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Peripheral T-cell lymphoma, not otherwise specified

open access: yesJournal of Family Medicine and Primary Care, 2017
The peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) belongs to a heterogeneous class of aggressive neoplasms. Although several morphologic subtypes of this tumor have been described, no particular genetic, immunological, or distinct ...
Kunal Kishor Jha   +3 more
doaj   +3 more sources

Therapeutic challenges in peripheral T-cell lymphoma

open access: yesMolecular Cancer
Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of hematological malignancies. Compared to our knowledge of B-cell tumors, our understanding of T-cell leukemia and lymphoma remains less advanced, and a significant number of patients ...
Yunpeng Luan   +10 more
doaj   +2 more sources

Indolent peripheral T-cell lymphoma resembling Kimura's disease: a new variant of T-cell Lymphoma? [PDF]

open access: yesLeukemia Research Reports
Kimura's disease (KD) is a rare chronic inflammatory disorder of unknown etiology prevalent in middle-aged Asian males. Kimura's disease transforming to T-cell lymphoma or coexisting with T-cell lymphoma have not been reported in the scientific ...
Hui Sun   +5 more
doaj   +2 more sources

Histone modifier gene mutations in peripheral T-cell lymphoma not otherwise specified

open access: yesHaematologica, 2018
Due to heterogeneous morphological and immunophenotypic features, approximately 50% of peripheral T-cell lymphomas are unclassifiable and categorized as peripheral T-cell lymphomas, not otherwise specified.
Meng-Meng Ji   +13 more
doaj   +2 more sources

Therapeutic options in peripheral T cell lymphoma

open access: yesJournal of Hematology & Oncology, 2016
Peripheral T cell lymphoma (PTCL) is a rare and heterogeneous group of non-Hodgkin lymphomas with a very poor prognosis. The standard first-line treatments have resulted in unsatisfactory patient outcomes.
Yaping Zhang   +3 more
doaj   +2 more sources

Pathogenesis of Peripheral T Cell Lymphoma.

open access: yesAnnual Review of Pathology: Mechanisms of Disease, 2018
Peripheral T cell lymphomas (PTCLs) are highly heterogeneous tumors, displaying distinct clinical and biological features. The pathogenesis and normal counterpart of such entities have been elusive for decades. Recent studies have, however, disclosed key mechanisms of peripheral T cell transformation, including (a) the deregulation of signaling ...
M. Pizzi   +2 more
semanticscholar   +4 more sources

Peripheral T cell lymphoma: Not otherwise specified

open access: yesIndian Journal of Dermatology, 2015
Peripheral T cell lymphoma (PTCL) is a heterogeneous group of hematological tumors originating from mature T cells, which constitutes less than 15% of all non-Hodgkins lymphomas in adults.
Anusha H Pai   +3 more
doaj   +3 more sources

Comparison of Allogeneic Stem Cell Transplant and Autologous Stem Cell Transplant in Refractory or Relapsed Peripheral T-Cell Lymphoma

open access: yesJAMA Network Open, 2021
Key Points Question Is allogeneic hematopoietic stem cell transplant (HSCT) or autologous HSCT more effective and safer for patients with refractory or relapsed peripheral T-cell lymphoma? Findings In this systematic review and meta-analysis of 30 trials
Jun Du   +4 more
semanticscholar   +1 more source

Genetic Landscape of Peripheral T-Cell Lymphoma

open access: yesLife, 2022
Peripheral T-Cell lymphoma (PTCL) comprises a heterogenous group of uncommon lymphomas derived from mature, post-thymic or “peripheral” T- and natural killer cells. The World Health Organization (WHO) emphasizes a multiparameter approach in the diagnosis
Vivian Hathuc, Friederike Kreisel
doaj   +1 more source

Peripheral T-cell lymphoma [PDF]

open access: yesCancer, 1989
Peripheral T-cell lymphoma is the most common type of T-cell lymphoma seen in adults in the United States. Clinical data were reviewed from 134 cases of peripheral T-cell lymphoma diagnosed in three centers. The median age of the patients was 57 years (range, 4-97 years), 59% were male, and 36 patients (27%) had a history of a preceding disorder of the
James O. Armitage   +10 more
openaire   +2 more sources

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