Results 241 to 250 of about 187,246 (326)

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi   +5 more
wiley   +1 more source

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun   +10 more
wiley   +1 more source

From Morphology to Gene Expression Profiling in Mycosis Fungoides: Is It Still a Diagnostic Challenge? [PDF]

open access: yesDiagnostics (Basel)
Filosa A   +6 more
europepmc   +1 more source

Depletion of M2-like tumor-associated macrophages delays cutaneous T-cell lymphoma development in vivo.

open access: yesJournal of Investigative Dermatology, 2014
Xuesong Wu   +7 more
semanticscholar   +1 more source

Collisional variant of CD8+ mycosis fungoides and indolent CD8+ lymphoid proliferation

open access: yesJAAD Case Reports, 2020
Adriana Lopez, MD   +3 more
doaj  

Pharmacovigilance study for the identification of mogamulizumab-induced immune-related adverse events using a real-world database. [PDF]

open access: yesOncologist
Miyata K   +13 more
europepmc   +1 more source

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