)

Potentials of brentuximab vedotin in the treatment of relapse/refractory cutaneous T-cell lymphomas: literature review and authors’ observation

Vestnik Dermatologii i Venerologii, 2019
Primary cutaneous T-cell lymphomas encompass a heterogeneous group of T-cell lymphoproliferative disorders developing primarily in the skin and characterized by a number of specific diagnostic, clinical, and therapeutic features.
L. G. Gorenkova, S. K. Kravchenko, I. E. Belousova   +2 more
doaj   +1 more source

Epidemiological, anatomopathological, and immunophenotypical aspects of cutaneous lymphomas in dogs

Pesquisa Veterinária Brasileira, 2023
: Cutaneous lymphomas are uncommon tumors in dogs that can occur as epitheliotropic and non-epitheliotropic types. The epitheliotropic type comprises three, already well established, distinct clinicopathological presentations.
Renata D. Mazaro, Douglas M. Lorenzetti, Suzana M.G. Leite, Eduardo K. Masuda, Leonardo D. Da Costa, Rosemeri O. Vasconcelos, Antonio Flávio M. Dantas, Luciana C. Lacerda, Tereza Cristina Da Silva, Marco Aurélio A. Motta, Bruno Cogliati, Rafael A. Fighera   +11 more
doaj   +1 more source

Mycosis Fungoides: Tumour d′emblee

Indian Dermatology Online Journal, 2012
Mycosis Fungoides is a Cutaneous T-cell lymphoma characterized by infiltration of skin with patches, plaques, and nodules composed of T-lymphocytes.
Rita Vora, Syed Mubashir, Parag Talavia, Gopikrishnan Anjaneyan   +3 more
doaj   +1 more source

Non-mycosis fungoides cutaneous lymphomas in a referral center in Taiwan: A retrospective case series and literature review.

PLoS ONE, 2020
BACKGROUND:While mycosis fungoides (MF) and Sézary syndrome (SS) are the most common cutaneous lymphomas (CLs), there is limited data about non-MF/SS CLs. OBJECTIVE:We aimed to evaluate clinical characteristics of non-MF/SS CLs.
Kwei-Lan Liu, Wen-Chien Tsai, Chih-Hung Lee   +2 more
doaj   +1 more source

Cutaneous Lymphoma in a Tertiary Skin Hospital and Referral Centre in Nepal

Journal of Nepal Health Research Council
Background: Primary cutaneous lymphomas are a distinct group of rare lymphoid neoplasms with absence of extracutaneous lymphomas at the time of presentation.
Ram Chandra Adhikari, Mahesh Shah, Werner Kempf, Anil Kumar Jha   +3 more
doaj   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Update on primary cutaneous T-cell lymphomas rare subtypes

Dermatology Reports
Rare subtypes of cutaneous T-cell lymphomas (CTCL) include four entities, primary cutaneous γδ T-cell lymphoma, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, and primary cutaneous CD4+ small/medium T-cell ...
Silvia Alberti-Violetti, Emilio Berti
doaj   +1 more source

Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case

Лечащий Врач, 2021
The diagnosis of primary cutaneous CD4+ pleomorphic T-cell lymphoma of the skin from small and medium-sized cells is difficult due to the rare occurrence of this nosology.
N. V. Zilberberg, M. M. Kokhan, G. D. Safonova, O. G. Rimar, I. A. Kuklin, V. A. Iglikov   +5 more
doaj   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Cutaneous T-Cell Lymphoma and Microbiota: Etiopathogenesis and Potential New Therapeutic Targets

Dermatology Research and Practice
Objective. To review the scientific literature related to human microbiota and cutaneous T-cell lymphoma. Methodology. An exploratory and systematic review of the articles retrieved from the bibliographic databases MEDLINE (PubMed), Embase, The Cochrane ...
Daniel Rodríguez Baeza, Lía Bejarano Antonio, Marta González de Arriba, José Antonio Picó-Monllor, Javier Cañueto, Vicente Navarro-Lopez   +5 more
doaj   +1 more source